Monoclonal Gammopathy of Undetermined Significance MGUS Panel Test
Understanding Monoclonal Gammopathy of Undetermined Significance
Monoclonal Gammopathy of Undetermined Significance (MGUS) represents a premalignant condition characterized by the presence of abnormal plasma cells in the bone marrow that produce monoclonal proteins without causing symptoms or organ damage. This condition affects approximately 3% of the population over age 50 and carries a lifelong risk of progressing to multiple myeloma or related plasma cell disorders. The MGUS Panel Test provides comprehensive evaluation to detect and monitor this potentially serious condition.
What the MGUS Panel Test Measures
Our advanced MGUS Panel utilizes multiple sophisticated laboratory techniques to provide a complete assessment:
- Protein Electrophoresis, Serum: Separates serum proteins to identify abnormal monoclonal protein spikes
- Immunotyping, Serum: Characterizes the specific type of immunoglobulin involved (IgG, IgA, IgM)
- Kappa/Lambda Light Chains Free, Serum: Measures free light chain ratios to detect imbalances indicating monoclonal proliferation
Who Should Consider MGUS Testing
This test is recommended for individuals experiencing:
- Unexplained protein abnormalities in routine blood tests
- Persistent bone pain or unexplained fractures
- Anemia, fatigue, or weakness without clear cause
- Recurrent infections or immune system concerns
- Family history of multiple myeloma or plasma cell disorders
- Abnormal kidney function or proteinuria
- Age over 50 with routine health screening
Clinical Benefits of MGUS Detection
Early identification of monoclonal gammopathy provides significant advantages:
- Proactive Monitoring: Enables regular follow-up to detect progression early
- Risk Stratification: Helps determine individual risk for developing multiple myeloma
- Preventive Care: Allows for lifestyle modifications and preventive measures
- Peace of Mind: Provides clarity for patients with unexplained symptoms
- Timely Intervention: Facilitates early treatment if progression occurs
Understanding Your Test Results
Your MGUS Panel results will include detailed information about:
- Monoclonal Protein Presence: Detection and quantification of abnormal proteins
- Immunoglobulin Type: Identification of specific antibody classes involved
- Light Chain Ratio: Assessment of kappa/lambda balance
- Risk Assessment: Evaluation of progression risk based on protein levels and ratios
Normal results indicate no detectable monoclonal proteins, while abnormal findings may suggest MGUS requiring regular monitoring. Your healthcare provider will discuss the clinical significance of your specific results and recommend appropriate follow-up care.
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $238 |
| Regular Price | $376 |
Convenient Testing Across the USA
We have diagnostic centers conveniently located throughout the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art facilities ensure accurate testing with rapid turnaround times.
Book Your MGUS Panel Test Today
Take control of your health with comprehensive MGUS screening. Our specialized panel provides crucial information for early detection and monitoring of monoclonal gammopathy. With next-day results and expert interpretation, you’ll receive the information you need to make informed healthcare decisions.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your MGUS Panel Test or to speak with our healthcare specialists about your testing needs.
Test Specifications
- Turnaround Time: Sample Daily by 9 am; Report Next day
- Sample Type: 3 mL (2 mL min.) serum from 1 SST. Ship refrigerated or frozen. Grossly hemolysed samples not acceptable.
- Test Components: Protein Electrophoresis, Serum; Immunotyping, Serum; Kappa/Lambda Light chains Free, Serum
- Pre-test Instructions: No special preparation required
- Specialty: Hematologist, Nephrologist, Oncologist
- Department: ELECTROPHORESIS
- Method: Capillary Electrophoresis, Agarose Gel Electrophoresis, Immunofixation, Nephelometry
- Disease Type: Multiple Myeloma

