Microarray 60K POC Couple Karyotyping: Comprehensive Genetic Analysis for Pregnancy Loss
Understanding Microarray 60K POC Couple Karyotyping
Microarray 60K POC Couple Karyotyping represents a cutting-edge approach to genetic testing that combines the precision of microarray technology with the comprehensive analysis of traditional karyotyping. This advanced diagnostic test is specifically designed to investigate the genetic causes behind pregnancy loss, fetal abnormalities, and recurrent miscarriages. By examining chromosomal structures at an unprecedented resolution, this test provides couples with definitive answers about their reproductive health journey.
What This Test Measures and Detects
The Microarray 60K POC Couple Karyotyping test employs sophisticated genetic analysis techniques to identify:
- Chromosomal abnormalities including aneuploidies (extra or missing chromosomes)
- Submicroscopic deletions and duplications that traditional karyotyping might miss
- Structural chromosomal rearrangements
- Copy number variations (CNVs) associated with developmental disorders
- Genetic imbalances that could explain pregnancy complications
Who Should Consider This Test?
This comprehensive genetic analysis is particularly recommended for:
- Couples experiencing recurrent pregnancy loss (two or more miscarriages)
- Individuals with a history of fetal abnormalities detected during pregnancy
- Couples with unexplained infertility issues
- Those with a family history of genetic disorders or chromosomal abnormalities
- Women of advanced maternal age (35 years and older) planning pregnancy
- Couples seeking answers after a pregnancy termination due to fetal anomalies
Clinical Indications and Symptoms
The test is especially valuable when:
- Previous pregnancies resulted in miscarriage without clear cause
- Ultrasound examinations revealed fetal structural abnormalities
- There’s a history of stillbirth or neonatal death
- Couples are preparing for assisted reproductive technologies
- There’s concern about inherited genetic conditions
Benefits of Microarray 60K POC Couple Karyotyping
Choosing this advanced genetic testing approach offers numerous advantages:
- Higher Resolution Detection: Identifies chromosomal abnormalities at a much finer resolution than standard karyotyping
- Comprehensive Analysis: Provides simultaneous assessment of products of conception and parental samples
- Improved Diagnostic Yield: Detects up to 15-20% more abnormalities compared to traditional methods
- Future Planning Guidance: Offers valuable information for subsequent pregnancy planning and management
- Emotional Closure: Provides answers that can help couples understand and process their pregnancy loss
- Personalized Care: Enables healthcare providers to offer targeted counseling and management strategies
Test Methodology and Technology
Our Microarray 60K POC Couple Karyotyping utilizes state-of-the-art Agilent microarray technology combined with traditional cell culture methods. This dual approach ensures:
- High-density genomic coverage with 60,000 probes
- Detection of imbalances as small as 50-100 kilobases
- Comprehensive assessment of all chromosomal regions
- Integration of microarray findings with conventional cytogenetic analysis
Understanding Your Test Results
Interpreting your Microarray 60K POC Couple Karyotyping results requires professional genetic counseling. Here’s a general guide to understanding potential outcomes:
Normal Results
A normal result indicates that no significant chromosomal abnormalities were detected in the analyzed samples. This can provide reassurance for future pregnancies, though it doesn’t completely eliminate all possible genetic causes.
Abnormal Results
If chromosomal abnormalities are identified, our genetic counselors will provide detailed explanations about:
- The specific nature of the chromosomal finding
- Potential implications for future pregnancies
- Available options for prenatal testing in subsequent pregnancies
- Recurrence risks and inheritance patterns
Variants of Uncertain Significance
Sometimes, the test may identify genetic variations whose clinical significance is not yet fully understood. In such cases, our team provides comprehensive counseling and may recommend additional family studies.
Test Pricing and Sample Requirements
| Test Component | Details |
|---|---|
| Test Name | Microarray 60K POC Couple Karyotyping |
| Regular Price | $600 USD |
| Discount Price | $450 USD |
| Turnaround Time | 7-9 days |
| Sample Type | Products of Conception, Peripheral blood of parents |
| Test Components | Sterile Container/Sterile Normal Saline Container for POC and Heparinised vacutainer for parents blood (3 ml) |
Pre-Test Instructions
Microarray 60K POC Couple Karyotyping requires a Doctor’s prescription for most cases. However, prescription requirements do not apply for surgery and pregnancy cases or individuals planning to travel abroad. Our team will guide you through the specific preparation requirements based on your individual circumstances.
Nationwide Availability and Booking
We are proud to offer the Microarray 60K POC Couple Karyotyping test across our extensive network of testing facilities throughout the United States. Our services are available in all major metropolitan areas including:
- New York City and surrounding regions
- Los Angeles and Southern California
- Chicago and the Midwest
- Houston and Texas metropolitan areas
- Phoenix and Arizona regions
- All other major US cities and surrounding communities
Take the Next Step Toward Understanding
If you’re seeking answers about pregnancy loss or concerned about genetic factors affecting your reproductive journey, the Microarray 60K POC Couple Karyotyping test provides the comprehensive analysis you need. Our team of genetic specialists and counselors are ready to support you through every step of the testing process.
Ready to schedule your test or have questions? Contact our genetic counseling team today at +1(267) 388-9828 or book your appointment online. Take control of your reproductive health with advanced genetic insights from General Genetics Corporation.
