Lyme Disease Borrelia Burgdorferi IgG Immunoblot Test
Comprehensive Lyme Disease Diagnostic Testing
The Lyme Disease Borrelia Burgdorferi IgG Immunoblot Test represents a critical advancement in the accurate diagnosis of Lyme disease, a complex tick-borne illness caused by the spirochete bacterium Borrelia burgdorferi. This sophisticated immunoblot methodology provides healthcare providers with definitive evidence of IgG antibody response, which typically develops several weeks after initial infection and persists throughout the disease course.
What This Test Measures and Detects
This specialized immunoblot test detects IgG class antibodies directed against specific Borrelia burgdorferi antigens. Unlike standard ELISA screening tests, the immunoblot technique identifies antibodies to individual bacterial proteins, providing a detailed antibody profile that significantly enhances diagnostic specificity.
- Detects IgG antibodies against Borrelia burgdorferi-specific antigens
- Identifies specific protein bands including OspC, p41, p39, p31, and p93
- Provides confirmation of Lyme disease diagnosis following positive screening tests
- Differentiates between current infection and past exposure
- Helps distinguish true Lyme disease from cross-reactive conditions
Who Should Consider This Test
This advanced diagnostic test is particularly valuable for individuals experiencing persistent symptoms that may indicate Lyme disease, especially those with potential tick exposure in endemic areas.
Key Symptoms and Indications:
- Persistent joint pain and swelling, particularly in large joints
- Neurological symptoms including memory problems, concentration difficulties, and nerve pain
- Chronic fatigue that persists despite adequate rest
- Muscle aches and stiffness without clear explanation
- History of tick bite or outdoor activities in wooded areas
- Previous positive Lyme screening test requiring confirmation
- Unexplained cardiac symptoms or heart rhythm abnormalities
Benefits of Lyme Disease IgG Immunoblot Testing
Choosing the Borrelia Burgdorferi IgG Immunoblot Test provides numerous advantages for accurate diagnosis and appropriate treatment planning.
- Enhanced Diagnostic Accuracy: Superior specificity compared to screening tests reduces false positives
- Definitive Confirmation: Provides conclusive evidence of Lyme disease infection
- Treatment Guidance: Results help physicians determine appropriate antibiotic therapy duration
- Disease Monitoring: Useful for tracking treatment response in chronic cases
- Peace of Mind: Clear results reduce diagnostic uncertainty and anxiety
- Insurance Support: Well-documented test results support insurance claims for treatment
Understanding Your Test Results
Interpreting Lyme disease immunoblot results requires professional medical expertise, but understanding the general principles can help patients better comprehend their diagnosis.
Positive Results:
A positive IgG immunoblot indicates the presence of specific antibodies against Borrelia burgdorferi, confirming exposure to the bacterium. This typically suggests either current active infection or past infection with persistent immune response. Your physician will correlate these findings with clinical symptoms to determine appropriate treatment.
Negative Results:
Negative results suggest that IgG antibodies against Borrelia burgdorferi are not detectable at the time of testing. However, this does not completely rule out Lyme disease, particularly in very early infections before IgG antibodies have developed or in immunocompromised individuals.
Indeterminate Results:
Some tests may show reactivity to only a few bands, falling below the threshold for a positive result. These findings require careful clinical correlation and may warrant repeat testing or additional diagnostic evaluation.
Test Pricing and Availability
| Test Description | Price (USD) |
|---|---|
| Lyme Disease Borrelia Burgdorferi IgG Immunoblot Test – Discount Price | $326 |
| Lyme Disease Borrelia Burgdorferi IgG Immunoblot Test – Regular Price | $476 |
Nationwide Testing Availability
We maintain comprehensive testing facilities across the United States, with convenient locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our network ensures accessible Lyme disease testing regardless of your location.
Take Control of Your Health Today
Don’t let uncertainty about Lyme disease symptoms affect your quality of life. Our advanced IgG Immunoblot testing provides the clarity needed for proper diagnosis and treatment. With rapid turnaround times and expert interpretation, you can get answers and move forward with confidence.
Ready to schedule your Lyme disease test? Contact our dedicated patient services team today at +1(267) 388-9828 or book your appointment online. Our knowledgeable staff will guide you through the testing process and answer any questions you may have about Lyme disease diagnosis and management.
Note: Sample collection must be completed by the 7th of each month, with results typically available within 2-3 weeks. Testing requires 2 mL (1 mL minimum) serum sample collected in SST tube, shipped refrigerated or frozen. A duly filled Test Send Out Consent Form (Form 35) is mandatory for all testing.
