Lyme Disease Borrelia Burgdorferi DNA Qualitative Real Time PCR Test
Comprehensive Introduction to Lyme Disease Detection
Lyme disease represents one of the most significant vector-borne illnesses in the United States, with approximately 30,000 cases reported annually to the CDC. The Borrelia Burgdorferi DNA Qualitative Real Time PCR Test stands as a revolutionary advancement in molecular diagnostics, offering unprecedented accuracy in detecting active Lyme disease infections. This sophisticated testing methodology directly identifies the genetic signature of Borrelia burgdorferi bacteria, providing clinicians with definitive evidence of current infection rather than relying solely on antibody responses that may indicate past exposure.
What This Advanced Test Measures and Detects
Our Real Time PCR test specifically targets and amplifies the unique DNA sequences of Borrelia burgdorferi, the spirochete bacterium responsible for Lyme disease transmission. Unlike traditional serological tests that measure antibody responses, this molecular approach directly detects the presence of bacterial genetic material, offering several critical advantages:
- Direct detection of Borrelia burgdorferi DNA in clinical samples
- Qualitative assessment confirming active infection presence
- High specificity eliminating cross-reactivity with other pathogens
- Superior sensitivity for early-stage infection detection
- Real-time monitoring of DNA amplification for precise quantification
Technical Methodology Explained
The Real Time PCR technology employed in this test utilizes fluorescent probes that bind specifically to Borrelia burgdorferi DNA sequences. As amplification occurs, the fluorescence increases proportionally to the amount of target DNA present, allowing for both detection and semi-quantitative assessment. This method significantly reduces the risk of false positives and provides results with exceptional reliability.
Who Should Consider This Essential Test
This advanced diagnostic test is particularly recommended for individuals presenting with symptoms suggestive of Lyme disease, especially those with potential tick exposure in endemic areas. Key candidates include:
Symptom Presentation Indicators
- Patients with unexplained neurological symptoms including meningitis, cranial neuritis, or radiculoneuritis
- Individuals experiencing persistent joint inflammation or arthritis, particularly in large joints
- Patients with cardiac manifestations such as atrioventricular block or myocarditis
- Those with characteristic erythema migrans rash who seek definitive confirmation
- Individuals with persistent fatigue, cognitive difficulties, or musculoskeletal pain following potential tick exposure
High-Risk Population Considerations
Outdoor workers, hikers, campers, and residents of Lyme-endemic regions including the Northeast, Mid-Atlantic, and Upper Midwest should consider testing if symptoms develop. Early testing is crucial for preventing progression to late-stage complications.
Significant Benefits of Advanced PCR Testing
Choosing the Borrelia Burgdorferi DNA PCR Test provides numerous advantages over conventional diagnostic approaches:
Clinical Accuracy Advantages
- Early Detection Capability: Identifies infection before antibody development, enabling prompt treatment initiation
- Definitive Diagnosis: Direct pathogen detection eliminates ambiguity in interpretation
- Treatment Guidance: Confirms active infection requiring antimicrobial therapy
- Monitoring Tool: Can assess treatment response in complicated cases
Patient-Centered Benefits
- Avoids unnecessary antibiotic trials through precise diagnosis
- Reduces diagnostic uncertainty and patient anxiety
- Facilitates appropriate specialist referral when indicated
- Supports comprehensive management of persistent symptoms
Understanding Your Test Results
Proper interpretation of your Borrelia Burgdorferi DNA PCR results is essential for appropriate clinical management:
Result Interpretation Guidelines
- Positive Result: Indicates detection of Borrelia burgdorferi DNA, confirming active Lyme disease infection requiring appropriate antibiotic therapy
- Negative Result: Suggests absence of detectable bacterial DNA in the tested sample; does not completely rule out infection if sampling occurred during low bacteremia periods
- Indeterminate Result: May require repeat testing or additional diagnostic evaluation
Clinical Correlation Importance
Test results should always be interpreted in the context of clinical presentation, exposure history, and supporting laboratory findings. A negative PCR result in the presence of strong clinical suspicion may warrant additional testing modalities or repeat evaluation.
Test Pricing and Service Details
| Test Description | Regular Price | Discount Price |
|---|---|---|
| Lyme Disease Borrelia Burgdorferi DNA Qualitative Real Time PCR Test | $950 USD | $750 USD |
Service Specifications
- Turnaround Time: Sample by 7th of the month; Report available after 2-3 weeks
- Sample Type: 2 mL (1 mL minimum) CSF or Synovial Fluid in sterile screw-capped container
- Shipping Requirements: Refrigerated or frozen transport
- Mandatory Documentation: Duly filled Test Send Out Consent Form (Form 35)
Nationwide Accessibility and Convenience
General Genetics Corporation maintains comprehensive testing facilities across the United States, ensuring convenient access to advanced Lyme disease diagnostics. Our network includes specialized collection centers in major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Each facility adheres to strict quality standards and employs trained phlebotomists experienced in specialized sample collection.
Take Action Against Lyme Disease Today
Don’t let diagnostic uncertainty delay your path to recovery. Our Borrelia Burgdorferi DNA PCR Test provides the definitive answers you need for appropriate Lyme disease management. With our discounted price of $750 USD, advanced molecular diagnostics are more accessible than ever.
Ready to schedule your test? Contact our dedicated patient services team today:
Phone: +1(267) 388-9828
Our representatives are available to answer your questions, assist with scheduling, and provide guidance on sample collection requirements. Take the first step toward accurate diagnosis and effective treatment – call now to book your Borrelia Burgdorferi DNA Qualitative Real Time PCR Test.
