Lung Cancer Panel 5 (EGFR, KRAS, BRAF, ALK1, ROS1) Comprehensive Genetic Analysis
Understanding Lung Cancer Genetic Testing
Lung cancer remains one of the most prevalent and challenging cancers worldwide, but recent advances in genetic testing have revolutionized treatment approaches. The Lung Cancer Panel 5 represents a cutting-edge molecular diagnostic tool that analyzes five critical genes known to drive lung cancer progression. This comprehensive panel provides oncologists with essential information to develop personalized treatment strategies based on your tumor’s unique genetic profile.
What Does the Lung Cancer Panel 5 Test Measure?
Our advanced genetic panel specifically targets mutations in five key genes that play crucial roles in lung cancer development and progression:
EGFR (Epidermal Growth Factor Receptor)
EGFR mutations are among the most common genetic alterations in non-small cell lung cancer (NSCLC). These mutations can make cancer cells grow and divide more rapidly. Identifying EGFR mutations is particularly important because they often respond well to targeted therapies called EGFR inhibitors.
KRAS (Kirsten Rat Sarcoma Viral Oncogene Homolog)
KRAS mutations are frequently found in lung adenocarcinoma and can indicate resistance to certain targeted therapies. Understanding KRAS status helps oncologists avoid ineffective treatments and explore alternative options.
BRAF (B-Raf Proto-Oncogene)
BRAF mutations, while less common in lung cancer, can be effectively targeted with specific inhibitors. Detection of BRAF mutations opens up additional treatment possibilities for patients who may not respond to standard therapies.
ALK1 (Anaplastic Lymphoma Kinase)
ALK rearrangements occur when the ALK gene fuses with another gene, creating an abnormal protein that promotes cancer growth. Patients with ALK-positive lung cancer often respond exceptionally well to ALK inhibitors.
ROS1 (ROS Proto-Oncogene 1)
ROS1 gene rearrangements, similar to ALK alterations, create fusion proteins that drive cancer growth. Identifying ROS1 positivity enables treatment with targeted therapies specifically designed for this genetic profile.
Who Should Consider This Genetic Testing?
This comprehensive lung cancer panel is recommended for individuals who:
- Have been diagnosed with non-small cell lung cancer (NSCLC)
- Are experiencing persistent respiratory symptoms including chronic cough, shortness of breath, or chest pain
- Have unexplained weight loss, fatigue, or recurrent respiratory infections
- Have a family history of lung cancer or genetic predisposition
- Are current or former heavy smokers with concerning symptoms
- Need guidance on targeted therapy options after initial diagnosis
- Are considering participation in clinical trials for lung cancer treatment
Key Benefits of Lung Cancer Panel 5 Testing
Undergoing comprehensive genetic testing provides numerous advantages for lung cancer patients:
Personalized Treatment Planning
By identifying specific genetic mutations, your oncology team can select targeted therapies that directly address the molecular drivers of your cancer, potentially leading to better outcomes and fewer side effects.
Improved Treatment Efficacy
Targeted therapies designed for specific genetic alterations often demonstrate higher response rates compared to traditional chemotherapy, with potentially reduced toxicity.
Informed Clinical Trial Eligibility
Genetic testing results can identify eligibility for cutting-edge clinical trials exploring new targeted treatments and immunotherapies.
Comprehensive Mutation Profiling
Testing multiple genes simultaneously provides a complete picture of your tumor’s genetic landscape, enabling comprehensive treatment strategy development.
Understanding Your Test Results
Your Lung Cancer Panel 5 results will provide detailed information about the genetic mutations detected in your tumor sample. Our genetic counselors and oncology specialists will help you understand what these results mean for your treatment options:
Positive Results
If mutations are detected in any of the five genes tested, this indicates that targeted therapies may be effective options. Your oncology team will discuss specific treatment recommendations based on the identified mutations.
Negative Results
If no mutations are detected in the tested genes, this information is still valuable as it helps rule out certain targeted therapy options, allowing your medical team to focus on other effective treatment strategies.
Variant of Unknown Significance
In some cases, genetic changes may be identified whose clinical significance is not yet fully understood. Our team will provide guidance on how to interpret these findings and any additional testing that may be recommended.
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | Lung Cancer Panel 5 (EGFR, KRAS, BRAF, ALK1, ROS1) |
| Regular Price | $1200 USD |
| Discount Price | $900 USD |
| Turnaround Time | 5-7 days |
| Sample Type | Tumor tissue (paraffin embedded tissue blocks) |
| Testing Methods | FISH, Sanger Sequencing |
| Specialty | Oncology Genetics |
Pre-Test Instructions and Requirements
The Lung Cancer Panel 5 requires a Doctor’s prescription for testing. Please note that prescriptions are not applicable for surgery and pregnancy cases, or for individuals planning to travel abroad. Our team will guide you through the sample collection process and ensure proper handling of your tumor tissue samples.
Nationwide Testing Availability
We have testing facilities and branches across all major cities in the United States, including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our nationwide network ensures convenient access to advanced genetic testing regardless of your location.
Take Control of Your Lung Cancer Journey
Understanding your lung cancer’s genetic profile is the first step toward personalized, effective treatment. Our comprehensive Lung Cancer Panel 5 provides the critical information needed to make informed decisions about your care. With rapid 5-7 day turnaround times and expert genetic counseling support, we’re committed to helping you navigate your treatment options with confidence.
Ready to Get Started?
Don’t wait to get the answers you need. Contact our genetic specialists today to schedule your Lung Cancer Panel 5 test and take the first step toward personalized cancer care.
Call or WhatsApp us now: +1(267) 388-9828
Our team is available to answer your questions, discuss insurance coverage options, and help you begin the testing process. Early genetic testing can make a significant difference in your treatment outcomes and quality of life.
