Liver Kidney Microsomal LKM Antibody IFA Test
Understanding the LKM Antibody Test
The Liver Kidney Microsomal (LKM) Antibody IFA Test represents a critical advancement in autoimmune liver disease diagnostics. This specialized immunopathology test detects antibodies that specifically target the cytochrome P450 2D6 enzyme system found in liver and kidney microsomes. The presence of LKM-1 antibodies is strongly associated with autoimmune hepatitis type 2, a serious condition where the body’s immune system mistakenly attacks healthy liver cells.
What Does This Test Measure?
The LKM Antibody IFA Test utilizes Immunofluorescence Assay technology to identify and quantify LKM-1 antibodies in patient serum. These antibodies are directed against the cytochrome P450 2D6 enzyme, which plays a crucial role in drug metabolism. The test provides:
- Detection of LKM-1 antibodies specific to autoimmune hepatitis type 2
- Differentiation between various types of autoimmune liver diseases
- Quantitative assessment of antibody levels for monitoring disease progression
- Identification of autoimmune hepatitis in patients with unexplained liver inflammation
Who Should Consider This Test?
This test is particularly important for individuals experiencing symptoms suggestive of autoimmune liver disease. Consider the LKM Antibody Test if you have:
- Unexplained elevated liver enzymes (ALT, AST)
- Persistent fatigue and weakness
- Jaundice (yellowing of skin and eyes)
- Abdominal discomfort or pain in the upper right quadrant
- Family history of autoimmune disorders
- Previous diagnosis of other autoimmune conditions
- Unexplained liver inflammation without viral hepatitis markers
Clinical Indications and Symptoms
Patients presenting with autoimmune hepatitis often experience a range of symptoms that may develop gradually or appear suddenly. Early detection through the LKM Antibody Test can prevent serious complications including cirrhosis and liver failure. The test is especially valuable for young women and children, as autoimmune hepatitis type 2 frequently affects these populations.
Benefits of Taking the LKM Antibody Test
Early diagnosis through the LKM Antibody IFA Test offers numerous advantages for patient care and treatment outcomes:
- Accurate Diagnosis: Provides definitive identification of autoimmune hepatitis type 2
- Early Intervention: Enables prompt treatment before significant liver damage occurs
- Treatment Guidance: Helps gastroenterologists develop targeted immunosuppressive therapy plans
- Disease Monitoring: Allows tracking of treatment effectiveness and disease progression
- Differential Diagnosis: Distinguishes autoimmune hepatitis from other liver conditions
- Prevention of Complications: Reduces risk of cirrhosis and liver transplantation needs
Understanding Your Test Results
Interpreting LKM Antibody Test results requires professional medical expertise, but here’s general guidance:
Positive Results
A positive LKM Antibody test indicates the presence of LKM-1 antibodies, strongly suggesting autoimmune hepatitis type 2. Your gastroenterologist will typically:
- Correlate results with clinical symptoms and other liver function tests
- Initiate appropriate immunosuppressive therapy
- Schedule regular monitoring of liver function and antibody levels
- Consider additional testing to rule out other autoimmune conditions
Negative Results
Negative results suggest the absence of LKM-1 antibodies, but don’t completely rule out autoimmune liver disease. Your healthcare provider may:
- Investigate other causes of liver inflammation
- Consider testing for other autoimmune markers (ANA, SMA)
- Evaluate for viral hepatitis or metabolic liver diseases
- Monitor symptoms and repeat testing if clinical suspicion remains high
Test Details and Pricing
| Test Parameter | Details |
|---|---|
| Test Name | Liver Kidney Microsomal LKM Antibody IFA Test |
| Discount Price | $46 USD |
| Regular Price | $52 USD |
| Sample Type | 2 mL (1 mL min.) serum from 1 SST |
| Sample Handling | Ship refrigerated or frozen |
| Turnaround Time | Same day (when sample collected by 9 AM) |
| Preparation | No special preparation required |
| Methodology | Immunofluorescence Assay (IFA) |
Nationwide Availability
We have diagnostic centers conveniently located across the United States, serving major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art facilities ensure consistent, reliable testing with rapid turnaround times.
Take Control of Your Liver Health Today
Don’t wait for symptoms to worsen. Early detection of autoimmune hepatitis through the LKM Antibody Test can significantly improve treatment outcomes and quality of life. Our experienced team is ready to assist you with convenient testing and comprehensive result interpretation.
Book your Liver Kidney Microsomal LKM Antibody IFA Test today by calling +1(267) 388-9828 or visiting our website to schedule your appointment. Take the first step toward understanding your liver health with this essential diagnostic tool.
