LHX3 Gene Pituitary Hormone Deficiency Combined Type 3 NGS Genetic DNA Test
Comprehensive Genetic Testing for Pituitary Hormone Disorders
The LHX3 Gene Pituitary Hormone Deficiency Combined Type 3 NGS Genetic DNA Test represents a breakthrough in endocrine genetic diagnostics. This advanced test specifically targets the LHX3 gene, which plays a crucial role in pituitary gland development and hormone regulation. Using state-of-the-art Next-Generation Sequencing technology, our test provides unparalleled accuracy in detecting genetic mutations that cause combined pituitary hormone deficiency type 3.
What Does This Test Measure and Detect?
This comprehensive genetic analysis examines the LHX3 gene for mutations that disrupt normal pituitary function. The test specifically identifies:
- Point mutations in the LHX3 gene coding regions
- Deletions and insertions affecting gene function
- Regulatory region variations impacting gene expression
- Compound heterozygous mutations
- Autosomal recessive inheritance patterns
The LHX3 gene encodes a transcription factor essential for proper development of anterior pituitary cells that produce growth hormone, prolactin, thyroid-stimulating hormone, and gonadotropins. Mutations in this gene lead to combined deficiencies of these critical hormones.
Who Should Consider This Genetic Test?
This test is recommended for individuals presenting with:
- Growth Failure: Children with significant short stature and growth retardation
- Delayed Puberty: Adolescents experiencing delayed sexual development
- Thyroid Dysfunction: Unexplained hypothyroidism with normal thyroid gland
- Adrenal Insufficiency: Low cortisol levels and adrenal crisis symptoms
- Family History: Individuals with relatives diagnosed with pituitary disorders
- Multiple Hormone Deficiencies: Patients with combined deficiencies of GH, TSH, LH, FSH, or prolactin
- Neonatal Hypoglycemia: Infants with recurrent low blood sugar episodes
Clinical Benefits of LHX3 Genetic Testing
Undergoing this genetic test provides numerous clinical advantages:
- Precise Diagnosis: Confirms genetic basis of hormone deficiencies
- Personalized Treatment: Enables targeted hormone replacement therapy
- Family Planning: Provides genetic counseling information for future generations
- Early Intervention: Allows proactive management before complications develop
- Comprehensive Care: Guides multidisciplinary treatment approach
- Prognostic Information: Helps predict disease progression and outcomes
Understanding Your Test Results
Our genetic counselors provide comprehensive interpretation of your results:
- Positive Result: Confirms LHX3 gene mutation and diagnosis of combined pituitary hormone deficiency type 3
- Negative Result: Rules out LHX3 mutations, suggesting alternative causes for hormone deficiencies
- Variant of Uncertain Significance: Identifies genetic changes requiring further clinical correlation
- Carrier Status: Determines if you carry a single copy of mutated gene
All positive results include detailed recommendations for hormone replacement therapy, monitoring protocols, and specialist referrals.
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Nationwide Testing Availability
We have diagnostic centers conveniently located throughout the United States, including major metropolitan areas such as New York City, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our state-of-the-art facilities ensure accurate sample collection and processing.
Take Control of Your Endocrine Health Today
Don’t let unexplained hormone deficiencies impact your quality of life. Our LHX3 Genetic DNA Test provides the answers you need for proper diagnosis and treatment. With results available in 3-4 weeks and multiple sample collection options including blood, extracted DNA, or blood spot cards, getting tested has never been more convenient.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic counseling session and book your test. Our expert genetic counselors are ready to help you understand your risk and guide you through the testing process.
Remember to bring your clinical history and be prepared for a genetic counseling session to create a detailed family pedigree chart. Early diagnosis through genetic testing can significantly improve treatment outcomes and quality of life for individuals with combined pituitary hormone deficiencies.
