LHCGR Gene Leydig Cell Hypoplasia Type 1 NGS Genetic DNA Test
Comprehensive Genetic Testing for Reproductive Health
The LHCGR Gene Leydig Cell Hypoplasia Type 1 NGS Genetic DNA Test represents a cutting-edge diagnostic approach for identifying genetic mutations associated with reproductive disorders. This specialized test focuses on the LHCGR (luteinizing hormone/choriogonadotropin receptor) gene, which plays a crucial role in male sexual development and reproductive function.
What is Leydig Cell Hypoplasia Type 1?
Leydig cell hypoplasia type 1 is a rare autosomal recessive disorder characterized by impaired male sexual development due to mutations in the LHCGR gene. This condition affects the development and function of Leydig cells in the testes, which are responsible for testosterone production. Without proper testosterone signaling, individuals may experience incomplete masculinization and reproductive challenges.
What the Test Measures and Detects
Our advanced NGS Genetic DNA Test specifically targets the LHCGR gene to identify:
- Point mutations affecting receptor function
- Frameshift mutations disrupting protein structure
- Nonsense mutations leading to premature stop codons
- Missense mutations altering receptor binding capacity
- Deletions and insertions affecting gene integrity
The test utilizes Next-Generation Sequencing technology to provide comprehensive coverage of the entire LHCGR gene coding region, ensuring high sensitivity and specificity in mutation detection.
Who Should Consider This Test
Clinical Indications and Symptoms
This genetic test is recommended for individuals presenting with:
- Delayed or absent puberty in males
- Ambiguous genitalia at birth
- Micropenis or underdeveloped male genitalia
- Primary amenorrhea in genetic males
- Infertility with suspected endocrine causes
- Family history of reproductive disorders
- Elevated luteinizing hormone levels with low testosterone
- Suspected disorders of sexual development
Benefits of Taking the LHCGR Genetic Test
Undergoing this comprehensive genetic analysis provides numerous advantages:
- Accurate Diagnosis: Confirms or rules out LHCGR gene mutations with high precision
- Personalized Treatment: Guides hormone therapy and medical management decisions
- Genetic Counseling: Provides essential information for family planning
- Early Intervention: Enables timely medical care for affected individuals
- Reproductive Planning: Informs decisions about fertility preservation and options
- Psychological Support: Helps individuals and families understand their condition
Understanding Your Test Results
Interpretation Guidance
Your test results will be carefully analyzed and interpreted by our team of genetic specialists:
Positive Result: Identification of pathogenic mutations in the LHCGR gene confirms the diagnosis of Leydig cell hypoplasia type 1. This result provides definitive evidence for the genetic basis of reproductive symptoms and guides appropriate medical management.
Negative Result: Absence of known pathogenic mutations suggests that LHCGR gene abnormalities are not the cause of the clinical presentation. However, further evaluation for other genetic or endocrine disorders may be recommended.
Variant of Uncertain Significance: Some genetic changes may have unknown clinical implications. Our genetic counseling team will provide guidance on the significance of these findings and recommend appropriate follow-up.
Test Information and Pricing
| Test Feature | Details |
|---|---|
| Test Name | LHCGR Gene Leydig Cell Hypoplasia Type 1 NGS Genetic DNA Test |
| Regular Price | $700 USD |
| Discount Price | $500 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
| Specialty | Gynecology and Reproductive Medicine |
| Department | Genetics |
Pre-Test Requirements
Before scheduling your test, please ensure:
- Complete clinical history of the patient
- Genetic counseling session to create a family pedigree chart
- Documentation of family members affected by reproductive disorders
- Review of previous endocrine testing results
Nationwide Testing Availability
We have testing facilities conveniently located across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network of certified laboratories ensures consistent, high-quality testing standards nationwide.
Take Control of Your Reproductive Health
Don’t let uncertainty about reproductive health concerns affect your quality of life. Our LHCGR Gene Leydig Cell Hypoplasia Type 1 NGS Genetic DNA Test provides the clarity and answers you need for informed medical decisions and family planning.
Ready to schedule your test? Contact our genetic specialists today at +1(267) 388-9828 or book your appointment online. Our team is available to answer your questions and guide you through the testing process with compassion and expertise.
Take the first step toward understanding your genetic health and reproductive future. Book your comprehensive genetic assessment now and benefit from our current promotional pricing of only $500 USD.
