Leucocyte Alkaline Phosphatase Score LAP Score Test
Understanding the Leucocyte Alkaline Phosphatase Score Test
The Leucocyte Alkaline Phosphatase Score (LAP Score) Test represents a sophisticated cytochemistry-based diagnostic procedure that evaluates the enzymatic activity of alkaline phosphatase within white blood cells, specifically neutrophils. This specialized hematological examination provides crucial insights into bone marrow function and helps differentiate between various blood disorders affecting leukocyte production and maturation.
What Does the LAP Score Test Measure?
The LAP Score Test precisely quantifies the alkaline phosphatase enzyme activity present in the cytoplasm of mature neutrophils. This enzyme plays a vital role in cellular metabolism and its activity levels serve as important markers for distinguishing between:
- Reactive leukocytosis (increased white blood cell count due to infection or inflammation)
- Chronic myeloid leukemia and other myeloproliferative disorders
- Bone marrow stress responses versus malignant transformations
- Various hematological conditions affecting granulocyte function
Who Should Consider This Test?
This specialized hematology test is recommended for individuals experiencing symptoms that may indicate underlying bone marrow or blood cell disorders. Consult your healthcare provider about the LAP Score Test if you experience:
- Unexplained fatigue and weakness persisting for weeks
- Recurrent infections or slow healing
- Unexplained bruising or bleeding tendencies
- Enlarged lymph nodes or spleen
- Abnormal complete blood count (CBC) results
- Night sweats and unexplained weight loss
- Bone pain or tenderness
Clinical Indications for Testing
Hematologists and physicians typically order the LAP Score Test when investigating:
- Suspected chronic myeloid leukemia (CML) differentiation
- Polycythemia vera diagnosis and monitoring
- Essential thrombocythemia evaluation
- Reactive leukocytosis assessment
- Myelofibrosis investigation
- Leukemoid reactions differentiation
Benefits of the LAP Score Test
Choosing the Leucocyte Alkaline Phosphatase Score Test offers multiple advantages for comprehensive hematological assessment:
- Accurate Differentiation: Helps distinguish between benign reactive conditions and malignant blood disorders
- Diagnostic Precision: Provides specific markers for chronic myeloid leukemia identification
- Treatment Guidance: Assists hematologists in developing targeted treatment strategies
- Monitoring Tool: Enables tracking of disease progression and treatment response
- Cost-Effective: Affordable testing at only $24 provides significant diagnostic value
- Non-Invasive Sample: Requires only blood smears with minimal patient discomfort
Understanding Your Test Results
Interpreting LAP Score results requires professional medical expertise, but general guidance includes:
Normal LAP Score Range
Typically, normal LAP scores range between 20-100, though reference values may vary slightly between laboratories. Normal scores generally indicate:
- Healthy bone marrow function
- Appropriate neutrophil maturation
- Absence of specific myeloproliferative disorders
Elevated LAP Score
Increased LAP scores (above normal range) may suggest:
- Reactive leukocytosis from infections or inflammation
- Polycythemia vera
- Essential thrombocythemia
- Myelofibrosis
- Leukemoid reactions
- Pregnancy-related changes
Decreased LAP Score
Reduced LAP scores (below normal range) often indicate:
- Chronic myeloid leukemia (CML)
- Paroxysmal nocturnal hemoglobinuria
- Certain types of acute leukemia
- Aplastic anemia in some cases
Test Procedure and Sample Requirements
The LAP Score Test requires specific sample preparation for accurate results:
- Sample Type: 5 fresh blood smears from finger prick
- Fixation: Fixed in 95% ethanol for 30 minutes
- Processing: Air dry and ship immediately at room temperature
- Turnaround Time: Results typically available within 1 week
- Preparation: No special preparation required
Test Pricing Information
| Test Name | Discount Price | Regular Price |
|---|---|---|
| Leucocyte Alkaline Phosphatase Score LAP Score Test | $24 USD | $26 USD |
Nationwide Testing Availability
GGC DNA provides comprehensive Leucocyte Alkaline Phosphatase Score testing services across the United States. Our state-of-the-art laboratories and collection centers are conveniently located in major metropolitan areas including:
- New York City and surrounding areas
- Los Angeles and Southern California
- Chicago and Midwest regions
- Houston and Texas locations
- Phoenix and Arizona facilities
- Philadelphia and Northeast centers
Book Your Test Today
Take control of your hematological health with our comprehensive LAP Score testing. Our experienced team ensures accurate results and professional service. For appointments or questions, contact us at:
Phone/WhatsApp: +1(267) 388-9828
Schedule your Leucocyte Alkaline Phosphatase Score Test today and receive your results within one week. Our dedicated hematology specialists are available to discuss your testing needs and provide guidance throughout the process.
