KNL1 Gene Microcephaly Autosomal Recessive Type 4 NGS Genetic DNA Test
Comprehensive Genetic Testing for Microcephaly
The KNL1 Gene Microcephaly Autosomal Recessive Type 4 NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for neurological disorders. This specialized test utilizes cutting-edge next-generation sequencing (NGS) technology to identify mutations in the KNL1 gene, which plays a critical role in brain development and cell division. Microcephaly, characterized by an abnormally small head circumference, can have significant implications for neurological development and overall health.
What This Test Measures and Detects
This comprehensive genetic analysis specifically targets the KNL1 gene, which encodes the kinetochore null protein 1 essential for proper chromosome segregation during cell division. The test detects:
- Pathogenic variants and mutations in the KNL1 gene
- Single nucleotide polymorphisms (SNPs) associated with microcephaly
- Insertions, deletions, and copy number variations
- Compound heterozygous mutations in autosomal recessive inheritance patterns
- Novel variants that may contribute to microcephaly development
Who Should Consider This Genetic Test
This test is particularly recommended for individuals presenting with:
- Unexplained microcephaly (head circumference below the 3rd percentile)
- Developmental delays and intellectual disability
- Neurological symptoms including seizures or motor coordination issues
- Family history of microcephaly or related neurological conditions
- Consanguineous parentage with neurological concerns in offspring
- Previous pregnancies affected by microcephaly or brain development abnormalities
Key Benefits of KNL1 Genetic Testing
Undergoing this comprehensive genetic analysis provides numerous advantages:
- Accurate Diagnosis: Confirms or rules out KNL1-related microcephaly with high precision
- Family Planning Guidance: Provides essential information for future reproductive decisions
- Early Intervention: Enables timely implementation of developmental support services
- Medical Management: Guides appropriate treatment and monitoring strategies
- Genetic Counseling: Supports informed decision-making for affected families
- Research Contribution: Advances understanding of microcephaly genetics
Understanding Your Test Results
Your genetic test results will be carefully interpreted by our expert geneticists and presented with comprehensive guidance:
- Positive Result: Indicates the presence of pathogenic KNL1 mutations, confirming diagnosis of autosomal recessive microcephaly type 4
- Negative Result: Suggests that KNL1 mutations are not the cause of microcephaly, prompting investigation of other genetic factors
- Variant of Uncertain Significance: Identifies genetic changes whose clinical significance requires further investigation
- Carrier Status: Determines if individuals carry one copy of a mutated gene without showing symptoms
All results include detailed interpretation and recommendations for next steps, with genetic counseling available to help you understand the implications for your family.
Test Pricing and Details
| Test Feature | Details |
|---|---|
| Test Name | KNL1 Gene Microcephaly Autosomal Recessive Type 4 NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Nationwide Testing Availability
We proudly offer comprehensive genetic testing services across the United States, with convenient locations in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art laboratories ensure consistent, high-quality results regardless of your location.
Take the Next Step Toward Genetic Clarity
If you or your family are experiencing concerns related to microcephaly or neurological development, the KNL1 Gene Microcephaly Autosomal Recessive Type 4 NGS Genetic DNA Test provides the answers you need. Our team of genetic specialists is ready to support you through every step of the testing process, from initial consultation to result interpretation and beyond.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic test consultation and take the first step toward understanding your genetic health.
