KCNJ5 Gene Long QT Syndrome Type 13 NGS Genetic DNA Test
Comprehensive Genetic Testing for Inherited Cardiac Conditions
The KCNJ5 Gene Long QT Syndrome Type 13 NGS Genetic DNA Test represents a breakthrough in cardiovascular genetic diagnostics, offering precise detection of mutations associated with Long QT Syndrome Type 13. This specialized test provides critical information for individuals and families affected by inherited heart rhythm disorders, enabling early intervention and personalized treatment strategies.
What Does This Test Measure?
This advanced genetic test specifically analyzes the KCNJ5 gene using Next-Generation Sequencing (NGS) technology to identify mutations that cause Long QT Syndrome Type 13. The KCNJ5 gene encodes the potassium inwardly-rectifying channel subfamily J member 5, which plays a crucial role in maintaining proper electrical activity in heart cells. Mutations in this gene disrupt normal potassium channel function, leading to prolonged QT intervals on electrocardiograms and increased risk of dangerous arrhythmias.
- Comprehensive analysis of the entire KCNJ5 gene coding region
- Detection of point mutations, insertions, and deletions
- Identification of both inherited and de novo genetic variations
- Assessment of variant pathogenicity and clinical significance
Who Should Consider This Test?
This genetic test is recommended for individuals displaying symptoms or having risk factors associated with Long QT Syndrome:
- Patients with unexplained syncope (fainting spells)
- Individuals with family history of sudden cardiac death
- Those with documented prolonged QT interval on ECG
- Patients experiencing seizures triggered by emotional stress or exercise
- Individuals with hearing loss and cardiac symptoms (Jervell and Lange-Nielsen syndrome)
- Family members of individuals diagnosed with Long QT Syndrome
- Infants and children with abnormal cardiac rhythms
Clinical Benefits of Genetic Testing
Undergoing the KCNJ5 Gene Long QT Syndrome Type 13 NGS Genetic DNA Test provides numerous clinical advantages:
- Accurate Diagnosis: Confirms or rules out genetic causes of cardiac symptoms
- Family Screening: Enables targeted testing of at-risk family members
- Personalized Treatment: Guides medication selection and lifestyle recommendations
- Risk Stratification: Helps determine the need for implantable devices
- Reproductive Planning: Provides information for family planning decisions
- Early Intervention: Allows for preventive measures before symptoms develop
Understanding Your Test Results
Your genetic test results will fall into one of several categories, each with specific clinical implications:
- Positive Result: A pathogenic mutation is identified, confirming Long QT Syndrome Type 13 diagnosis and guiding specific treatment approaches
- Negative Result: No known disease-causing mutations detected, though clinical monitoring may still be recommended based on symptoms
- Variant of Uncertain Significance (VUS): A genetic change is identified whose clinical significance is currently unknown, requiring ongoing research and family studies
- Benign Variant: Genetic changes that do not increase disease risk
All results are accompanied by comprehensive genetic counseling to ensure proper understanding and appropriate next steps.
Test Pricing and Details
| Test Component | Details |
|---|---|
| Test Name | KCNJ5 Gene Long QT Syndrome Type 13 NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Pre-Test Requirements
Before undergoing testing, patients should provide:
- Complete clinical history including cardiac symptoms and family medical background
- Participation in genetic counseling session to create detailed family pedigree
- Documentation of any previous cardiac testing or evaluations
- Informed consent for genetic testing and potential implications
Nationwide Testing Availability
We have diagnostic centers conveniently located across the United States, serving patients in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art facilities ensure consistent, high-quality testing standards nationwide.
Take Control of Your Cardiac Health Today
Don’t let uncertainty about inherited cardiac conditions affect your quality of life. The KCNJ5 Gene Long QT Syndrome Type 13 NGS Genetic DNA Test provides the clarity needed for informed medical decisions and proactive health management. Our team of genetic counselors and cardiac specialists are available to guide you through the testing process and help interpret your results.
Ready to schedule your genetic test? Call our dedicated cardiac genetics team today at +1(267) 388-9828 or book your appointment online. Take the first step toward understanding your genetic cardiac risk and protecting your heart health for years to come.
