KCNE2 Gene Atrial Fibrillation Type 4 NGS Genetic DNA Test
Comprehensive Genetic Analysis for Inherited Cardiac Arrhythmias
The KCNE2 Gene Atrial Fibrillation Type 4 NGS Genetic DNA Test represents a breakthrough in cardiovascular genetic testing, offering precise detection of mutations associated with familial atrial fibrillation. This sophisticated diagnostic tool utilizes advanced Next-Generation Sequencing technology to analyze the KCNE2 gene, which plays a critical role in regulating cardiac electrical activity and maintaining normal heart rhythm.
What Does This Test Measure?
This specialized genetic test specifically targets the KCNE2 gene, which encodes the MinK-related peptide 1 protein that modulates potassium channel function in cardiac cells. The test identifies:
- Pathogenic variants in the KCNE2 gene associated with atrial fibrillation type 4
- Single nucleotide polymorphisms (SNPs) affecting cardiac ion channel regulation
- Genetic mutations that disrupt normal electrical conduction in the heart
- Inherited variations that increase susceptibility to arrhythmias
- Specific genetic markers linked to early-onset atrial fibrillation
Who Should Consider This Test?
This genetic analysis is particularly valuable for individuals experiencing:
- Unexplained palpitations or irregular heartbeats
- Family history of atrial fibrillation or sudden cardiac death
- Early-onset atrial fibrillation (before age 60)
- Recurrent cardiac arrhythmias without clear structural heart disease
- Multiple family members with similar cardiac rhythm disorders
- Unexplained syncope or fainting episodes
- Young individuals with atrial fibrillation and no traditional risk factors
Clinical Benefits of Genetic Testing
Undergoing the KCNE2 genetic test provides numerous advantages for cardiac care management:
- Early Risk Identification: Detect genetic predisposition before symptom onset
- Personalized Treatment Planning: Guide medication selection and dosage based on genetic profile
- Family Screening Opportunities: Identify at-risk relatives for proactive monitoring
- Improved Diagnostic Accuracy: Confirm underlying genetic causes of cardiac symptoms
- Enhanced Risk Stratification: Better predict disease progression and complications
- Informed Lifestyle Decisions: Make educated choices about exercise, diet, and stress management
Understanding Your Test Results
Your genetic test results will fall into one of several categories, each with specific implications:
- Positive Result: Indicates the presence of a known pathogenic variant in the KCNE2 gene. This confirms genetic predisposition to atrial fibrillation type 4 and warrants regular cardiac monitoring and potential preventive treatments.
- Negative Result: No known pathogenic variants detected. While reassuring, this doesn’t completely eliminate atrial fibrillation risk, as other genetic or environmental factors may contribute.
- Variant of Uncertain Significance (VUS): Identifies a genetic change with unknown clinical impact. Regular follow-up and family studies may help clarify significance over time.
- Complex Results: Multiple genetic variations detected, requiring comprehensive interpretation by genetic specialists and cardiologists.
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Turnaround Time: 3 to 4 Weeks
Sample Type: Blood, Extracted DNA, or One Drop Blood on FTA Card
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified genetic counselors and cardiology specialists ensures comprehensive care coordination regardless of your location.
Pre-Test Preparation and Genetic Counseling
Before undergoing testing, we recommend:
- Comprehensive clinical history documentation
- Genetic counseling session with our certified specialists
- Development of detailed family pedigree chart
- Discussion of potential results and their implications
- Understanding insurance coverage and out-of-pocket costs
- Planning for result disclosure and follow-up care
Take Control of Your Cardiac Health Today
Don’t wait for symptoms to escalate. Early genetic detection of KCNE2 mutations can significantly impact your cardiac health management and potentially prevent serious complications. Our team of genetic specialists and cardiologists are ready to guide you through the testing process and help interpret your results within the context of your overall health profile.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic counseling session and book your KCNE2 Gene Atrial Fibrillation Type 4 NGS Genetic DNA Test. Take the first step toward personalized cardiac care and peace of mind.

