JAM3 Gene Hemorrhagic Destruction of the Brain, Subependymal Calcification, and Cataracts NGS Genetic DNA Test
Comprehensive Genetic Testing for Rare Neurological Conditions
The JAM3 Gene NGS Genetic DNA Test represents a breakthrough in diagnostic precision for individuals and families affected by rare neurological disorders. This advanced genetic analysis specifically targets mutations in the Junctional Adhesion Molecule 3 (JAM3) gene, which plays a critical role in maintaining the integrity of the blood-brain barrier and vascular development. When mutations occur in this gene, they can lead to a devastating constellation of symptoms including brain hemorrhages, abnormal calcium deposits in brain tissue, and early-onset cataracts.
What This Test Measures and Detects
Our comprehensive NGS (Next-Generation Sequencing) test provides detailed analysis of the JAM3 gene to identify:
- Pathogenic variants and mutations in the JAM3 gene sequence
- Single nucleotide polymorphisms (SNPs) associated with disease manifestation
- Copy number variations that may affect gene function
- Deletion and duplication events impacting protein structure
- Inheritance patterns (autosomal recessive) for family planning
The test utilizes cutting-edge NGS technology to examine the entire coding region of the JAM3 gene, ensuring comprehensive coverage and accurate detection of even rare genetic variants that might be missed by conventional testing methods.
Who Should Consider This Genetic Test
This specialized genetic testing is particularly recommended for individuals presenting with the following symptoms or clinical scenarios:
- Infants and children with unexplained intracranial hemorrhages
- Patients with subependymal calcification detected on brain imaging
- Individuals with congenital or early-onset cataracts
- Children experiencing developmental delays or neurological regression
- Families with a history of similar neurological conditions
- Parents planning future pregnancies after having an affected child
- Individuals with suspected vascular brain disorders of unknown origin
Significant Benefits of JAM3 Genetic Testing
Undergoing JAM3 gene testing provides numerous advantages for patients and their families:
- Accurate Diagnosis: Confirms or rules out JAM3-related disorders with high precision
- Treatment Guidance: Informs appropriate medical management and intervention strategies
- Prognostic Information: Helps understand disease progression and potential outcomes
- Family Planning: Provides crucial information for reproductive decisions
- Early Intervention: Enables timely implementation of supportive therapies
- Genetic Counseling: Supports informed decision-making for affected families
- Research Contribution: Advances understanding of rare neurological conditions
Understanding Your Test Results
Our comprehensive genetic counseling services help you interpret your JAM3 gene test results:
- Positive Result: Indicates the presence of pathogenic mutations in the JAM3 gene, confirming the diagnosis and providing information about inheritance patterns
- Negative Result: Suggests that JAM3 gene mutations are not responsible for the clinical symptoms, guiding physicians toward alternative diagnostic pathways
- Variant of Uncertain Significance: Identifies genetic changes whose clinical significance requires further investigation and possibly family studies
- Carrier Status: Determines if individuals carry one copy of a mutated gene, important for family planning decisions
All results are accompanied by detailed explanations and recommendations from our certified genetic counselors to ensure complete understanding and appropriate next steps.
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
| Turnaround Time | 3-4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
Nationwide Accessibility and Convenience
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Jacksonville, Fort Worth, Columbus, Charlotte, San Francisco, Indianapolis, Seattle, Denver, Washington DC, Boston, El Paso, Nashville, Detroit, Oklahoma City, Portland, Las Vegas, Memphis, Louisville, Baltimore, and Milwaukee. Our network of certified collection centers ensures that quality genetic testing is accessible to everyone, regardless of location.
Take the Next Step Toward Genetic Clarity
Don’t let uncertainty about neurological symptoms delay your path to accurate diagnosis and appropriate care. Our JAM3 Gene NGS Genetic DNA Test provides the definitive answers you need to make informed healthcare decisions. With our special discounted price of $500 USD and comprehensive genetic counseling support, you can access world-class genetic testing without financial burden.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your appointment or book your test online. Our genetic specialists are ready to guide you through the testing process and help you understand your results with compassion and expertise.
Remember, early genetic diagnosis can significantly impact treatment outcomes and quality of life for individuals affected by JAM3-related disorders. Take control of your genetic health journey with confidence and professional support from America’s leading genetics diagnostic provider.
