ITGB2 Gene Leukocyte Adhesion Deficiency NGS Genetic DNA Test
Comprehensive Genetic Analysis for Immune System Disorders
The ITGB2 Gene Leukocyte Adhesion Deficiency NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for rare immune system disorders. This advanced next-generation sequencing (NGS) test specifically targets the ITGB2 gene, which encodes the CD18 protein essential for proper white blood cell function. Leukocyte Adhesion Deficiency type 1 (LAD-1) is a serious primary immunodeficiency disorder that can lead to life-threatening infections if left undiagnosed.
What This Test Measures and Detects
Our comprehensive NGS genetic test analyzes the complete coding region of the ITGB2 gene to identify:
- Point mutations, insertions, and deletions in the ITGB2 gene
- Genetic variations affecting CD18 protein expression
- Mutations responsible for impaired leukocyte adhesion and migration
- Inheritance patterns for genetic counseling purposes
- Specific genetic markers associated with disease severity
Who Should Consider This Test
This genetic test is recommended for individuals experiencing:
- Recurrent bacterial infections without clear cause
- Delayed separation of the umbilical cord beyond 3 weeks
- Poor wound healing and impaired pus formation
- Severe gingivitis and periodontal disease
- Family history of primary immunodeficiency disorders
- Unexplained neutrophilia with recurrent infections
- Suspected immune system dysfunction in infants and children
Key Benefits of Genetic Testing
- Early Diagnosis: Enables prompt intervention before serious complications develop
- Personalized Treatment: Guides targeted therapeutic approaches
- Family Planning: Provides crucial information for genetic counseling
- Improved Outcomes: Early detection leads to better management and quality of life
- Definitive Answers: Eliminates diagnostic uncertainty for complex cases
Understanding Your Test Results
Your genetic test results will be carefully interpreted by our expert geneticists and presented in a comprehensive report:
- Positive Result: Indicates the presence of pathogenic mutations in the ITGB2 gene, confirming LAD-1 diagnosis
- Negative Result: No disease-causing mutations detected, though clinical correlation is essential
- Variant of Uncertain Significance: Genetic changes with unclear clinical impact requiring further evaluation
- Carrier Status: Identification of individuals carrying one copy of mutated gene
Test Pricing Information
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Nationwide Testing Availability
We have conveniently located testing centers across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art facilities ensure accurate sample collection and processing.
Take Control of Your Health Today
Don’t let uncertainty about immune system disorders affect your quality of life. Our ITGB2 Gene Leukocyte Adhesion Deficiency NGS Genetic DNA Test provides the definitive answers you need for proper diagnosis and treatment planning. With results available in 3-4 weeks and comprehensive genetic counseling support, you can make informed decisions about your health.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic test consultation and take the first step toward understanding your genetic health.
