ITGA3 Gene Interstitial Lung Disease, Nephrotic Syndrome and Epidermolysis Bullosa Congenital NGS Genetic DNA Test
Comprehensive Genetic Diagnosis for Complex Disorders
The ITGA3 Gene NGS Genetic DNA Test represents a breakthrough in molecular diagnostics, offering precise identification of mutations in the ITGA3 gene that are responsible for three distinct but interconnected medical conditions. This advanced genetic screening utilizes next-generation sequencing technology to provide healthcare providers with critical information for accurate diagnosis and targeted treatment strategies.
What Does the ITGA3 Gene Test Measure?
This sophisticated genetic analysis specifically targets the ITGA3 gene, which encodes the alpha-3 subunit of integrin proteins. Integrins play a crucial role in cell adhesion, migration, and signaling processes throughout the body. The test detects:
- Pathogenic variants and mutations in the ITGA3 gene
- Single nucleotide polymorphisms (SNPs) associated with disease risk
- Copy number variations affecting gene function
- Structural variants impacting protein expression
Clinical Significance of ITGA3 Mutations
Mutations in the ITGA3 gene disrupt normal integrin function, leading to impaired cellular adhesion in various tissues. This genetic defect manifests as three primary conditions:
- Interstitial Lung Disease: Progressive scarring and inflammation of lung tissue
- Nephrotic Syndrome: Kidney damage causing protein leakage and fluid retention
- Epidermolysis Bullosa Congenital: Severe skin fragility and blistering
Who Should Consider This Genetic Test?
This comprehensive genetic screening is recommended for individuals presenting with:
Respiratory Symptoms
- Progressive shortness of breath and chronic cough
- Persistent lung inflammation unresponsive to standard treatments
- Unexplained pulmonary fibrosis or scarring
- Family history of early-onset interstitial lung disease
Renal Manifestations
- Proteinuria (excess protein in urine)
- Edema and fluid retention
- Recurrent kidney dysfunction
- Family history of nephrotic syndrome
Dermatological Concerns
- Severe skin blistering with minimal trauma
- Congenital skin fragility
- Nail dystrophy and hair abnormalities
- Family history of epidermolysis bullosa
Significant Benefits of ITGA3 Genetic Testing
Undergoing this advanced genetic analysis provides numerous advantages for patients and healthcare providers:
Accurate Diagnosis
Provides definitive genetic confirmation of suspected conditions, eliminating diagnostic uncertainty and enabling targeted treatment approaches.
Personalized Treatment Planning
Genetic results guide the development of customized therapeutic strategies based on specific mutation types and their functional consequences.
Family Risk Assessment
Identifies at-risk family members, enabling early intervention and preventive measures for those carrying the same genetic variants.
Reproductive Counseling
Provides essential information for family planning decisions and prenatal testing options for affected individuals.
Understanding Your Test Results
Our comprehensive genetic counseling services help you interpret your results effectively:
Positive Result Interpretation
A positive result indicates the presence of pathogenic mutations in the ITGA3 gene. This confirmation enables:
- Implementation of targeted treatment protocols
- Specialized monitoring for associated complications
- Family member screening recommendations
- Access to specialized care and support resources
Negative Result Significance
A negative result suggests that ITGA3 gene mutations are not responsible for the clinical presentation. This information helps:
- Direct diagnostic evaluation toward alternative genetic causes
- Reduce unnecessary treatments and interventions
- Provide reassurance for family planning decisions
Variant of Uncertain Significance
Some genetic changes may have unknown clinical implications. In such cases, we provide:
- Detailed explanation of the variant’s characteristics
- Recommendations for additional family studies
- Guidance on clinical management while awaiting further research
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Test Specifications
- Turnaround Time: 3 to 4 Weeks
- Sample Type: Blood, Extracted DNA, or One Drop Blood on FTA Card
- Testing Method: Next-Generation Sequencing (NGS) Technology
- Specialty: Dermatology, Genetics, Immunology
Pre-Test Requirements
To ensure optimal testing outcomes, we recommend:
- Comprehensive clinical history documentation
- Genetic counseling session prior to testing
- Development of detailed family pedigree chart
- Discussion of testing implications and potential outcomes
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our extensive network ensures accessible genetic testing services regardless of your location.
Take Control of Your Genetic Health Today
Don’t let uncertainty about your genetic health prevent you from getting the answers you need. Our ITGA3 Gene NGS Genetic DNA Test provides the clarity required for informed medical decisions and personalized care planning. With our discounted price of $500 and comprehensive genetic counseling support, you can access world-class diagnostic services without financial burden.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic testing appointment or to speak with our genetic counseling team. Take the first step toward definitive diagnosis and targeted treatment for interstitial lung disease, nephrotic syndrome, and epidermolysis bullosa congenital.
