Immunophenotyping by Flow Cytometry Lymphoma Diagnostic Panel Test
Comprehensive Introduction to Lymphoma Immunophenotyping
Immunophenotyping by Flow Cytometry represents a cornerstone in modern lymphoma diagnosis and management. This advanced diagnostic technique utilizes sophisticated flow cytometry technology to analyze the unique protein markers expressed on the surface of lymphocytes, providing crucial information for accurate lymphoma classification and treatment planning. The test’s importance cannot be overstated, as it enables healthcare providers to distinguish between various lymphoma subtypes, each requiring specific therapeutic approaches.
Flow cytometry immunophenotyping has revolutionized lymphoma diagnosis by offering rapid, precise characterization of malignant cells. This technology allows for the simultaneous analysis of multiple cell surface markers, providing a comprehensive profile of the abnormal lymphocyte population. The ability to quickly identify specific lymphoma subtypes directly impacts treatment decisions, prognosis assessment, and patient outcomes.
What the Test Measures and Detects
The Immunophenotyping by Flow Cytometry Lymphoma Diagnostic Panel measures and analyzes specific cell surface markers that help identify and classify lymphoma cells. Key measurements include:
- B-cell Markers: CD19, CD20, CD22, CD79a for B-cell lymphomas
- T-cell Markers: CD2, CD3, CD4, CD5, CD7, CD8 for T-cell lymphomas
- Activation Markers: CD25, CD30, CD38 for activated lymphocyte identification
- Maturation Markers: CD10, CD34 for differentiation assessment
- Clonality Assessment: Light chain restriction analysis for B-cell clonality
The test detects abnormal immunophenotypic patterns that distinguish malignant lymphoma cells from normal lymphocytes, identifies specific lymphoma subtypes (such as follicular lymphoma, diffuse large B-cell lymphoma, or mantle cell lymphoma), and helps determine the cell of origin for proper classification.
Who Should Consider This Test
This diagnostic panel is recommended for individuals presenting with symptoms or clinical findings suggestive of lymphoma, including:
- Patients with unexplained lymph node enlargement that persists for more than 2-3 weeks
- Individuals experiencing unexplained fever, night sweats, or significant weight loss
- Patients with abnormal blood counts suggesting bone marrow involvement
- Individuals with suspicious imaging findings (CT, PET scans) indicating possible lymphoma
- Patients with established lymphoma requiring subtype confirmation or treatment monitoring
- Individuals with recurrent infections or autoimmune phenomena associated with lymphoproliferative disorders
Clinical Indications Include:
- Initial diagnosis of suspected lymphoma
- Classification of lymphoma subtype for treatment planning
- Monitoring treatment response and detecting minimal residual disease
- Evaluating disease progression or transformation
- Distinguishing between reactive and malignant lymphoproliferations
Benefits of Taking the Test
The Immunophenotyping by Flow Cytometry Lymphoma Diagnostic Panel offers numerous clinical advantages:
- Accurate Diagnosis: Provides precise identification of lymphoma subtypes, enabling targeted treatment approaches
- Rapid Results: Same-day reporting when samples are received by 9 am facilitates timely clinical decisions
- Comprehensive Analysis: Multiple marker analysis ensures thorough characterization of abnormal cell populations
- Treatment Guidance: Results directly influence chemotherapy selection and intensity decisions
- Prognostic Information: Certain immunophenotypic patterns provide valuable prognostic indicators
- Minimal Sample Requirement: Requires only small sample volumes, reducing patient discomfort
- Cost-Effective: Comprehensive panel at $550 USD provides exceptional diagnostic value
Understanding Your Test Results
Interpreting immunophenotyping results requires specialized expertise, but general guidance includes:
Normal Findings:
- Polyclonal B-cell population with normal light chain distribution
- Normal T-cell subset distribution and maturation patterns
- Absence of abnormal antigen expression patterns
Abnormal Findings May Include:
- Monoclonal B-cell population indicating B-cell lymphoma
- Aberrant antigen expression patterns specific to lymphoma subtypes
- Abnormal T-cell immunophenotypes suggesting T-cell lymphoma
- Increased blast populations in aggressive lymphomas
Your healthcare provider will discuss the specific findings in the context of your clinical presentation, imaging results, and other laboratory tests to formulate an accurate diagnosis and treatment plan.
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $550 |
| Regular Price | $750 |
Sample Requirements and Turnaround Time
- Blood: 3 mL (2 mL minimum) whole blood from 1 Lavender Top (EDTA) tube
- Bone Marrow: 3 mL (1.5 mL minimum) in 1 Green Top (Sodium Heparin) tube
- Body Fluids: 50 mL (10 mL minimum) fluids in sterile screw-capped container
- Lymph Node Aspirate: 1 mL (0.5 mL minimum) in normal saline
- Shipping: Ship at 18-22°C. DO NOT REFRIGERATE OR FREEZE
- Turnaround: Sample daily by 9 am; Report same day
- Mandatory: Clinical history is required for accurate interpretation
Nationwide Availability
We have diagnostic centers across all major cities in the United States, including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Jacksonville, Fort Worth, Columbus, Charlotte, San Francisco, Indianapolis, Seattle, Denver, Washington DC, Boston, El Paso, Nashville, Detroit, Oklahoma City, Portland, Las Vegas, Memphis, Louisville, Baltimore, and Milwaukee. Our extensive network ensures convenient access to this advanced diagnostic testing regardless of your location.
Take Action for Your Health
Early and accurate diagnosis is crucial for successful lymphoma management. The Immunophenotyping by Flow Cytometry Lymphoma Diagnostic Panel provides the comprehensive information needed for precise diagnosis and effective treatment planning. Don’t delay in obtaining the critical diagnostic information that could significantly impact your treatment journey.
Book your Immunophenotyping by Flow Cytometry Lymphoma Diagnostic Panel Test today by calling our dedicated healthcare line at +1(267) 388-9828. Our experienced staff will guide you through the scheduling process and answer any questions you may have about the test procedure, preparation, or results interpretation.
Take the first step toward accurate diagnosis and personalized lymphoma management. Contact us now to schedule your comprehensive immunophenotyping evaluation and benefit from same-day results and expert interpretation by our specialized hematopathology team.
