Immunophenotyping by Flow Cytometry CD23 Test
Comprehensive Introduction to CD23 Immunophenotyping
Immunophenotyping by Flow Cytometry CD23 Test represents a cutting-edge diagnostic approach in modern hematology and oncology. This sophisticated laboratory technique utilizes advanced flow cytometry technology to detect and quantify the presence of CD23 surface markers on immune cells, providing invaluable insights into various hematologic malignancies. The CD23 antigen, also known as Fc epsilon RII, serves as a crucial differentiation marker primarily expressed on mature B-cells and plays a significant role in immune regulation and B-cell development.
The importance of CD23 immunophenotyping cannot be overstated in contemporary cancer diagnostics. This test enables healthcare providers to accurately characterize abnormal cell populations, distinguish between different types of lymphoproliferative disorders, and establish precise diagnoses that directly influence treatment decisions. By identifying specific cell surface markers, physicians can develop targeted therapeutic strategies and monitor treatment response with unprecedented precision.
What the CD23 Test Measures and Detects
The Immunophenotyping by Flow Cytometry CD23 Test specifically measures the expression of CD23 antigens on the surface of white blood cells. This comprehensive analysis provides critical information about:
- Presence and density of CD23 markers on B-lymphocytes
- Identification of abnormal cell populations in blood and bone marrow
- Characterization of B-cell maturation and differentiation patterns
- Detection of malignant transformations in lymphoid cells
- Quantification of specific cell subsets for diagnostic classification
This advanced diagnostic tool employs multi-parameter flow cytometry, allowing simultaneous analysis of multiple cell surface markers to create comprehensive immunophenotypic profiles. The technology utilizes laser-based detection systems and fluorescent-labeled antibodies to identify and quantify specific cell populations with exceptional accuracy and sensitivity.
Who Should Consider CD23 Immunophenotyping Testing
This specialized test is particularly recommended for individuals presenting with specific clinical indications and symptoms suggestive of hematologic disorders:
Clinical Indications:
- Patients with unexplained lymphocytosis or abnormal lymphocyte counts
- Individuals presenting with persistent fatigue, unexplained weight loss, or night sweats
- Patients with enlarged lymph nodes, spleen, or liver without clear cause
- Those with recurrent infections or abnormal bleeding tendencies
- Individuals with family history of hematologic malignancies
Specific Patient Groups:
- Suspected cases of chronic lymphocytic leukemia (CLL)
- Patients being evaluated for B-cell lymphoproliferative disorders
- Individuals requiring differential diagnosis of lymphoid malignancies
- Patients undergoing monitoring for disease progression or treatment response
- Those with atypical blood cell morphology on peripheral smear
Significant Benefits of CD23 Immunophenotyping
Undergoing CD23 immunophenotyping provides numerous advantages for both patients and healthcare providers:
Diagnostic Precision
The test offers unparalleled accuracy in identifying specific cell markers, enabling precise diagnosis of hematologic malignancies. This level of diagnostic certainty helps avoid misdiagnosis and ensures appropriate treatment planning from the outset.
Treatment Guidance
By characterizing the immunophenotypic profile of malignant cells, the test provides essential information for selecting targeted therapies and monitoring treatment efficacy. This personalized approach maximizes therapeutic benefits while minimizing unnecessary side effects.
Prognostic Value
CD23 expression patterns provide valuable prognostic information, helping physicians predict disease course and tailor long-term management strategies accordingly.
Rapid Results
With same-day reporting available when samples are received by 9 AM, patients and physicians receive critical diagnostic information quickly, facilitating timely treatment decisions.
Understanding Your CD23 Test Results
Interpreting CD23 immunophenotyping results requires specialized expertise, but understanding the general principles can help patients better comprehend their diagnosis:
Normal Findings
Normal CD23 expression typically shows appropriate distribution on mature B-cells with expected intensity patterns. The absence of abnormal cell populations and normal distribution of lymphocyte subsets indicates healthy immune system function.
Abnormal Patterns
Elevated CD23 expression, particularly when combined with other marker abnormalities, may indicate chronic lymphocytic leukemia or other B-cell malignancies. The specific pattern of marker expression helps distinguish between different types of lymphoproliferative disorders.
Clinical Correlation
Results are always interpreted in the context of clinical presentation, other laboratory findings, and additional diagnostic tests. Your hematologist or oncologist will integrate all available information to provide comprehensive diagnostic assessment and treatment recommendations.
Test Pricing and Scheduling Information
| Test Description | Price (USD) |
|---|---|
| Immunophenotyping by Flow Cytometry CD23 Test – Discount Price | $88 |
| Immunophenotyping by Flow Cytometry CD23 Test – Regular Price | $112 |
Sample Requirements and Processing
For accurate testing, please provide:
- 3 mL (2 mL minimum) whole blood in 1 Lavender Top (EDTA) tube AND
- 3 mL (2 mL minimum) whole blood in 1 Green Top (Sodium Heparin) tube OR
- 2 mL (1 mL minimum) Bone marrow in 1 Green Top (Sodium heparin) tube
Important Instructions: Ship samples immediately at 18-22°C. DO NOT REFRIGERATE OR FREEZE. Always specify collection time, date, and complete clinical details on the test request form.
Turnaround Time
Samples received daily by 9:00 AM receive same-day reporting, ensuring rapid diagnostic information for timely clinical decision-making.
Nationwide Testing Availability
GGC DNA maintains comprehensive testing facilities across the United States, with specialized flow cytometry laboratories in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network of certified laboratories ensures consistent, high-quality testing standards nationwide.
Take Action for Your Health Today
Don’t wait to get the answers you need for proper diagnosis and treatment. Our team of experienced hematologists and oncology specialists is ready to provide comprehensive evaluation and personalized care. With advanced flow cytometry technology and same-day results, we deliver the diagnostic precision you deserve.
Call us now at +1(267) 388-9828 to schedule your CD23 immunophenotyping test or to speak with our medical specialists about your diagnostic needs. Early detection and accurate diagnosis are crucial for successful treatment outcomes – take the first step toward better health today.
