CD10 CALLA Immunophenotyping by Flow Cytometry Test
Comprehensive Introduction to CD10 CALLA Testing
Immunophenotyping by Flow Cytometry for CD10 CALLA represents a cutting-edge diagnostic approach in modern hematology and oncology. This sophisticated laboratory technique enables precise identification and characterization of blood cells based on their surface protein expression patterns. The CD10 antigen, also known as Common Acute Lymphoblastic Leukemia Antigen (CALLA), serves as a crucial marker in distinguishing various hematological malignancies, particularly acute lymphoblastic leukemia (ALL) and certain types of lymphoma.
The importance of CD10 CALLA immunophenotyping cannot be overstated in contemporary cancer diagnostics. By providing detailed information about cell lineage and differentiation stages, this test plays a vital role in accurate disease classification, prognosis assessment, and treatment strategy development. The ability to detect specific antigen patterns helps clinicians make informed decisions about targeted therapies and monitor treatment response effectively.
What the CD10 CALLA Test Measures and Detects
The CD10 CALLA Immunophenotyping test specifically measures the presence and intensity of CD10 antigen expression on the surface of white blood cells. This comprehensive analysis includes:
- Detection of CD10 antigen expression patterns
- Identification of abnormal cell populations
- Characterization of leukemia and lymphoma cell types
- Assessment of cell maturity and differentiation stages
- Evaluation of minimal residual disease after treatment
Flow cytometry technology enables simultaneous analysis of multiple cell surface markers, providing a comprehensive immunophenotypic profile that helps distinguish between different subtypes of hematological malignancies. The CD10 marker is particularly significant in B-cell lineage identification and is commonly expressed in precursor B-cell acute lymphoblastic leukemia and certain mature B-cell lymphomas.
Who Should Consider CD10 CALLA Testing
This specialized test is recommended for individuals presenting with specific clinical indications and symptoms that may suggest hematological disorders:
Clinical Indications:
- Unexplained fatigue and weakness persisting for weeks
- Persistent fever without apparent infection
- Night sweats and unexplained weight loss
- Enlarged lymph nodes or spleen
- Abnormal complete blood count results
- Unexplained bruising or bleeding tendencies
- Bone pain or joint discomfort
Patient Groups:
- Patients with suspected leukemia or lymphoma
- Individuals undergoing cancer diagnosis and classification
- Patients requiring treatment response monitoring
- Those with recurrent or persistent blood abnormalities
- Individuals with family history of hematological cancers
Significant Benefits of CD10 CALLA Immunophenotyping
Choosing the CD10 CALLA Immunophenotyping test provides numerous advantages for patients and healthcare providers:
- Accurate Diagnosis: Enables precise classification of hematological malignancies
- Treatment Guidance: Helps determine appropriate targeted therapies
- Prognostic Information: Provides insights into disease severity and expected outcomes
- Rapid Results: Same-day reporting for timely clinical decisions
- Minimal Residual Disease Detection: Monitors treatment effectiveness
- Comprehensive Analysis: Multiple parameter assessment for thorough evaluation
- Cost-Effective: Affordable testing with significant diagnostic value
Understanding Your CD10 CALLA Test Results
Interpreting CD10 CALLA immunophenotyping results requires professional medical expertise, but general guidance includes:
Positive CD10 Expression:
- May indicate presence of precursor B-cell acute lymphoblastic leukemia
- Could suggest certain types of Burkitt lymphoma
- May be present in some cases of follicular lymphoma
- Requires correlation with clinical presentation and other laboratory findings
Negative CD10 Expression:
- Does not rule out hematological malignancies
- May indicate different subtypes of leukemia or lymphoma
- Could suggest T-cell lineage disorders
- Requires comprehensive evaluation with additional markers
Your healthcare provider will interpret results in the context of your complete clinical picture, including symptoms, physical examination findings, and other diagnostic tests. Always discuss your results with your oncologist or hematologist for proper understanding and treatment planning.
Test Pricing and Availability
| Test Description | Price (USD) |
|---|---|
| CD10 CALLA Immunophenotyping by Flow Cytometry – Discount Price | $88 |
| CD10 CALLA Immunophenotyping by Flow Cytometry – Regular Price | $126 |
Sample Requirements and Processing
- Sample Type: 3 mL (2 mL minimum) whole blood in 1 Lavender Top (EDTA) tube AND 3 mL (2 mL minimum) whole blood in 1 Green Top (Sodium Heparin) tube OR 2 mL (1 mL minimum) Bone marrow in 1 Green Top (Sodium heparin) tube
- Shipping Instructions: Ship immediately at 18-22°C. DO NOT REFRIGERATE OR FREEZE
- Documentation: Specify time, date and clinical details on test request form
- Turnaround Time: Sample Daily by 9 am; Report Same day
Nationwide Availability and Booking Information
We have diagnostic centers conveniently located across the United States, serving patients in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our state-of-the-art facilities ensure consistent, high-quality testing standards nationwide.
Ready to schedule your CD10 CALLA Immunophenotyping test? Our dedicated team is available to assist you with appointment scheduling, answer your questions, and provide guidance throughout the testing process. Take the first step toward accurate diagnosis and effective treatment planning.
Call or WhatsApp us today at +1(267) 388-9828 to book your test or speak with our medical specialists. We’re committed to providing exceptional patient care and reliable diagnostic services to support your health journey.
