Immunohistochemistry TFE3 Test
Understanding the Immunohistochemistry TFE3 Test
The Immunohistochemistry TFE3 Test represents a cutting-edge diagnostic approach in cancer pathology, specifically designed to detect TFE3 protein expression in tumor tissues. This specialized test plays a pivotal role in identifying specific genetic alterations that drive certain types of cancers, particularly renal cell carcinomas and other malignancies associated with TFE3 gene fusions. As a sophisticated immunohistochemical analysis, it provides clinicians with essential information for accurate diagnosis and personalized treatment planning.
What Does the TFE3 Test Measure?
The Immunohistochemistry TFE3 Test specifically detects the presence and expression levels of TFE3 protein within tumor cells. This protein serves as a critical biomarker for:
- Identification of TFE3 gene fusions and translocations
- Detection of Xp11.2 translocation renal cell carcinomas
- Assessment of alveolar soft part sarcomas
- Evaluation of other TFE3-associated malignancies
Who Should Consider This Test?
This advanced diagnostic test is particularly recommended for patients presenting with:
- Suspected renal cell carcinoma with unusual histological features
- Younger patients with renal tumors
- Cases requiring differential diagnosis of translocation-associated cancers
- Patients with alveolar soft part sarcoma
- Individuals with tumors showing characteristic morphological features of TFE3-associated malignancies
Clinical Indications and Symptoms
Patients who may benefit from the Immunohistochemistry TFE3 Test typically present with:
- Renal masses or tumors detected through imaging studies
- Unusual cancer presentations in younger individuals
- Cases where standard diagnostic methods yield inconclusive results
- Tumors with specific histological patterns suggestive of translocation carcinomas
Benefits of Taking the Immunohistochemistry TFE3 Test
Choosing this specialized diagnostic approach offers numerous advantages:
- Accurate Diagnosis: Provides definitive identification of TFE3-associated cancers
- Treatment Guidance: Helps oncologists develop targeted treatment strategies
- Prognostic Information: Offers insights into disease progression and outcomes
- Personalized Medicine: Enables tailored therapeutic approaches based on specific genetic alterations
- Differential Diagnosis: Distinguishes between different types of renal cell carcinomas
Understanding Your Test Results
Your Immunohistochemistry TFE3 Test results will be interpreted by experienced pathologists and may indicate:
- Positive Result: Strong nuclear staining for TFE3 protein, suggesting the presence of TFE3 gene fusions
- Negative Result: Absence of significant TFE3 protein expression
- Interpretation: Results are correlated with clinical findings and other diagnostic tests
It’s essential to discuss your results with your healthcare provider, who will explain their clinical significance and implications for your treatment plan.
Test Pricing and Availability
| Test Name | Discount Price | Regular Price |
|---|---|---|
| Immunohistochemistry TFE3 Test | $88 USD | $112 USD |
Turnaround Time and Sample Requirements
We provide efficient testing services with the following turnaround times:
- Block Samples: 5 days
- Tissue Biopsy: 5 days
- Tissue Large Complex: 7 days
- Sample Collection: Daily by 6 PM
Sample Requirements
For accurate testing, please provide:
- Tumor tissue in 10% formal-saline OR formalin-fixed paraffin-embedded block
- Ship samples at room temperature
- Include copy of histopathology report
- Provide biopsy site information and clinical history
Nationwide Availability
We have diagnostic centers conveniently located across the United States, serving patients in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network ensures accessible, high-quality diagnostic services wherever you are.
Book Your Test Today
Take the first step toward accurate diagnosis and personalized treatment. Our experienced team is ready to assist you with scheduling and any questions you may have about the Immunohistochemistry TFE3 Test.
Call or WhatsApp us today: +1(267) 388-9828
Our dedicated healthcare professionals will guide you through the testing process, answer your questions, and ensure you receive the comprehensive care you deserve. Don’t wait – secure your accurate diagnosis and peace of mind with our specialized Immunohistochemistry TFE3 testing services.

