Immunohistochemistry Serum Associated Amyloid SAA Test
Comprehensive Introduction to SAA Amyloid Detection
The Immunohistochemistry Serum Associated Amyloid SAA Test represents a cutting-edge diagnostic approach for identifying and characterizing AA amyloidosis, a serious medical condition characterized by the abnormal accumulation of serum amyloid A protein in various tissues and organs. This advanced immunohistochemistry-based analysis provides clinicians with precise information about amyloid deposition patterns, enabling accurate diagnosis and informed treatment decisions.
Amyloidosis represents a group of diseases where abnormal proteins build up in tissues, potentially leading to organ dysfunction and failure. The SAA test specifically targets serum amyloid A protein, which accumulates in response to chronic inflammatory conditions. Early detection through this specialized testing method can significantly impact patient outcomes by facilitating timely intervention and appropriate management strategies.
What the Test Measures and Detects
The Immunohistochemistry Serum Associated Amyloid SAA Test employs sophisticated antibody-based techniques to identify and localize serum amyloid A protein deposits within tissue samples. This specialized analysis provides critical information about:
- Presence and distribution of AA amyloid deposits in biopsy specimens
- Extent of tissue involvement and organ damage
- Specific amyloid protein typing for accurate classification
- Patterns of amyloid deposition that inform prognosis
- Response to treatment in follow-up evaluations
This test utilizes formalin-fixed paraffin-embedded tissue blocks or fresh tissue samples preserved in 10% formal-saline, allowing for precise localization of amyloid deposits through advanced immunohistochemical staining methods.
Who Should Consider This Test
This specialized diagnostic test is recommended for individuals experiencing symptoms or clinical presentations suggestive of amyloidosis, including:
Clinical Indications and Symptoms
- Unexplained organ dysfunction, particularly kidney or liver abnormalities
- Chronic inflammatory conditions such as rheumatoid arthritis, inflammatory bowel disease, or chronic infections
- Proteinuria or nephrotic syndrome without clear cause
- Cardiac symptoms including heart failure with preserved ejection fraction
- Gastrointestinal disturbances, malabsorption, or unexplained weight loss
- Peripheral neuropathy or autonomic nervous system dysfunction
- Skin changes, bruising, or macroglossia (enlarged tongue)
Risk Factors
- Patients with long-standing inflammatory diseases
- Individuals with family history of amyloidosis
- Patients with chronic infections or autoimmune disorders
- Those undergoing evaluation for unexplained multi-organ involvement
Benefits of Taking the Immunohistochemistry SAA Test
Choosing the Immunohistochemistry Serum Associated Amyloid SAA Test provides numerous advantages for both patients and healthcare providers:
- Accurate Diagnosis: Precise identification of AA amyloidosis type enables targeted treatment approaches
- Early Intervention: Detection before significant organ damage occurs improves treatment outcomes
- Treatment Guidance: Results inform appropriate therapeutic strategies for underlying inflammatory conditions
- Prognostic Information: Extent and pattern of amyloid deposition help predict disease course
- Monitoring Capability: Enables tracking of treatment response and disease progression
- Comprehensive Analysis: Provides detailed information beyond standard histological examination
Understanding Your Test Results
Interpreting Immunohistochemistry SAA Test results requires careful consideration by qualified medical professionals. Here’s general guidance on understanding your findings:
Positive Results
A positive result indicates the presence of serum amyloid A protein deposits in the examined tissue. This confirms AA amyloidosis diagnosis and typically requires:
- Comprehensive evaluation of underlying inflammatory conditions
- Assessment of organ involvement and functional impairment
- Development of targeted treatment plan addressing the source of inflammation
- Regular monitoring of disease progression and treatment response
Negative Results
A negative result suggests absence of AA amyloid deposits in the sampled tissue. However, this doesn’t completely rule out amyloidosis, as:
- Sampling may have missed affected areas
- Other types of amyloidosis may be present
- Further testing or different sampling sites may be necessary
Interpretation Considerations
- Results should be correlated with clinical presentation and other laboratory findings
- Quantitative assessment of amyloid burden may provide prognostic information
- Pattern of deposition can indicate disease severity and progression
- Follow-up testing may be recommended to monitor treatment response
Test Pricing and Scheduling Information
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $88 |
| Regular Price | $112 |
Turnaround Time
- Sample Acceptance: Daily by 6 PM
- Block Analysis: 5 days
- Tissue Biopsy: 5 days
- Tissue Large Complex: 7 days
Sample Requirements
Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block. Ship at room temperature. Provide a copy of the Histopathology report, Site of biopsy and Clinical history.
Nationwide Availability and Booking
We have diagnostic centers conveniently located across major cities throughout the United States, including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our extensive network ensures accessible testing services for patients nationwide.
Ready to take control of your health? Book your Immunohistochemistry Serum Associated Amyloid SAA Test today! Our experienced team is available to answer your questions and schedule your appointment. Call us now at +1(267) 388-9828 or visit your nearest GGC DNA diagnostic center to arrange your testing.
Take the first step toward accurate diagnosis and effective management of amyloid-related conditions. Our specialized immunohistochemistry testing provides the clarity you need for informed healthcare decisions.
