Immunohistochemistry SATB2 Test: Advanced Cancer Diagnosis
Understanding the SATB2 Immunohistochemistry Test
The Immunohistochemistry SATB2 Test represents a cutting-edge diagnostic approach in cancer pathology, specifically designed to detect the presence of SATB2 protein in tissue samples. SATB2 (Special AT-rich sequence-binding protein 2) serves as a highly specific biomarker for colorectal adenocarcinoma, making this test invaluable for accurate cancer classification and treatment planning.
This advanced immunohistochemical technique utilizes specialized antibodies that bind specifically to SATB2 proteins within tissue samples. When these antibodies attach to their target proteins, they create visible staining patterns that pathologists can analyze under a microscope. The presence or absence of SATB2 staining provides critical diagnostic information about the tissue’s origin and characteristics.
What the SATB2 Test Detects and Measures
The Immunohistochemistry SATB2 Test specifically measures:
- SATB2 protein expression levels in tissue samples
- Nuclear staining patterns indicating colorectal origin
- Differentiation between colorectal cancer and other gastrointestinal malignancies
- Identification of metastatic colorectal cancer in unknown primary sites
- Tumor classification accuracy for treatment decision-making
SATB2 has emerged as one of the most reliable markers for colorectal adenocarcinoma, with studies showing over 85% sensitivity and 95% specificity for colorectal origin. This high accuracy makes it particularly valuable when traditional diagnostic methods yield ambiguous results.
Who Should Consider the SATB2 Test?
Clinical Indications and Symptoms
This test is recommended for patients experiencing:
- Unexplained metastatic cancer with unknown primary origin
- Suspected colorectal cancer based on imaging or clinical presentation
- Need for differential diagnosis between colorectal and other gastrointestinal cancers
- Previous inconclusive biopsy results requiring additional characterization
- Planning for targeted therapy requiring precise tumor classification
Patients presenting with symptoms such as unexplained weight loss, changes in bowel habits, rectal bleeding, abdominal pain, or iron deficiency anemia may benefit from this test when colorectal cancer is suspected but not confirmed through standard methods.
Benefits of the SATB2 Immunohistochemistry Test
Choosing the SATB2 test provides numerous advantages for patients and healthcare providers:
- Accurate Diagnosis: High specificity for colorectal cancer reduces misdiagnosis risks
- Treatment Guidance: Results directly influence chemotherapy and targeted therapy selection
- Metastatic Identification: Helps identify the primary site in metastatic disease
- Prognostic Information: SATB2 expression patterns may provide insights into disease progression
- Cost-Effective: Prevents unnecessary treatments by ensuring accurate diagnosis
- Rapid Results: Turnaround time of 5-7 days enables timely treatment decisions
Understanding Your SATB2 Test Results
Interpretation Guidelines
Your SATB2 test results will typically fall into one of these categories:
- Positive Result: Strong nuclear staining indicates colorectal origin, supporting diagnosis of colorectal adenocarcinoma
- Negative Result: Absence of staining suggests non-colorectal origin, requiring further investigation
- Focal Positive: Patchy staining may indicate specific subtypes or mixed tumor types
- Weak Positive: Light staining may require correlation with other clinical findings
It’s important to understand that test interpretation requires correlation with clinical history, imaging findings, and other pathological features. Your oncologist will discuss the specific implications of your results and how they impact your treatment plan.
Test Pricing and Availability
| Test Name | Discount Price | Regular Price |
|---|---|---|
| Immunohistochemistry SATB2 Test | $88 USD | $126 USD |
Nationwide Availability and Convenient Testing
We have diagnostic centers conveniently located across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art facilities ensure consistent, high-quality testing standards regardless of location.
Sample Requirements and Processing
For accurate SATB2 testing, we require:
- Tumor tissue preserved in 10% formal-saline OR formalin-fixed paraffin-embedded block
- Shipment at room temperature to maintain sample integrity
- Complete clinical documentation including histopathology report
- Detailed biopsy site information and comprehensive clinical history
Turnaround Times:
Samples received daily by 6 pm
Block samples: 5 days
Tissue biopsy: 5 days
Tissue large complex: 7 days
Take Control of Your Cancer Diagnosis Today
Don’t let uncertainty about your cancer diagnosis delay your treatment. The SATB2 Immunohistochemistry Test provides the clarity needed for effective treatment planning. Our experienced team of pathologists and oncologists work together to ensure you receive accurate, timely results.
Ready to schedule your test? Contact us today at +1(267) 388-9828 or book your appointment online. Our dedicated team is available to answer your questions and guide you through the testing process.
Early and accurate diagnosis is crucial for successful cancer treatment. Trust General Genetics Corporation for reliable, advanced diagnostic testing that puts your health first.
