Immunohistochemistry Prostate Specific Antigen (PSA) Test
Comprehensive Prostate Cancer Detection Through Advanced Tissue Analysis
The Immunohistochemistry Prostate Specific Antigen (PSA) Test represents a cornerstone in modern prostate cancer diagnostics, utilizing sophisticated immunohistochemical techniques to detect PSA protein expression in tissue specimens. This specialized laboratory procedure provides critical information for confirming prostate cancer diagnosis, determining tumor origin, and guiding personalized treatment strategies.
What Does the Immunohistochemistry PSA Test Measure?
This advanced diagnostic test specifically detects the presence and distribution of Prostate Specific Antigen protein within tissue samples using targeted antibody staining. The test measures:
- PSA protein expression levels in prostate tissue
- Cellular localization and intensity of PSA staining
- Pattern of protein distribution within tumor cells
- Percentage of positive tumor cells
- Staining intensity correlation with tumor differentiation
Who Should Consider This Test?
The Immunohistochemistry PSA Test is recommended for patients experiencing:
- Elevated serum PSA levels requiring tissue confirmation
- Suspicious prostate biopsy findings needing definitive diagnosis
- Metastatic cancer of unknown primary origin
- Previous abnormal digital rectal exam results
- Family history of prostate cancer with concerning symptoms
- Monitoring treatment response in diagnosed prostate cancer
- Differentiating prostate cancer from benign conditions
Clinical Benefits of Immunohistochemistry PSA Testing
This specialized diagnostic approach offers numerous advantages for patient care:
- Precise Cancer Confirmation: Provides definitive evidence of prostate cancer presence in tissue samples
- Tumor Origin Identification: Helps determine if metastatic tumors originated from the prostate
- Treatment Guidance: Informs appropriate therapeutic decisions based on tumor characteristics
- Prognostic Information: Staining patterns may correlate with disease aggressiveness
- Minimized Misdiagnosis: Reduces false positive and false negative results
- Comprehensive Assessment: Evaluates tumor biology beyond standard histology
Understanding Your Test Results
Your Immunohistochemistry PSA Test results will include detailed information about PSA protein expression in your tissue sample:
- Positive Result: Indicates PSA protein detection, confirming prostate tissue origin
- Negative Result: Suggests absence of PSA expression, potentially ruling out prostate origin
- Staining Intensity: Ranges from weak to strong, potentially correlating with tumor differentiation
- Distribution Pattern: Describes how PSA is distributed within tumor cells
- Percentage of Positive Cells: Quantifies the proportion of tumor cells expressing PSA
Your healthcare provider will interpret these results in the context of your clinical history, physical examination findings, and other diagnostic tests to develop an appropriate management plan.
Test Pricing and Availability
| Test Description | Price (USD) |
|---|---|
| Immunohistochemistry Prostate Specific Antigen (PSA) Test – Discount Price | $76 |
| Immunohistochemistry Prostate Specific Antigen (PSA) Test – Regular Price | $112 |
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified laboratories ensures consistent, high-quality results regardless of your location.
Sample Requirements and Turnaround Time
For accurate testing, please provide:
- Tumor tissue preserved in 10% formal-saline solution
- Formalin-fixed paraffin-embedded tissue blocks
- Complete histopathology report copy
- Detailed biopsy site information
- Comprehensive clinical history
Turnaround Times:
- Standard tissue blocks: 5 days
- Tissue biopsy samples: 5 days
- Large complex tissue specimens: 7 days
Samples accepted daily until 6:00 PM for same-day processing.
Take Control of Your Prostate Health Today
Early and accurate diagnosis is crucial for successful prostate cancer management. Our Immunohistochemistry PSA Test provides the definitive information your healthcare team needs to make informed treatment decisions. Don’t wait – schedule your test now and take the first step toward comprehensive prostate health assessment.
Call or WhatsApp us today at +1(267) 388-9828 to book your Immunohistochemistry Prostate Specific Antigen Test and receive professional guidance throughout the testing process.

