Immunohistochemistry Polyoma BK Virus SV40 Test
Comprehensive Introduction to BK Virus Detection
The Immunohistochemistry Polyoma BK Virus SV40 Test represents a cutting-edge diagnostic approach for detecting BK virus infections in kidney tissues. This specialized immunohistochemical analysis plays a vital role in identifying polyomavirus-associated nephropathy, particularly in immunocompromised patients and kidney transplant recipients. The test’s importance lies in its ability to provide definitive evidence of active viral replication within renal tissues, enabling healthcare providers to make informed decisions about treatment strategies and immunosuppression management.
What This Test Measures and Detects
This sophisticated diagnostic test specifically targets the detection of SV40 large T antigen, a protein marker expressed during active BK virus replication. The immunohistochemistry methodology utilizes highly specific antibodies that bind to viral antigens present in infected kidney cells, creating visible staining patterns under microscopic examination.
Key Detection Capabilities:
- Identification of BK virus-infected renal tubular epithelial cells
- Detection of SV40 large T antigen expression patterns
- Assessment of viral load and distribution within kidney tissue
- Differentiation between active infection and latent viral presence
- Correlation with histopathological findings for comprehensive diagnosis
Who Should Consider This Test
This test is particularly essential for specific patient populations experiencing symptoms or risk factors associated with BK virus infection.
Primary Candidates Include:
- Kidney transplant recipients showing elevated serum creatinine levels
- Patients with unexplained renal allograft dysfunction
- Immunocompromised individuals with suspected viral nephropathy
- Patients presenting with hematuria or proteinuria of unknown origin
- Individuals with positive BK virus PCR results requiring tissue confirmation
- Patients undergoing evaluation for graft rejection versus infection
Significant Benefits of Testing
Undergoing the Immunohistochemistry Polyoma BK Virus SV40 Test offers numerous advantages for patient care and treatment outcomes.
Key Benefits:
- Early detection of BK virus nephropathy before irreversible damage occurs
- Accurate differentiation between viral infection and transplant rejection
- Guidance for appropriate antiviral therapy initiation and monitoring
- Informed decisions regarding immunosuppression adjustment
- Prevention of allograft loss through timely intervention
- Comprehensive tissue-based diagnosis complementing serum testing
- Improved long-term kidney function preservation
Understanding Your Test Results
Interpreting the results of your Immunohistochemistry Polyoma BK Virus SV40 Test requires professional medical expertise, but understanding the general principles can help you better comprehend your diagnosis.
Result Interpretation Guidelines:
- Positive Result: Indicates active BK virus replication in kidney tissue, typically showing nuclear staining in tubular epithelial cells
- Negative Result: Suggests absence of detectable BK virus activity in the examined tissue sample
- Focal Positivity: May indicate early or limited infection requiring close monitoring
- Extensive Positivity: Often correlates with more advanced viral nephropathy
Your healthcare provider will correlate these findings with clinical symptoms, laboratory values, and other diagnostic tests to develop a comprehensive treatment plan.
Test Pricing Information
| Test Name | Discount Price | Regular Price |
|---|---|---|
| Immunohistochemistry Polyoma BK Virus SV40 Test | $88 USD | $146 USD |
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas. Our network includes specialized facilities in New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and numerous other cities. Each location maintains the same high standards of diagnostic excellence and patient care.
Take Action for Your Kidney Health
Don’t wait to address potential BK virus concerns. Early detection through our Immunohistochemistry Polyoma BK Virus SV40 Test can make a significant difference in treatment outcomes and kidney function preservation. Our experienced team is ready to assist you with comprehensive testing and clear result interpretation.
Book your test today by calling our dedicated healthcare line at +1(267) 388-9828 or schedule your appointment online. Take the first step toward accurate diagnosis and effective treatment management.
Test Specifications:
- Turnaround Time: Block: 5 days | Tissue Biopsy: 5 days | Tissue Large Complex: 7 days
- Sample Requirements: Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block
- Shipping Instructions: Ship at room temperature with required documentation
- Required Documentation: Histopathology report, biopsy site information, and clinical history
