Immunohistochemistry PLAP Test: Advanced Cancer Detection
Understanding the Immunohistochemistry PLAP Test
The Immunohistochemistry PLAP Test represents a cutting-edge diagnostic approach in cancer pathology, specifically designed to detect Placental Alkaline Phosphatase (PLAP) expression in tissue samples. This sophisticated laboratory technique utilizes specific antibodies to identify PLAP proteins, which serve as crucial biomarkers for various types of germ cell tumors and certain carcinomas. The test plays a vital role in modern oncology by providing pathologists and clinicians with precise information about tumor characteristics, enabling more accurate diagnoses and personalized treatment planning.
What Does the PLAP Test Measure?
The Immunohistochemistry PLAP Test specifically detects the presence and distribution of Placental Alkaline Phosphatase, an enzyme normally produced by the placenta during pregnancy. In diagnostic pathology, PLAP serves as an important tumor marker that helps identify:
- Germ cell tumors including seminomas and dysgerminomas
- Ovarian and testicular cancers of germ cell origin
- Certain types of epithelial ovarian tumors
- Metastatic cancers of unknown primary origin
- Tumors with placental-like alkaline phosphatase expression
Who Should Consider This Test?
The Immunohistochemistry PLAP Test is recommended for patients presenting with specific clinical scenarios and symptoms, including:
- Patients with suspected germ cell tumors based on imaging studies
- Individuals with testicular or ovarian masses requiring precise characterization
- Patients with metastatic cancer where the primary site is unknown
- Those with elevated serum tumor markers suggesting germ cell origin
- Cases requiring differential diagnosis between different tumor types
- Patients needing confirmation of tumor type before treatment initiation
Key Benefits of the PLAP Test
Choosing the Immunohistochemistry PLAP Test offers numerous advantages for accurate cancer diagnosis and management:
- Precise Tumor Identification: Helps distinguish germ cell tumors from other malignancies
- Treatment Guidance: Provides critical information for selecting appropriate chemotherapy regimens
- Prognostic Information: Aids in determining disease prognosis and expected outcomes
- Minimally Invasive: Utilizes existing tissue samples from biopsies or surgeries
- High Specificity: Offers reliable detection of PLAP-positive tumors
- Comprehensive Analysis: Integrates with other diagnostic markers for complete tumor profiling
Understanding Your Test Results
Interpreting Immunohistochemistry PLAP Test results requires professional medical expertise, but here’s general guidance:
- Positive Result: Indicates PLAP expression in tumor cells, typically associated with germ cell tumors
- Negative Result: Suggests absence of PLAP expression, helping rule out certain tumor types
- Focal Positivity: Partial staining may indicate mixed tumor types or specific subtypes
- Intensity Grading: The strength of staining can provide additional diagnostic information
Your healthcare provider will discuss the specific implications of your results in the context of your overall clinical picture and other diagnostic findings.
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $88 |
| Regular Price | $112 |
Nationwide Testing Availability
GGC DNA provides comprehensive Immunohistochemistry PLAP testing services across the United States. We have established branches in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our network ensures that patients nationwide have access to this advanced diagnostic technology.
Book Your Test Today
Take the first step toward accurate cancer diagnosis and personalized treatment planning. Our experienced team is ready to assist you with scheduling your Immunohistochemistry PLAP Test and answering any questions you may have about the procedure, preparation, or results interpretation.
Call or WhatsApp us today at +1(267) 388-9828 to book your test or speak with our genetic counseling specialists.
Sample Requirements and Processing
For optimal results, please provide:
- Tumor tissue preserved in 10% formal-saline solution
- Formalin-fixed paraffin-embedded tissue blocks
- Complete clinical history and biopsy site information
- Copy of the histopathology report
- All samples should be shipped at room temperature
Turnaround Time
- Samples accepted daily until 6:00 PM
- Standard tissue blocks: 5 days
- Tissue biopsy samples: 5 days
- Large complex tissue specimens: 7 days
