Immunohistochemistry PAX8 Test: Advanced Cancer Detection and Diagnosis
Understanding the Immunohistochemistry PAX8 Test
The Immunohistochemistry PAX8 Test represents a cutting-edge diagnostic approach in cancer pathology that utilizes specialized antibodies to detect the presence of PAX8 protein in tissue samples. PAX8 (Paired Box 8) is a transcription factor protein that plays a crucial role in the development and differentiation of specific organs, including the kidneys, thyroid gland, and Müllerian-derived tissues in the female reproductive system. This test has revolutionized cancer diagnosis by providing pathologists with precise molecular markers to identify the tissue origin of tumors, particularly in cases where the primary site is unknown or when differentiating between similar-looking cancers.
What the PAX8 Test Measures and Detects
The Immunohistochemistry PAX8 Test specifically measures the expression of PAX8 protein in tissue specimens through advanced staining techniques. This sophisticated diagnostic tool detects:
- Presence of PAX8 nuclear staining in tumor cells
- Tissue-specific protein expression patterns
- Cellular origin identification for metastatic cancers
- Differentiation between various carcinoma types
- Confirmation of Müllerian origin in gynecological cancers
- Renal cell carcinoma markers
- Thyroid carcinoma indicators
Who Should Consider the PAX8 Test
This specialized test is particularly important for patients presenting with:
- Suspected ovarian cancer or ovarian masses
- Undiagnosed pelvic tumors in women
- Metastatic cancer of unknown primary origin
- Suspected renal cell carcinoma
- Thyroid nodules or suspected thyroid cancer
- Complex gynecological malignancies
- Patients requiring differential diagnosis between similar cancer types
- Individuals with family history of related cancers
Key Benefits of the PAX8 Test
Choosing the Immunohistochemistry PAX8 Test provides numerous clinical advantages:
- Precise Diagnosis: Enables accurate identification of cancer type and origin
- Treatment Guidance: Helps oncologists develop targeted treatment plans
- Prognostic Information: Provides insights into disease progression and outcomes
- Minimized Misdiagnosis: Reduces the risk of incorrect cancer classification
- Personalized Medicine: Supports individualized treatment approaches
- Comprehensive Assessment: Complements other diagnostic methods for complete evaluation
Understanding Your Test Results
Your PAX8 test results will be interpreted by experienced pathologists and oncologists:
- Positive Result: Indicates presence of PAX8 protein, suggesting tumors of renal, thyroid, or Müllerian origin
- Negative Result: Suggests the tumor likely originates from other tissue types
- Pattern Analysis: The staining pattern and intensity provide additional diagnostic information
- Clinical Correlation: Results are interpreted in context with other clinical findings and tests
- Follow-up Recommendations: Your healthcare provider will discuss appropriate next steps based on results
Test Pricing and Availability
| Test Name | Discount Price | Regular Price |
|---|---|---|
| Immunohistochemistry PAX8 Test | $88 USD | $126 USD |
Nationwide Availability
We have diagnostic centers conveniently located across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our state-of-the-art facilities ensure consistent, high-quality testing standards nationwide.
Sample Requirements and Turnaround Time
Sample Type: Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block. Ship at room temperature.
Required Documentation: Provide a copy of the Histopathology report, Site of biopsy and Clinical history.
Turnaround Time:
- Sample Daily by 6 pm
- Report Block: 5 days
- Tissue Biopsy: 5 days
- Tissue large complex: 7 days
Take Control of Your Health Today
Don’t let uncertainty about your diagnosis delay your treatment. The Immunohistochemistry PAX8 Test provides the clarity you need for effective cancer management. Our team of specialized pathologists and oncologists are ready to help you get the answers you deserve.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your test or speak with our healthcare specialists. Take the first step toward accurate diagnosis and personalized treatment planning.
