Immunohistochemistry P40 Test: Advanced Cancer Detection and Diagnosis
Understanding the Immunohistochemistry P40 Test
The Immunohistochemistry P40 Test represents a cutting-edge diagnostic approach in cancer pathology that specifically targets the p40 protein, a crucial biomarker for squamous cell carcinoma identification. This sophisticated laboratory technique utilizes specialized antibodies to detect the presence of p40, which is a specific isoform of the p63 protein family. The test plays a vital role in modern oncology by providing pathologists with precise molecular information about tumor characteristics, enabling more accurate cancer classification and treatment planning.
What Does the P40 Test Measure and Detect?
The Immunohistochemistry P40 Test specifically identifies the presence of the p40 protein, which serves as a highly specific marker for squamous cell differentiation in various tissues. This test helps distinguish:
- Squamous cell carcinoma from other cancer types
- Primary lung squamous cell carcinoma from adenocarcinoma
- Head and neck squamous cell carcinomas
- Esophageal and cervical squamous cell carcinomas
- Other malignancies with squamous differentiation
Clinical Significance of P40 Detection
The p40 protein is a nuclear transcription factor that plays a critical role in epithelial development and differentiation. Its presence in tumor cells indicates squamous lineage, making it an invaluable tool for accurate cancer typing and subsequent treatment decisions.
Who Should Consider the Immunohistochemistry P40 Test?
This specialized diagnostic test is recommended for patients with:
- Suspected lung cancer where differentiation between squamous cell carcinoma and adenocarcinoma is needed
- Head and neck masses requiring precise cancer classification
- Biopsy samples with uncertain histological features
- Previous cancer diagnoses requiring confirmation of squamous cell origin
- Metastatic tumors where the primary site needs identification
Symptoms and Clinical Indications
Patients experiencing persistent cough, unexplained weight loss, difficulty swallowing, voice changes, or abnormal masses in the head, neck, or lung regions may benefit from this diagnostic evaluation when combined with appropriate clinical assessment.
Benefits of Taking the Immunohistochemistry P40 Test
- Precise Cancer Classification: Provides definitive identification of squamous cell carcinoma
- Treatment Guidance: Helps oncologists select appropriate targeted therapies
- Prognostic Information: Offers insights into cancer behavior and potential outcomes
- Minimized Misdiagnosis: Reduces the risk of incorrect cancer typing
- Comprehensive Analysis: Works alongside other diagnostic methods for complete evaluation
Understanding Your Test Results
Your Immunohistochemistry P40 Test results will be interpreted by board-certified pathologists and typically fall into these categories:
Positive Result
A positive result indicates the presence of p40 protein in the tested tissue sample, strongly suggesting squamous cell carcinoma. This finding helps guide treatment decisions, as squamous cell carcinomas may respond differently to certain therapies compared to other cancer types.
Negative Result
A negative result means p40 protein was not detected in the sample. This finding helps exclude squamous cell carcinoma and may point toward other cancer types that require different diagnostic approaches and treatment strategies.
Interpretation Context
It’s important to understand that test results are interpreted in the context of your complete clinical picture, including other laboratory findings, imaging studies, and physical examination results. Your healthcare provider will discuss what your specific results mean for your diagnosis and treatment plan.
Test Pricing and Availability
| Test Description | Price (USD) |
|---|---|
| Immunohistochemistry P40 Test | $88 USD (Discounted from $120) |
Turnaround Time
- Sample Submission: Daily by 6 PM
- Standard Tissue Block: 5 days
- Tissue Biopsy: 5 days
- Large Complex Tissue: 7 days
Sample Requirements and Preparation
For accurate testing, please provide:
- Tumor tissue preserved in 10% formal-saline OR formalin-fixed paraffin-embedded block
- Ship samples at room temperature with proper packaging
- Include a copy of the histopathology report
- Provide biopsy site information and complete clinical history
Nationwide Accessibility
GGC DNA has diagnostic centers conveniently located across the United States, serving patients in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our network ensures that advanced cancer diagnostics are accessible to patients nationwide.
Book Your Immunohistochemistry P40 Test Today
Take the next step in your diagnostic journey with confidence. Our team of experienced pathologists and laboratory professionals is ready to provide you with accurate, reliable results that can make a significant difference in your cancer care.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your test or speak with our genetic counseling team. We’re here to answer your questions and help you navigate your diagnostic needs with compassion and expertise.
Early and accurate cancer diagnosis can significantly impact treatment outcomes. Don’t delay – contact GGC DNA today to schedule your Immunohistochemistry P40 Test and take control of your health journey.
