Immunohistochemistry Isocitrate Dehydrogenase IDH1 Test
Understanding the IDH1 Test for Cancer Detection
The Immunohistochemistry Isocitrate Dehydrogenase IDH1 Test represents a cutting-edge diagnostic approach in modern oncology. This specialized test detects mutations in the IDH1 gene, which have emerged as critical biomarkers in various cancer types, particularly brain tumors and hematological malignancies. The identification of IDH1 mutations has revolutionized cancer classification and treatment strategies, providing clinicians with essential information for personalized medicine approaches.
What Does the IDH1 Test Measure?
This advanced diagnostic test specifically detects mutations in the isocitrate dehydrogenase 1 (IDH1) gene using immunohistochemistry techniques. The test identifies:
- Presence of mutant IDH1 protein in tumor tissue
- Specific R132H mutation patterns (most common IDH1 mutation)
- Abnormal metabolic enzyme activity in cancer cells
- Biomarker expression that distinguishes tumor subtypes
Who Should Consider This Test?
The Immunohistochemistry IDH1 Test is recommended for patients with:
- Newly diagnosed gliomas or brain tumors
- Suspected low-grade gliomas requiring accurate classification
- Patients with acute myeloid leukemia (AML)
- Individuals with cholangiocarcinoma or other solid tumors
- Patients requiring prognostic information for treatment planning
- Those being evaluated for targeted therapy eligibility
Clinical Indications and Symptoms
Patients experiencing neurological symptoms such as seizures, headaches, cognitive changes, or those with abnormal imaging findings suggestive of brain tumors should discuss this test with their healthcare provider. The test is particularly valuable for distinguishing between different glioma subtypes and guiding appropriate treatment strategies.
Benefits of the IDH1 Mutation Test
- Accurate Diagnosis: Provides precise classification of tumor types
- Treatment Guidance: Helps determine eligibility for targeted therapies
- Prognostic Information: IDH1 mutations often indicate better prognosis in gliomas
- Personalized Medicine: Enables tailored treatment approaches
- Cost-Effective Screening: Affordable mutation detection at only $88 USD
- Rapid Results: Turnaround time of 5-7 days for treatment planning
Understanding Your Test Results
Positive Result (IDH1 Mutation Detected)
A positive result indicates the presence of an IDH1 mutation in the tumor tissue. This finding typically suggests:
- Specific glioma subtypes (often lower grade)
- Better prognosis compared to IDH1 wild-type tumors
- Potential eligibility for targeted therapy options
- Distinct metabolic characteristics of the tumor
Negative Result (No IDH1 Mutation Detected)
A negative result means no IDH1 mutation was identified. This may indicate:
- Different tumor classification requiring alternative testing
- Possible higher-grade tumor characteristics
- Need for additional molecular testing
- Alternative treatment approaches may be necessary
Test Pricing and Availability
| Test Name | Discount Price | Regular Price |
|---|---|---|
| Immunohistochemistry Isocitrate Dehydrogenase IDH1 Test | $88 USD | $112 USD |
Turnaround Time and Sample Requirements
- Sample Collection: Daily by 6 PM
- Report Time: 5 days for blocks and tissue biopsy
- Complex Cases: 7 days for large or complex tissue samples
- Sample Type: Submit tumor tissue in 10% formal-saline OR formalin-fixed paraffin-embedded block
- Shipping: Room temperature
- Required Documentation: Histopathology report, biopsy site information, and clinical history
Nationwide Availability Across USA
We have diagnostic centers conveniently located in all major cities throughout the United States, including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network ensures accessible testing services for patients nationwide.
Book Your Test Today
Take the first step toward accurate cancer diagnosis and personalized treatment planning. Our experienced team of oncologists and pathologists are ready to provide you with comprehensive testing services and expert interpretation of your results.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your Immunohistochemistry IDH1 Test. Our dedicated healthcare professionals will guide you through the testing process and ensure you receive the highest quality care and accurate results.
Don’t wait – early detection and accurate classification can significantly impact your treatment outcomes and quality of life. Contact us now to book your appointment and take control of your health journey.
