Immunohistochemistry HMB45 Test: Advanced Melanoma Detection
Understanding the Immunohistochemistry HMB45 Test
The Immunohistochemistry HMB45 Test represents a cornerstone in modern cancer diagnostics, specifically designed to detect melanoma – one of the most aggressive forms of skin cancer. This sophisticated laboratory technique utilizes specialized antibodies that bind specifically to the HMB45 antigen, a glycoprotein found predominantly in melanoma cells and melanocytes. The test provides pathologists and oncologists with crucial diagnostic information that helps distinguish melanoma from other skin malignancies and benign lesions.
Immunohistochemistry (IHC) has revolutionized cancer diagnosis by enabling precise identification of specific cellular markers. The HMB45 test specifically targets the gp100 protein, which plays a critical role in melanin production and serves as a reliable marker for melanocytic differentiation. This advanced diagnostic approach allows for accurate classification of tumors and provides essential information for treatment planning and prognosis assessment.
What the HMB45 Test Detects and Measures
The Immunohistochemistry HMB45 Test specifically identifies the presence of HMB45 antigen in tissue samples, providing several key diagnostic insights:
- Melanoma Confirmation: Detects the presence of melanoma cells in suspicious tissue samples
- Tumor Differentiation: Helps distinguish melanoma from other skin cancers and benign lesions
- Metastatic Identification: Identifies melanoma cells in lymph nodes or distant organs
- Diagnostic Clarification: Provides definitive evidence in challenging diagnostic cases
- Treatment Guidance: Informs targeted therapy decisions based on specific melanoma markers
Who Should Consider the HMB45 Test?
This specialized diagnostic test is recommended for individuals in several clinical scenarios:
Primary Diagnostic Situations
- Patients with suspicious skin lesions showing atypical features
- Individuals with changing moles or new pigmented growths
- Cases where clinical examination suggests possible melanoma
- Patients with a personal or family history of melanoma
Secondary Diagnostic Applications
- Confirmation of melanoma diagnosis in ambiguous cases
- Evaluation of metastatic tumors of unknown origin
- Assessment of lymph node involvement in melanoma patients
- Monitoring treatment response in advanced melanoma cases
Key Benefits of the HMB45 Test
Choosing the Immunohistochemistry HMB45 Test provides numerous advantages for patients and healthcare providers:
- High Diagnostic Accuracy: Provides reliable confirmation of melanoma diagnosis with exceptional specificity
- Early Detection Capability: Enables identification of melanoma at earlier, more treatable stages
- Treatment Personalization: Guides targeted therapy selection based on specific tumor markers
- Prognostic Information: Helps assess disease progression and potential treatment outcomes
- Comprehensive Cancer Care: Integrates seamlessly with other diagnostic and treatment approaches
Understanding Your Test Results
Interpreting HMB45 test results requires professional medical expertise, but understanding the basic principles can help patients participate more actively in their care:
Positive Results
A positive HMB45 result indicates the presence of melanoma cells in the tested tissue sample. This finding typically confirms melanoma diagnosis and helps guide subsequent treatment decisions. Positive results may vary in intensity, providing additional information about tumor characteristics and aggressiveness.
Negative Results
A negative result suggests the absence of detectable HMB45 antigen in the sample. While this may indicate the lesion is not melanoma, it’s important to note that some melanoma subtypes may not express HMB45. Your healthcare provider will interpret negative results in the context of other clinical and pathological findings.
Clinical Correlation
All HMB45 test results should be interpreted by qualified pathologists and oncologists who consider the complete clinical picture, including physical examination findings, patient history, and other diagnostic test results.
Test Pricing and Availability
| Test Name | Discount Price | Regular Price |
|---|---|---|
| Immunohistochemistry HMB45 Test | $76 USD | $112 USD |
Nationwide Testing Network
We proudly offer the Immunohistochemistry HMB45 Test across our extensive network of testing facilities throughout the United States. Our state-of-the-art laboratories are strategically located in major metropolitan areas including:
- New York City and surrounding areas
- Los Angeles and Southern California
- Chicago and the Midwest region
- Houston and Texas metropolitan areas
- Phoenix and Arizona communities
- All other major US cities and regions
Our commitment to accessibility ensures that patients nationwide can benefit from this advanced diagnostic technology without the need for extensive travel or delays in care.
Take Control of Your Health Today
Early and accurate diagnosis is crucial for successful melanoma treatment. The Immunohistochemistry HMB45 Test provides the definitive information needed to make informed decisions about your health care. Don’t wait – take the first step toward clarity and peace of mind.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your test or speak with our knowledgeable healthcare coordinators. Our team is ready to answer your questions, explain the testing process, and help you take the next step in your healthcare journey.
With our discounted price of only $76 USD (regularly $112) and nationwide availability, there’s no reason to delay this important diagnostic step. Trust the experts at General Genetics Corporation for accurate, reliable, and timely melanoma testing services.
