Immunohistochemistry HBME1 Test: Advanced Cancer Biomarker Detection
Understanding the Immunohistochemistry HBME1 Test
The Immunohistochemistry HBME1 Test represents a cutting-edge diagnostic approach in cancer pathology, specifically designed to detect the Hector Battifora Mesothelial Epitope-1 (HBME1) antigen. This specialized immunohistochemical analysis plays a pivotal role in distinguishing mesothelioma from other malignancies and identifying various epithelial tumors with remarkable precision. As a monoclonal antibody-based test, HBME1 targets specific cellular markers that are expressed in mesothelial cells and certain cancer types, providing oncologists with critical diagnostic information that directly impacts treatment planning and patient outcomes.
What Does the HBME1 Test Measure and Detect?
The Immunohistochemistry HBME1 Test specifically identifies the presence and distribution of the HBME1 antigen within tissue samples. This biomarker is particularly valuable for:
- Detecting mesothelioma cells in pleural and peritoneal tissues
- Differentiating mesothelioma from adenocarcinoma and other malignancies
- Identifying thyroid carcinoma subtypes, especially papillary thyroid cancer
- Assessing epithelial differentiation in various tumor types
- Providing cellular localization patterns that aid in tumor classification
Who Should Consider the HBME1 Test?
This advanced diagnostic test is recommended for patients presenting with:
- Suspected mesothelioma based on clinical symptoms and imaging findings
- Undiagnosed pleural or peritoneal effusions of unknown origin
- Thyroid nodules or masses requiring precise histological characterization
- Previous asbestos exposure with concerning respiratory symptoms
- Complex cases where standard histopathology provides inconclusive results
- Patients requiring differential diagnosis between mesothelioma and lung adenocarcinoma
Clinical Indications and Symptoms
Patients experiencing persistent chest pain, unexplained weight loss, respiratory difficulties, pleural effusions, or abdominal swelling should discuss the HBME1 test with their oncologist. The test is particularly crucial when:
- Conventional biopsy results are ambiguous
- Multiple cancer types are in the differential diagnosis
- Treatment planning requires precise tumor typing
- Prognostic assessment needs biomarker confirmation
Benefits of the Immunohistochemistry HBME1 Test
Choosing the HBME1 test provides numerous advantages for both patients and healthcare providers:
- Accurate Diagnosis: Provides definitive identification of mesothelioma and specific cancer subtypes
- Treatment Guidance: Helps oncologists select the most effective therapeutic approaches
- Prognostic Value: Offers insights into disease progression and potential outcomes
- Minimized Misdiagnosis: Reduces the risk of incorrect cancer classification
- Comprehensive Analysis: Complements other diagnostic methods for complete assessment
- Personalized Medicine: Enables tailored treatment strategies based on specific biomarker profiles
Understanding Your Test Results
Your HBME1 test results will be interpreted by experienced pathologists and presented in a comprehensive report:
- Positive Result: Indicates presence of HBME1 antigen, typically associated with mesothelioma or specific epithelial tumors
- Negative Result: Suggests absence of the biomarker, helping rule out certain cancer types
- Staining Pattern: The distribution and intensity of staining provide additional diagnostic information
- Clinical Correlation: Results are interpreted in context with other clinical and pathological findings
- Follow-up Recommendations: Your report will include guidance on next steps and additional testing if needed
Test Pricing and Availability
| Test Name | Discount Price | Regular Price |
|---|---|---|
| Immunohistochemistry HBME1 Test | $88 USD | $112 USD |
Turnaround Time
- Sample Acceptance: Daily by 6 PM
- Block Processing: 5 days
- Tissue Biopsy: 5 days
- Large Complex Tissue: 7 days
Sample Requirements
For accurate testing, please provide:
- Tumor tissue preserved in 10% formal-saline OR formalin-fixed paraffin-embedded block
- Ship samples at room temperature with proper packaging
- Include complete clinical documentation: Histopathology report, biopsy site information, and detailed clinical history
Nationwide Accessibility
GGC DNA maintains comprehensive testing facilities across the United States, with branches conveniently located in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our nationwide network ensures that patients receive consistent, high-quality diagnostic services regardless of location.
Take Control of Your Health Today
Don’t let diagnostic uncertainty delay your treatment journey. The Immunohistochemistry HBME1 Test provides the clarity needed for effective cancer management and personalized care planning. Our team of specialized pathologists and oncology experts are ready to assist you with comprehensive diagnostic services and professional guidance.
Book your Immunohistochemistry HBME1 Test now or call our dedicated healthcare line at +1(267) 388-9828 to schedule your appointment. Take the first step toward precise diagnosis and targeted treatment today.
