Immunohistochemistry Estrogen Receptor ER Test
Comprehensive Introduction to Estrogen Receptor Testing
The Immunohistochemistry Estrogen Receptor ER Test represents a cornerstone in modern breast cancer diagnostics, providing critical information that directly influences treatment strategies and patient outcomes. This advanced laboratory technique detects the presence of estrogen receptors on cancer cells, offering invaluable insights into tumor biology and therapeutic responsiveness.
Estrogen receptors are protein molecules found on certain cells that bind to estrogen hormones. When breast cancer cells express these receptors, they may grow in response to estrogen circulating in the body. The identification of ER status has revolutionized breast cancer management, enabling targeted therapies that specifically block estrogen’s effects on cancer cells.
What the Test Measures and Detects
The Immunohistochemistry Estrogen Receptor ER Test specifically identifies and quantifies the presence of estrogen receptor proteins within breast cancer tissue samples. Using specialized antibodies that bind to estrogen receptors, this test provides:
- Detection of ER protein expression in tumor cells
- Quantitative assessment of receptor density
- Nuclear localization patterns of estrogen receptors
- Percentage of cancer cells showing positive staining
- Intensity of receptor expression
This detailed analysis helps pathologists determine whether the cancer is ER-positive (likely to respond to hormone therapy) or ER-negative (unlikely to benefit from anti-estrogen treatments).
Who Should Consider This Test
This essential diagnostic test is recommended for individuals in the following circumstances:
Primary Diagnostic Scenarios
- Newly diagnosed breast cancer patients
- Patients with invasive breast carcinoma
- Individuals with ductal carcinoma in situ (DCIS)
- Patients considering neoadjuvant therapy
Clinical Indications
- Abnormal mammogram findings requiring biopsy
- Palpable breast masses or lumps
- Suspicious breast imaging results
- Family history of hormone receptor-positive breast cancer
- Metastatic breast cancer with unknown receptor status
Significant Benefits of ER Testing
Undergoing Immunohistochemistry Estrogen Receptor testing provides numerous clinical advantages:
Treatment Personalization
- Guides selection of appropriate hormone therapy
- Helps determine eligibility for targeted treatments
- Informs decisions about chemotherapy necessity
- Supports individualized treatment planning
Prognostic Information
- Provides insights into disease progression likelihood
- Helps predict response to specific therapies
- Assists in recurrence risk assessment
- Supports long-term monitoring strategies
Clinical Management Advantages
- Enables evidence-based treatment decisions
- Reduces unnecessary chemotherapy exposure
- Optimizes healthcare resource utilization
- Improves overall treatment outcomes
Understanding Your Test Results
Interpreting Immunohistochemistry Estrogen Receptor ER Test results requires professional medical expertise, but general understanding includes:
ER-Positive Results
- Indicates cancer cells have estrogen receptors
- Suggests responsiveness to hormone-blocking therapies
- Typically associated with better prognosis
- May qualify for endocrine therapy options
ER-Negative Results
- Shows absence of estrogen receptors on cancer cells
- Indicates unresponsiveness to hormone therapies
- May require alternative treatment approaches
- Often considered for different therapeutic strategies
Quantitative Interpretation
- Results typically reported as percentage of positive cells
- Staining intensity graded from weak to strong
- Nuclear localization pattern assessment
- Comprehensive scoring system evaluation
Test Pricing Information
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $42 |
| Regular Price | $48 |
Nationwide Testing Availability
GGC DNA provides comprehensive Immunohistochemistry Estrogen Receptor ER testing services across the United States. Our network includes specialized testing facilities in major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Jacksonville, Fort Worth, Columbus, San Francisco, and numerous other locations.
With daily sample processing until 6 PM and reliable turnaround times of 5 days for standard blocks and tissue biopsies (7 days for complex tissue samples), we ensure timely results for critical treatment decisions. Our experienced pathologists and oncology specialists maintain the highest standards of diagnostic accuracy.
Schedule Your Test Today
Take control of your breast cancer diagnosis and treatment planning with our advanced Immunohistochemistry Estrogen Receptor ER testing. Our dedicated team is ready to assist you with convenient scheduling, professional sample collection, and comprehensive result interpretation.
Call or WhatsApp us today at +1(267) 388-9828 to book your test or discuss your testing needs with our oncology specialists. Early and accurate diagnosis significantly improves treatment outcomes and quality of life.
Trust GGC DNA for reliable, accurate, and timely estrogen receptor testing that empowers informed medical decisions and personalized cancer care.