Immunohistochemistry Cytomegalovirus CMV Test
Comprehensive CMV Detection for Optimal Patient Care
The Immunohistochemistry Cytomegalovirus (CMV) Test represents a cutting-edge diagnostic approach for detecting active Cytomegalovirus infections in tissue specimens. This sophisticated laboratory technique utilizes specific antibodies to identify CMV antigens within cellular structures, providing clinicians with definitive evidence of viral presence and activity. As a member of the herpesvirus family, CMV poses significant health risks to immunocompromised individuals, making accurate detection essential for timely intervention and treatment optimization.
What Does the CMV Immunohistochemistry Test Measure?
This advanced diagnostic test specifically targets and identifies Cytomegalovirus antigens within tissue samples through precise antibody-antigen interactions. The test measures:
- Presence of CMV immediate-early and late antigens in infected cells
- Viral protein expression patterns within tissue architecture
- Specific cellular localization of CMV infection
- Degree of tissue involvement and viral load estimation
- Correlation between viral presence and pathological changes
Who Should Consider CMV Immunohistochemistry Testing?
High-Risk Patient Populations
This test is particularly crucial for individuals experiencing:
- Unexplained fever in immunocompromised patients
- Gastrointestinal symptoms including diarrhea, abdominal pain, or bleeding
- Visual disturbances or retinitis symptoms
- Respiratory complications with unknown etiology
- Hepatitis or liver function abnormalities
- Neurological symptoms in transplant recipients
- Suspected CMV reactivation during cancer treatment
Clinical Scenarios Requiring Testing
- Organ transplant recipients showing signs of rejection or infection
- Cancer patients undergoing chemotherapy or radiation
- HIV/AIDS patients with declining CD4 counts
- Individuals receiving immunosuppressive therapy
- Neonates with suspected congenital CMV infection
- Patients with unexplained inflammatory conditions
Significant Benefits of CMV Immunohistochemistry Testing
Diagnostic Advantages
- High Specificity: Provides definitive identification of CMV-infected cells
- Tissue Context: Preserves architectural relationships between infected and normal cells
- Early Detection: Identifies infection before widespread tissue damage occurs
- Therapeutic Guidance: Informs appropriate antiviral treatment selection
- Prognostic Value: Helps predict disease progression and treatment response
Clinical Management Benefits
- Enables targeted antiviral therapy initiation
- Prevents unnecessary broad-spectrum antibiotic use
- Reduces risk of CMV-related complications
- Improves transplant success rates
- Enhances cancer treatment outcomes
- Supports personalized medicine approaches
Understanding Your Test Results
Interpretation Guidelines
Your CMV Immunohistochemistry results will be interpreted by experienced pathologists and reported as:
Positive Results
- Strong Positive: Intense staining indicating active CMV replication
- Moderate Positive: Clear viral antigen detection requiring treatment
- Focal Positive: Limited infection that may need monitoring
Negative Results
- True Negative: No CMV antigens detected in examined tissue
- Inconclusive: Requires correlation with clinical findings
Clinical Correlation
Results should always be interpreted in the context of:
- Patient’s immune status and clinical symptoms
- Concurrent laboratory findings
- Treatment history and medications
- Overall clinical presentation
Test Pricing and Availability
| Test Description | Regular Price | Discount Price |
|---|---|---|
| Immunohistochemistry Cytomegalovirus CMV Test | $126 USD | $76 USD |
Turnaround Time
- Sample Submission: Daily by 6 PM
- Block Processing: 5 days
- Tissue Biopsy: 5 days
- Complex Tissue: 7 days
Sample Requirements and Preparation
Sample Collection
- Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block
- Ship samples at room temperature
- Include complete clinical documentation
Required Documentation
- Copy of Histopathology report
- Site of biopsy specification
- Detailed clinical history
- Relevant patient demographics
Nationwide Accessibility
We maintain comprehensive testing facilities across the United States, with convenient locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network ensures timely sample processing and rapid result delivery regardless of your location.
Take Action for Better Health Outcomes
Don’t let uncertainty compromise patient care. The Immunohistochemistry CMV Test provides the definitive answers needed for effective treatment planning and improved clinical outcomes. Our team of specialized pathologists and laboratory professionals ensure the highest standards of accuracy and reliability in every test performed.
Ready to schedule your test? Contact us today at +1(267) 388-9828 or book your appointment online. Take the first step toward precise diagnosis and targeted treatment with our advanced CMV detection services.
