Immunohistochemistry CDX2 Test: Advanced Cancer Diagnosis and Staging
Understanding the Immunohistochemistry CDX2 Test
The Immunohistochemistry CDX2 Test represents a cutting-edge diagnostic approach in modern oncology, specifically designed to detect the presence of CDX2 protein markers in tissue samples. This specialized test plays a pivotal role in cancer diagnosis, particularly for gastrointestinal malignancies, by providing pathologists and oncologists with critical information about tumor characteristics and origins.
CDX2 is a transcription factor protein that serves as a specific marker for intestinal epithelial cells. Its presence or absence in tumor tissue provides valuable insights into the cellular origin of cancers, helping clinicians make accurate diagnoses and develop targeted treatment strategies. The test utilizes advanced immunohistochemistry techniques to visualize CDX2 protein expression patterns in formalin-fixed paraffin-embedded tissue sections.
What the CDX2 Test Measures and Detects
The Immunohistochemistry CDX2 Test specifically measures the expression levels and distribution patterns of CDX2 protein within tumor tissue samples. This sophisticated diagnostic tool provides several key insights:
- Intestinal Differentiation: Detects whether tumor cells show characteristics of intestinal tissue origin
- Cancer Classification: Helps distinguish between different types of gastrointestinal cancers
- Tumor Origin Identification: Determines whether metastatic tumors originated from colorectal sources
- Diagnostic Confirmation: Provides additional evidence for colorectal cancer diagnosis
- Treatment Guidance: Informs decisions about targeted therapies and treatment approaches
Who Should Consider the CDX2 Test?
This specialized diagnostic test is particularly important for patients presenting with specific clinical scenarios and symptoms:
Primary Diagnostic Applications
- Patients with suspected colorectal cancer based on clinical symptoms or imaging findings
- Individuals with gastrointestinal symptoms including persistent abdominal pain, changes in bowel habits, or unexplained weight loss
- Patients with positive fecal occult blood tests or abnormal colonoscopy findings
- Individuals with family history of colorectal cancer or genetic predisposition
Secondary Diagnostic Applications
- Patients with metastatic cancer of unknown primary origin
- Cases requiring differentiation between colorectal cancer and other gastrointestinal malignancies
- Patients being evaluated for targeted therapy eligibility
- Individuals requiring confirmation of cancer diagnosis before treatment initiation
Clinical Benefits of CDX2 Testing
Undergoing the Immunohistochemistry CDX2 Test offers numerous advantages for both patients and healthcare providers:
Diagnostic Precision
- Provides definitive evidence of intestinal differentiation in tumor cells
- Enables accurate classification of gastrointestinal malignancies
- Reduces diagnostic uncertainty and improves diagnostic confidence
- Supports comprehensive cancer staging and prognosis assessment
Treatment Optimization
- Guides selection of appropriate chemotherapy regimens
- Helps determine eligibility for targeted biological therapies
- Informs decisions about surgical approaches and treatment sequencing
- Supports personalized medicine approaches based on tumor characteristics
Prognostic Value
- Provides information about tumor behavior and potential aggressiveness
- Helps predict response to specific treatment modalities
- Supports risk stratification and follow-up planning
- Contributes to comprehensive cancer management strategies
Understanding Your CDX2 Test Results
Interpreting CDX2 test results requires professional medical expertise, but understanding the general implications can help patients participate more actively in their care:
Positive CDX2 Expression
- Strong Positive: Typically indicates colorectal origin and supports diagnosis of colorectal adenocarcinoma
- Moderate Positive: Suggests intestinal differentiation and may help classify tumor types
- Focal Positive: May indicate heterogeneous tumor characteristics requiring additional evaluation
Negative CDX2 Expression
- Complete Negative: Suggests non-colorectal origin or specific subtypes of colorectal cancer
- Weak Negative: May require correlation with other diagnostic markers and clinical findings
Clinical Correlation
Your healthcare provider will interpret CDX2 results in the context of:
- Other immunohistochemistry markers and pathology findings
- Clinical presentation and symptom history
- Imaging studies and laboratory test results
- Overall cancer staging and treatment considerations
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $88 |
| Regular Price | $126 |
Turnaround Time
- Sample Submission: Daily by 6 PM
- Report for Block: 5 days
- Tissue Biopsy: 5 days
- Tissue Large Complex: 7 days
Sample Requirements
Submit tumor tissue in 10% formal-saline OR formalin fixed paraffin embedded block. Ship at room temperature. Provide a copy of the Histopathology report, Site of biopsy and Clinical history.
Nationwide Availability and Booking
GGC DNA maintains comprehensive diagnostic facilities across the United States, with specialized centers in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network of certified pathology laboratories ensures consistent, high-quality testing standards nationwide.
Our experienced team of oncologists, pathologists, and laboratory specialists work collaboratively to provide accurate, timely results that support optimal patient care. We understand the urgency of cancer diagnosis and strive to deliver reliable diagnostic information to guide treatment decisions.
Take Action for Your Health
Early and accurate cancer diagnosis is crucial for successful treatment outcomes. The Immunohistochemistry CDX2 Test provides essential information that can significantly impact your treatment journey and overall prognosis.
Ready to schedule your test or have questions?
Call our dedicated healthcare team at +1(267) 388-9828 or book your appointment online today. Our specialists are available to discuss your testing needs, answer questions about the procedure, and help coordinate sample collection and processing.
Don’t delay critical diagnostic testing. Contact GGC DNA now to schedule your Immunohistochemistry CDX2 Test and take the first step toward comprehensive cancer diagnosis and personalized treatment planning.
