Immunohistochemistry Arginase-1 Test: Advanced Liver Cancer Detection
Understanding the Immunohistochemistry Arginase-1 Test
The Immunohistochemistry Arginase-1 Test represents a cutting-edge diagnostic approach in cancer pathology, specifically designed to identify hepatocellular carcinoma (HCC) with exceptional precision. This sophisticated laboratory technique utilizes specialized antibodies to detect the presence of arginase-1, a liver-specific enzyme that serves as a highly reliable biomarker for liver cell origin in tumor tissues.
As a crucial tool in modern oncology, this test provides pathologists and oncologists with definitive evidence to distinguish primary liver cancers from metastatic tumors or other malignancies that may involve the liver. The test’s clinical significance lies in its ability to confirm hepatocellular differentiation, which directly impacts treatment decisions, prognosis assessment, and therapeutic strategy development.
What Does the Test Measure and Detect?
The Immunohistochemistry Arginase-1 Test specifically measures the expression of arginase-1 protein within tissue samples. This enzyme is predominantly expressed in hepatocytes, making it an excellent marker for:
- Confirming hepatocellular carcinoma diagnosis
- Differentiating primary liver tumors from metastatic cancers
- Identifying hepatocyte origin in poorly differentiated tumors
- Supporting differential diagnosis of liver masses
- Providing evidence for treatment planning in liver cancer cases
The test employs advanced immunohistochemical staining techniques that visualize arginase-1 protein distribution within tissue architecture, allowing pathologists to assess both the presence and pattern of expression, which contributes to diagnostic accuracy.
Who Should Consider This Test?
Clinical Indications and Symptoms
This specialized test is recommended for patients presenting with:
- Unexplained liver masses or lesions detected on imaging studies
- Suspected hepatocellular carcinoma based on clinical presentation
- Elevated alpha-fetoprotein (AFP) levels with inconclusive imaging
- Liver tumors of uncertain origin requiring definitive diagnosis
- Patients with risk factors for liver cancer including chronic hepatitis B or C, cirrhosis, or non-alcoholic fatty liver disease
- Metastatic cancer of unknown primary origin involving the liver
- Differentiation between primary and secondary liver malignancies
Patient Populations at Risk
Individuals with chronic liver conditions, family history of liver cancer, or those exhibiting symptoms such as unexplained weight loss, abdominal pain, jaundice, or abnormal liver function tests should discuss this testing option with their healthcare provider.
Benefits of Taking the Immunohistochemistry Arginase-1 Test
Choosing this advanced diagnostic test offers numerous clinical advantages:
- High Diagnostic Accuracy: Provides >90% sensitivity and specificity for hepatocellular carcinoma detection
- Treatment Guidance: Results directly influence therapeutic decisions and treatment protocols
- Prognostic Value: Helps assess disease progression and potential treatment response
- Minimally Invasive: Utilizes existing biopsy tissue, avoiding additional procedures
- Cost-Effective: Priced at only $88 USD, making advanced diagnostics accessible
- Rapid Turnaround: Results typically available within 5 days for timely clinical decisions
- Comprehensive Analysis: Complements other diagnostic modalities for complete assessment
Understanding Your Test Results
Interpretation Guidelines
Your test results will be interpreted by board-certified pathologists and typically fall into these categories:
- Positive Result: Strong cytoplasmic staining indicates hepatocellular differentiation, supporting hepatocellular carcinoma diagnosis
- Negative Result: Absence of staining suggests non-hepatocellular origin, guiding investigation toward other tumor types
- Focal/Patchy Staining: May indicate well-differentiated HCC or specific hepatocellular subtypes
- Intensity Assessment: Staining intensity correlates with arginase-1 expression levels
Clinical Correlation
It’s essential to understand that test results are interpreted in the context of your complete clinical picture, including imaging findings, laboratory values, and medical history. Your healthcare provider will explain how these results impact your diagnosis and treatment plan.
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $88 |
| Regular Price | $140 |
Turnaround Time
- Sample Acceptance: Daily by 6 PM
- Standard Tissue Block: 5 days
- Tissue Biopsy: 5 days
- Large Complex Tissue: 7 days
Sample Requirements
Submit tumor tissue in 10% formal-saline OR formalin-fixed paraffin-embedded block. Ship at room temperature. Please provide a copy of the histopathology report, site of biopsy, and complete clinical history.
Nationwide Accessibility
We have diagnostic branches conveniently located across all major cities in the United States, including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our nationwide network ensures that advanced cancer diagnostics are accessible to patients throughout the country.
Take Action for Your Health
Early and accurate diagnosis is crucial for effective cancer management. The Immunohistochemistry Arginase-1 Test provides the definitive information needed to guide your treatment journey. Don’t delay in obtaining the clarity you need for informed medical decisions.
Book Your Test Today: Call or WhatsApp us at +1(267) 388-9828 to schedule your Immunohistochemistry Arginase-1 Test. Our dedicated team is ready to assist you with test scheduling, sample collection guidance, and answer any questions you may have about the testing process.
Take the first step toward precise diagnosis and personalized treatment planning. Contact us now to secure your discounted test at only $88 USD and benefit from our expert pathology services.
