IL12A Gene Interleukin 12A Deficiency NGS Genetic DNA Test
Comprehensive Genetic Analysis for Immune System Disorders
The IL12A Gene Interleukin 12A Deficiency NGS Genetic DNA Test represents a breakthrough in precision medicine for diagnosing inherited immune system disorders. This advanced genetic test specifically targets the IL12A gene, which plays a critical role in regulating immune responses and protecting against intracellular pathogens. Using state-of-the-art Next-Generation Sequencing technology, our test provides unparalleled accuracy in identifying genetic mutations that compromise immune function.
What Does the IL12A Gene Test Measure?
This sophisticated genetic analysis detects mutations and variations in the IL12A gene that encodes the p35 subunit of interleukin-12. The test specifically identifies:
- Point mutations affecting IL12A gene function
- Insertions and deletions disrupting protein structure
- Splice site variants altering gene expression
- Regulatory region mutations affecting IL-12 production
- Compound heterozygous mutations causing complete deficiency
Who Should Consider This Genetic Test?
This test is particularly recommended for individuals experiencing:
- Recurrent or severe mycobacterial infections (including BCG complications)
- Persistent salmonella infections without clear cause
- Family history of primary immunodeficiency disorders
- Unexplained chronic inflammatory conditions
- Children with failure to thrive and recurrent infections
- Patients with unusual susceptibility to intracellular pathogens
- Individuals with autoimmune manifestations alongside infection susceptibility
Clinical Benefits of IL12A Genetic Testing
Undergoing IL12A genetic testing provides numerous clinical advantages:
- Precise Diagnosis: Confirms genetic basis of immune deficiency
- Personalized Treatment: Guides targeted therapeutic interventions
- Family Planning: Enables informed reproductive decisions
- Prognostic Information: Helps predict disease progression
- Therapeutic Monitoring: Assists in evaluating treatment efficacy
- Genetic Counseling: Provides comprehensive family risk assessment
Understanding Your Test Results
Your genetic test results will be thoroughly explained by our certified genetic counselors:
- Normal Result: No pathogenic mutations detected in IL12A gene
- Pathogenic Mutation: Identified genetic variant known to cause deficiency
- Variant of Uncertain Significance: Genetic change requiring further investigation
- Carrier Status: Single mutation copy with implications for offspring
All positive results include detailed interpretation and recommendations for clinical management, including potential treatments such as interferon-gamma therapy or hematopoietic stem cell transplantation.
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified collection centers ensures accessible genetic testing services nationwide.
Take Control of Your Immune Health Today
Don’t let unexplained immune deficiencies compromise your quality of life. Our IL12A Gene Interleukin 12A Deficiency NGS Genetic DNA Test provides the clarity needed for effective medical management. With results available in just 3-4 weeks and multiple sample collection options including blood, extracted DNA, or FTA card blood spots, getting tested has never been more convenient.
Ready to schedule your genetic test? Call our dedicated genetic counseling team at +1(267) 388-9828 or book your appointment online today. Take the first step toward understanding your immune health with confidence and precision.
