IKBKB Gene Immunodeficiency Type 15 NGS Genetic DNA Test
Comprehensive Genetic Analysis for Immune System Disorders
The IKBKB Gene Immunodeficiency Type 15 NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for immune system disorders. This advanced test specifically targets mutations in the IKBKB gene, which plays a critical role in regulating the NF-κB signaling pathway – a fundamental mechanism controlling immune responses, inflammation, and cell survival. When this gene malfunctions, it can lead to severe combined immunodeficiency type 15, a rare but serious condition affecting multiple body systems.
What Does This Test Measure and Detect?
Our state-of-the-art NGS (Next-Generation Sequencing) technology provides comprehensive analysis of the IKBKB gene to identify:
- Point mutations and single nucleotide variations
- Insertions and deletions affecting gene function
- Copy number variations and structural abnormalities
- Pathogenic variants associated with immunodeficiency type 15
- Novel mutations that may impact NF-κB signaling pathways
The test examines the entire coding region of the IKBKB gene, ensuring comprehensive coverage of potential mutation sites that could compromise immune system integrity.
Who Should Consider This Genetic Test?
This specialized genetic test is recommended for individuals experiencing:
- Recurrent severe bacterial, viral, or fungal infections
- Unexplained autoimmune conditions affecting multiple systems
- Chronic inflammatory skin disorders unresponsive to conventional treatments
- Family history of primary immunodeficiency disorders
- Unexplained bone abnormalities or skeletal issues
- Multiple hospitalizations for infectious diseases in childhood
- Failure to thrive or developmental delays with immune complications
- Consanguineous family background with immune-related conditions
Clinical Benefits of IKBKB Genetic Testing
Undergoing this comprehensive genetic analysis provides numerous clinical advantages:
- Accurate Diagnosis: Precise identification of the underlying genetic cause of immune dysfunction
- Personalized Treatment: Tailored therapeutic approaches based on specific genetic findings
- Family Planning Guidance: Essential information for genetic counseling and reproductive decisions
- Early Intervention: Opportunity for proactive management before severe complications develop
- Disease Monitoring: Baseline for tracking disease progression and treatment effectiveness
- Research Contribution: Participation in advancing understanding of rare immune disorders
Understanding Your Test Results
Our comprehensive genetic counseling support helps you interpret your results effectively:
- Positive Result: Indicates the presence of pathogenic IKBKB gene mutations, confirming immunodeficiency type 15 diagnosis and guiding targeted treatment strategies
- Negative Result: Suggests absence of known pathogenic mutations in the IKBKB gene, though other genetic or environmental factors may still contribute to symptoms
- Variant of Uncertain Significance: Identifies genetic changes with unclear clinical implications, requiring ongoing monitoring and potential family studies
- Carrier Status: Determines if you carry one copy of a mutated gene, important for family planning decisions
Test Pricing Information
| Test Component | Price (USD) |
|---|---|
| IKBKB Gene Immunodeficiency Type 15 NGS Genetic DNA Test – Discount Price | $500 |
| IKBKB Gene Immunodeficiency Type 15 NGS Genetic DNA Test – Regular Price | $700 |
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our network of certified genetic counselors and medical professionals ensures consistent, high-quality care regardless of location.
Pre-Test Preparation Requirements
To ensure optimal testing conditions and accurate results, please prepare:
- Complete clinical history documentation for the patient undergoing testing
- Genetic counseling session to create detailed pedigree chart of family members affected by IKBKB-related conditions
- Discussion of testing implications, benefits, and potential outcomes with our genetic specialists
- Review of insurance coverage and payment options if applicable
Take Control of Your Genetic Health Today
Don’t let uncertainty about your immune health continue. Our IKBKB Gene Immunodeficiency Type 15 NGS Genetic DNA Test provides the clarity you need for informed medical decisions. With results typically available within 3-4 weeks and multiple sample collection options including blood, extracted DNA, or blood spots on FTA cards, getting tested has never been more convenient.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic testing appointment and take the first step toward understanding your immune system health.
