IFNGR1 Gene Mycobacterial Infection Atypical Familial Disseminated NGS Genetic DNA Test
Understanding IFNGR1 Gene Testing
The IFNGR1 Gene Mycobacterial Infection Atypical Familial Disseminated NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for immunodeficiency disorders. This advanced test specifically targets mutations in the interferon-gamma receptor 1 (IFNGR1) gene, which plays a critical role in the body’s immune defense against intracellular pathogens, particularly mycobacteria.
What Does This Test Measure?
This comprehensive genetic analysis utilizes Next Generation Sequencing (NGS) technology to detect:
- Pathogenic variants in the IFNGR1 gene affecting interferon-gamma signaling
- Mutations responsible for Mendelian Susceptibility to Mycobacterial Diseases (MSMD)
- Genetic abnormalities leading to impaired cellular immunity
- Inherited patterns of immunodeficiency affecting mycobacterial defense mechanisms
Who Should Consider This Test?
This genetic test is particularly recommended for individuals experiencing:
- Recurrent or severe atypical mycobacterial infections
- Disseminated infections without typical immune compromise
- Family history of mycobacterial disease susceptibility
- Unexplained recurrent infections in childhood
- Poor response to standard antimicrobial therapies
- Clinical features of primary immunodeficiency disorders
Clinical Indications and Symptoms
Patients presenting with the following symptoms should consider this genetic evaluation:
- Persistent fever of unknown origin
- Recurrent lymphadenopathy
- Chronic skin lesions or granulomatous dermatitis
- Hepatosplenomegaly with infection
- Bone lesions associated with mycobacterial infection
- Family members affected by similar infection patterns
Benefits of IFNGR1 Genetic Testing
Undergoing this advanced genetic analysis provides numerous clinical advantages:
- Accurate Diagnosis: Precise identification of genetic mutations causing immunodeficiency
- Personalized Treatment: Tailored therapeutic approaches based on genetic findings
- Family Planning: Genetic counseling for inheritance patterns and recurrence risks
- Early Intervention: Proactive management strategies for at-risk family members
- Comprehensive Care: Integration with dermatology, immunology, and genetic specialties
Understanding Your Test Results
Our comprehensive genetic counseling service helps interpret your results:
- Positive Result: Indicates presence of pathogenic IFNGR1 mutations requiring specialized immunological management
- Negative Result: Suggests alternative causes for recurrent infections should be investigated
- Variant of Uncertain Significance: Requires additional family studies and clinical correlation
- Carrier Status: Important information for family planning and genetic counseling
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | IFNGR1 Gene Mycobacterial Infection Atypical Familial Disseminated NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next Generation Sequencing (NGS) Technology |
Pre-Test Requirements
Before scheduling your test, please ensure:
- Complete clinical history documentation
- Genetic counseling session to create family pedigree chart
- Discussion of testing implications with healthcare provider
- Understanding of potential outcomes and management options
Nationwide Testing Availability
We proudly offer this specialized genetic testing across the United States with convenient locations in major metropolitan areas including New York, Los Angeles, Chicago, Miami, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and many other cities. Our network of certified genetic counselors and medical professionals ensures accessible, high-quality care nationwide.
Take Control of Your Genetic Health
Don’t let unexplained infections compromise your quality of life. Our IFNGR1 genetic testing provides the answers you need for proper diagnosis and targeted treatment. With advanced NGS technology and comprehensive genetic analysis, we deliver accurate results that can transform your healthcare journey.
Ready to schedule your test? Call our genetic specialists today at +1(267) 388-9828 or book your appointment online. Take the first step toward understanding your genetic predisposition to mycobacterial infections and receive personalized care from our expert team.
