IDH1 Gene Selective Sequencing of Exon 4 NGS Genetic DNA Test
Comprehensive Introduction to IDH1 Genetic Testing
The IDH1 Gene Selective Sequencing of Exon 4 NGS Genetic DNA Test represents a breakthrough in precision oncology, offering targeted analysis of one of the most critical genetic markers in cancer biology. This advanced diagnostic tool utilizes next-generation sequencing technology to specifically examine exon 4 of the IDH1 gene, where the majority of clinically significant mutations occur. The IDH1 gene encodes isocitrate dehydrogenase 1, an enzyme involved in cellular metabolism, and mutations in this gene have been identified as key drivers in various cancer types, particularly central nervous system tumors and hematological malignancies.
What This Test Measures and Detects
This specialized genetic test focuses on identifying specific mutations within exon 4 of the IDH1 gene, including:
- R132H mutation – the most common IDH1 mutation in gliomas
- Other R132 variants including R132C, R132G, R132L, and R132S
- Additional exon 4 mutations that may impact enzyme function
- Genetic alterations affecting the active site of the IDH1 enzyme
Who Should Consider This Genetic Test
This test is particularly recommended for individuals with:
- Newly diagnosed gliomas or brain tumors
- Suspected or confirmed acute myeloid leukemia (AML)
- Chondrosarcoma or other bone tumors
- Family history of IDH1-related cancers
- Patients being evaluated for targeted therapy options
- Individuals with unexplained neurological symptoms
Significant Benefits of IDH1 Genetic Testing
Undergoing IDH1 genetic testing provides numerous advantages for patients and healthcare providers:
- Precision Treatment Planning: Identifies eligibility for targeted therapies specifically designed for IDH1-mutated cancers
- Prognostic Information: Helps predict disease progression and overall survival outcomes
- Diagnostic Clarity: Aids in distinguishing between different types of brain tumors and cancers
- Personalized Medicine: Enables tailored treatment approaches based on individual genetic profiles
- Clinical Trial Eligibility: Opens doors to novel therapeutic options and research studies
Understanding Your Test Results
Your IDH1 genetic test results will be carefully interpreted by our team of genetic specialists and oncologists:
- Positive Result: Indicates the presence of an IDH1 mutation, which may guide targeted treatment decisions and provide prognostic information
- Negative Result: Suggests no detectable IDH1 mutations were found in the tested region
- Variant of Uncertain Significance: Some genetic changes may require additional analysis or family studies for proper interpretation
All results are accompanied by comprehensive genetic counseling to ensure you fully understand the implications for your health and treatment options.
Test Pricing and Details
| Test Feature | Details |
|---|---|
| Test Name | IDH1 Gene Selective Sequencing of Exon 4 NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
Nationwide Testing Availability
We proudly offer comprehensive genetic testing services across the United States, with convenient locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Jacksonville, Fort Worth, Columbus, Charlotte, San Francisco, Indianapolis, Seattle, Denver, Washington DC, Boston, El Paso, Nashville, Detroit, Oklahoma City, Portland, Las Vegas, Memphis, Louisville, Baltimore, and Milwaukee. Our network of certified testing facilities ensures accessible, reliable genetic testing for patients nationwide.
Take the Next Step in Your Health Journey
Don’t leave your genetic health to chance. Our IDH1 genetic testing provides critical information that can significantly impact your treatment decisions and overall health outcomes. With our discounted rate of $500 USD and comprehensive genetic counseling services, you’ll receive the expert guidance and precise results you need to make informed healthcare decisions.
Ready to schedule your IDH1 genetic test? Call our dedicated genetic specialists today at +1(267) 388-9828 or book your appointment online. Take control of your genetic health with the precision and expertise of General Genetics Corporation.
