ICOS Gene Immunodeficiency Common Variable Type 1 NGS Genetic DNA Test
Comprehensive Genetic Testing for Immune System Disorders
The ICOS Gene Immunodeficiency Common Variable Type 1 NGS Genetic DNA Test represents a breakthrough in precision medicine for diagnosing inherited immune deficiencies. This advanced genetic screening utilizes state-of-the-art Next-Generation Sequencing (NGS) technology to identify mutations in the ICOS (Inducible T-cell Costimulator) gene, which plays a critical role in regulating immune responses and maintaining immune system homeostasis.
What Does This Test Measure and Detect?
This sophisticated genetic analysis specifically targets the ICOS gene located on chromosome 2q33.2, examining it for pathogenic variants that disrupt normal immune function. The test detects:
- Point mutations, insertions, and deletions in the ICOS gene
- Single nucleotide polymorphisms (SNPs) affecting protein function
- Genetic variations that impair T-cell activation and antibody production
- Mutations leading to defective germinal center formation
- Variants associated with impaired B-cell differentiation
Who Should Consider This Test?
This genetic test is particularly recommended for individuals experiencing:
- Recurrent bacterial, viral, or fungal infections requiring frequent antibiotic treatments
- Chronic respiratory infections including pneumonia, bronchitis, or sinusitis
- Autoimmune manifestations such as rheumatoid arthritis, lupus, or thyroid disorders
- Gastrointestinal complications including chronic diarrhea or malabsorption
- Dermatological conditions like eczema, psoriasis, or chronic skin infections
- Family history of immune deficiencies or unexplained infant deaths
- Delayed diagnosis despite multiple medical consultations
- Poor response to conventional treatments for recurrent infections
Clinical Benefits of Genetic Testing
Undergoing the ICOS Gene Immunodeficiency Test provides numerous clinical advantages:
- Precise Diagnosis: Eliminates diagnostic uncertainty and enables targeted treatment approaches
- Personalized Treatment: Guides immunoglobulin replacement therapy and prophylactic antibiotic regimens
- Family Planning: Provides crucial information for genetic counseling and reproductive decisions
- Early Intervention: Facilitates proactive management to prevent serious complications
- Comprehensive Care: Coordinates multidisciplinary care involving immunologists, dermatologists, and genetic specialists
Understanding Your Test Results
Your genetic test results will be carefully interpreted by our team of certified genetic counselors and immunology specialists:
- Positive Result: Indicates the presence of pathogenic ICOS gene mutations, confirming Common Variable Immunodeficiency Type 1 diagnosis
- Negative Result: Suggests absence of known ICOS mutations, though other immune deficiency causes may need investigation
- Variant of Uncertain Significance: Requires additional family studies and clinical correlation for proper interpretation
- Carrier Status: Identifies individuals who may pass the condition to offspring while remaining asymptomatic themselves
Test Pricing and Availability
| Test Feature | Details |
|---|---|
| Test Name | ICOS Gene Immunodeficiency Common Variable Type 1 NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
Nationwide Testing Availability
We have conveniently located testing centers across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our network ensures accessible genetic testing services for patients throughout the country.
Take Control of Your Health Today
Don’t let unexplained immune symptoms compromise your quality of life. Our comprehensive ICOS Gene Immunodeficiency Test provides the answers you need for proper diagnosis and effective treatment. Our experienced genetic counselors are available to discuss your results and guide you through next steps.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic testing appointment or to speak with our genetic counseling team. Take the first step toward understanding your immune health and achieving better medical outcomes.
