HTRA1 Gene CARASIL NGS Genetic DNA Test
Comprehensive Genetic Analysis for Hereditary Small Vessel Disease
The HTRA1 Gene CARASIL NGS Genetic DNA Test represents a breakthrough in neurological genetic testing, specifically designed to identify mutations in the HTRA1 gene that cause Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukencephalopathy (CARASIL). This sophisticated diagnostic tool utilizes next-generation sequencing technology to provide accurate, comprehensive analysis of genetic variations associated with this rare but devastating neurological condition.
What Does the HTRA1 Gene CARASIL Test Measure?
This advanced genetic test specifically targets and analyzes the HTRA1 (High Temperature Requirement A Serine Peptidase 1) gene, which plays a critical role in maintaining the integrity of cerebral blood vessels. The test detects:
- Pathogenic mutations in the HTRA1 gene associated with CARASIL
- Single nucleotide variants and small insertions/deletions
- Compound heterozygous mutations requiring inheritance from both parents
- Genetic markers for early-onset cerebral small vessel disease
- Risk factors for progressive neurological deterioration
Who Should Consider This Genetic Test?
This test is particularly recommended for individuals experiencing or at risk for:
- Early-onset stroke symptoms before age 40
- Progressive cognitive decline and memory issues
- Recurrent headaches and migraine episodes
- Mood changes, depression, or personality alterations
- Gait disturbances and mobility challenges
- Family history of young-onset cerebrovascular disease
- Unexplained white matter changes on brain imaging
- Multiple family members with similar neurological symptoms
Significant Benefits of HTRA1 Genetic Testing
Undergoing the HTRA1 Gene CARASIL NGS Genetic DNA Test provides numerous advantages:
- Early Diagnosis: Enables prompt identification of CARASIL before severe neurological damage occurs
- Family Planning: Provides crucial information for reproductive decisions and genetic counseling
- Personalized Treatment: Guides appropriate medical management and preventive strategies
- Risk Assessment: Identifies asymptomatic family members who may carry the mutation
- Psychological Relief: Reduces uncertainty and provides clarity about neurological symptoms
- Research Contribution: Helps advance understanding of hereditary small vessel diseases
Understanding Your Test Results
Your genetic test results will be carefully interpreted by our expert genetic counselors and neurologists:
- Positive Result: Indicates the presence of pathogenic HTRA1 mutations confirming CARASIL diagnosis
- Negative Result: Suggests absence of known CARASIL-causing mutations in the HTRA1 gene
- Variant of Uncertain Significance: Requires additional family studies and clinical correlation
- Carrier Status: Identifies individuals with single mutation copies who may pass the condition to offspring
All positive results include comprehensive genetic counseling to discuss implications, management options, and family testing recommendations.
Test Pricing and Sample Requirements
| Test Component | Details |
|---|---|
| Test Name | HTRA1 Gene CARASIL NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Nationwide Accessibility and Convenient Testing
We have established testing facilities across the United States, with branches in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our nationwide network ensures that quality genetic testing is accessible to patients regardless of location.
Pre-Test Preparation and Requirements
Before undergoing the HTRA1 Gene CARASIL NGS Genetic DNA Test, patients should:
- Provide comprehensive clinical history including neurological symptoms
- Participate in genetic counseling sessions to understand test implications
- Complete family pedigree chart documenting affected relatives
- Discuss testing goals and potential outcomes with healthcare providers
- Review insurance coverage and payment options
Take Control of Your Neurological Health Today
Don’t let uncertainty about hereditary neurological conditions affect your quality of life. The HTRA1 Gene CARASIL NGS Genetic DNA Test provides definitive answers and empowers you to make informed healthcare decisions. Our team of genetic specialists, neurologists, and counselors are ready to support you through every step of the testing process.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your appointment or book your test online. Take the first step toward understanding your genetic risk for cerebral small vessel disease and secure your neurological future.
