HLA Typing Test for Donor and Recipient
Understanding HLA Typing for Transplantation Success
The HLA Typing Test for Donor and Recipient represents a cornerstone of modern transplantation medicine, providing critical genetic matching information essential for successful organ and tissue transplantation outcomes. Human Leukocyte Antigens (HLA) are proteins found on the surface of most cells in your body that help your immune system distinguish between your own cells and foreign substances. When these antigens don’t match between donor and recipient, the immune system may attack the transplanted organ or tissue, leading to rejection.
What Does the HLA Typing Test Measure?
This comprehensive test analyzes specific genetic markers in the HLA system, focusing on:
- HLA-A, HLA-B, and HLA-C antigens (Class I)
- HLA-DR, HLA-DQ, and HLA-DP antigens (Class II)
- High-resolution typing for precise matching
- Allele-level identification for optimal compatibility assessment
Who Should Consider HLA Typing?
This test is essential for individuals in the following situations:
- Patients awaiting organ transplantation (kidney, liver, heart, lung)
- Individuals requiring bone marrow or stem cell transplantation
- Family members being evaluated as potential living donors
- Patients with hematological disorders requiring donor matching
- Individuals enrolled in transplant waiting lists
- Patients with autoimmune conditions requiring transplantation assessment
Clinical Indications and Symptoms
HLA typing becomes necessary when patients present with:
- End-stage organ failure requiring transplantation
- Hematological malignancies needing bone marrow transplant
- Genetic blood disorders requiring stem cell therapy
- Severe immune deficiencies necessitating donor matching
- Chronic organ diseases progressing toward transplantation
Benefits of HLA Typing Testing
Undergoing HLA typing provides numerous advantages for transplantation success:
- Reduced Rejection Risk: Identifies compatible donors to minimize immune rejection
- Improved Transplant Outcomes: Enhances long-term graft survival rates
- Personalized Matching: Enables tailored donor selection for optimal compatibility
- Early Identification: Allows proactive donor search and preparation
- Family Screening: Facilitates evaluation of related potential donors
- Registry Compatibility: Matches patients with national donor registries
Advanced NGS Technology
Our HLA Typing Test utilizes Next-Generation Sequencing (NGS) technology, offering:
- High-resolution typing with exceptional accuracy
- Comprehensive allele identification
- Rapid turnaround time of 12-15 days
- Minimal sample requirements
- Reliable results for critical medical decisions
Understanding Your Test Results
Your HLA typing results will provide detailed information about:
- HLA Match Level: Degree of compatibility between donor and recipient
- Antigen Profiles: Specific HLA antigens identified
- Compatibility Score: Numerical assessment of match quality
- Risk Assessment: Potential for graft-versus-host disease
- Transplant Suitability: Recommendations for proceeding with transplantation
Results are typically interpreted by hematologists and transplant specialists who consider the match level in context with other clinical factors. A higher degree of HLA matching generally correlates with better transplant outcomes and reduced complication risks.
Test Information and Pricing
| Test Component | Details |
|---|---|
| Test Name | HLA Typing Test for Donor and Recipient |
| Discount Price | $400 USD |
| Regular Price | $800 USD |
| Turnaround Time | 12-15 days |
| Sample Type | 4 mL whole blood in EDTA tube OR 6 mL whole blood in ACD tube OR Buccal swab |
| Preparation | No special preparation required |
| Testing Method | Next-Generation Sequencing (NGS) |
Nationwide Testing Availability
General Genetics Corporation provides comprehensive HLA typing services across the United States, with convenient testing locations in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified laboratories ensures consistent, high-quality results regardless of your location.
Take the Next Step Toward Transplantation Success
Don’t leave your transplantation outcomes to chance. Our HLA Typing Test provides the critical genetic information needed for successful donor matching and improved transplant results. With our special discounted pricing and nationwide availability, there’s no reason to delay this essential testing.
Book your HLA Typing Test today by calling +1(267) 388-9828 or schedule your appointment online. Our dedicated team is ready to assist you with this crucial step in your transplantation journey.
