HLA DP Typing Test – Comprehensive HLA Matching for Transplantation Success
Understanding HLA DP Typing and Its Critical Role in Transplantation
The HLA DP Typing Test represents a cornerstone in modern transplant medicine, providing essential genetic information that directly impacts transplantation success rates. Human Leukocyte Antigen (HLA) DP typing specifically examines the HLA-DP region of chromosome 6, which plays a vital role in immune system recognition and response. This sophisticated genetic analysis helps medical professionals determine compatibility between organ donors and recipients, significantly reducing the risk of transplant rejection and improving long-term patient outcomes.
What Does the HLA DP Typing Test Measure?
The HLA DP Typing Test provides comprehensive analysis of two critical genetic components:
- HLA-DPA1 Gene Analysis: Examines the alpha chain of the HLA-DP molecule, which forms part of the antigen-presenting complex
- HLA-DPB1 Gene Analysis: Evaluates the beta chain that completes the HLA-DP heterodimer structure
Using the advanced Reverse Sequence-Specific Oligonucleotide Probe (SSOP) Luminex methodology, this test delivers high-resolution typing results with exceptional accuracy and reliability. The technology enables precise identification of HLA-DP alleles, providing transplant teams with detailed genetic matching information essential for successful organ transplantation.
Who Should Consider HLA DP Typing?
Primary Candidates for Testing
The HLA DP Typing Test is specifically recommended for:
- Organ Transplant Candidates: Patients awaiting kidney, liver, heart, lung, or pancreas transplantation
- Living Donor-Recipient Pairs: Individuals involved in living donor transplant programs
- Bone Marrow Transplant Patients: Those undergoing hematopoietic stem cell transplantation
- Patients with Previous Transplant Rejection: Individuals who have experienced organ rejection episodes
- High-Risk Transplant Candidates: Patients with sensitized immune systems or multiple previous transfusions
Medical Specialists Who Order This Test
- Nephrologists managing kidney transplantation programs
- Hematologists overseeing bone marrow and stem cell transplants
- Gastroenterologists involved in liver transplantation
- Transplant surgeons coordinating organ matching
- Immunologists assessing immune compatibility
Comprehensive Benefits of HLA DP Typing
Clinical Advantages for Transplant Success
- Reduced Rejection Risk: Minimizes the likelihood of acute and chronic organ rejection
- Improved Graft Survival: Enhances long-term organ function and patient survival rates
- Personalized Immunosuppression: Enables tailored medication regimens based on genetic compatibility
- Enhanced Donor Selection: Provides critical data for optimal donor-recipient matching
- Early Intervention Planning: Helps anticipate potential complications and plan preventive strategies
Patient-Specific Benefits
- Increased confidence in transplant success
- Reduced need for aggressive immunosuppressive therapy
- Lower risk of infection complications
- Improved quality of life post-transplantation
- Better long-term health outcomes
Understanding Your HLA DP Typing Results
Interpretation Guidelines
Your HLA DP Typing results will provide detailed information about your specific HLA-DP genetic profile:
- HLA-DPA1 Alleles: Identifies your specific alpha chain genetic variations
- HLA-DPB1 Alleles: Details your beta chain genetic makeup
- Compatibility Score: Indicates the degree of match with potential donors
- Risk Assessment: Evaluates potential for immune-mediated complications
What Your Results Mean
A higher degree of HLA-DP matching between donor and recipient typically correlates with:
- Lower incidence of antibody-mediated rejection
- Reduced risk of chronic allograft dysfunction
- Better response to standard immunosuppressive protocols
- Improved long-term graft function
Your transplant team will carefully review these results in conjunction with other HLA typing data to make the most informed decisions about your transplantation plan.
Test Details and Pricing
| Test Parameter | Details |
|---|---|
| Test Name | HLA DP Typing Test |
| Regular Price | $196 USD |
| Discount Price | $176 USD |
| Turnaround Time | 10-12 Days |
| Sample Type | 4 mL (3 mL min.) whole blood in 1 Lavender Top (EDTA) tube OR 6 mL (3 mL min.) whole blood in 1 Yellow Top (ACD) tube |
| Shipping Requirements | Ship refrigerated. DO NOT FREEZE |
| Required Documentation | Doctor’s prescription on letterhead with 1 photograph each of recipient and donor duly stamped AND Consent form for HLA Typing for Solid organ transplant (Form 33) |
| Test Components | DPA1, DPB1 |
| Testing Methodology | Reverse SSOP – Luminex |
Nationwide Availability and Booking
We have diagnostic centers conveniently located across the United States, serving patients in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our state-of-the-art facilities ensure consistent, high-quality testing results with rapid turnaround times.
Ready to Schedule Your HLA DP Typing Test?
Take the next critical step in your transplantation journey with confidence. Our experienced genetic counselors and transplant specialists are available to answer your questions and guide you through the testing process.
Call or WhatsApp us today at +1(267) 388-9828 to book your HLA DP Typing Test or to speak with one of our transplantation genetics specialists.
Don’t leave your transplant success to chance – ensure comprehensive HLA matching with our advanced HLA DP Typing analysis. Your journey to better transplant outcomes starts with precise genetic information.
