HLA DNA High Resolution Typing C Locus Test
Comprehensive Introduction to HLA DNA High Resolution Typing
The HLA DNA High Resolution Typing C Locus Test represents a cutting-edge genetic analysis that examines the Human Leukocyte Antigen (HLA) system, specifically focusing on the C locus with high-resolution precision. The HLA system is the most polymorphic genetic region in humans and plays a fundamental role in immune system regulation, transplantation compatibility, and autoimmune disease susceptibility. This advanced testing methodology provides unprecedented detail about your genetic makeup, enabling healthcare providers to make informed decisions regarding transplantation procedures and immune-related conditions.
What Does the HLA DNA High Resolution Typing C Locus Test Measure?
This sophisticated genetic test specifically targets and analyzes the HLA-C locus, one of the classical class I HLA genes that encode cell surface proteins essential for immune recognition. The test employs Polymerase Chain Reaction (PCR) and sequencing technologies to identify specific alleles at the HLA-C locus with high-resolution accuracy, distinguishing between closely related genetic variants that standard testing might miss.
- Identifies specific HLA-C alleles at high resolution
- Detects genetic variations in the HLA-C locus
- Provides detailed allele-level typing for transplantation matching
- Assesses immune system compatibility markers
- Evaluates genetic predisposition to certain autoimmune conditions
Who Should Consider HLA DNA High Resolution Typing?
This specialized genetic test is particularly important for individuals in specific medical situations requiring precise immune system compatibility assessment.
Primary Candidates for Testing Include:
- Patients being evaluated for organ transplantation (kidney, liver, heart, lung)
- Individuals undergoing bone marrow or stem cell transplantation assessment
- Patients with autoimmune diseases requiring HLA typing for treatment planning
- Family members of transplant recipients for donor matching
- Individuals with suspected HLA-related drug hypersensitivity reactions
- Patients with certain inflammatory conditions where HLA typing aids diagnosis
Significant Benefits of HLA DNA High Resolution Typing
Undergoing HLA DNA High Resolution Typing provides numerous advantages for patients and healthcare providers alike, particularly in transplantation medicine and autoimmune disease management.
Key Benefits Include:
- Enhanced Transplantation Success: High-resolution HLA matching significantly improves transplant outcomes and reduces rejection risks
- Precise Donor Matching: Enables accurate matching between donors and recipients for better compatibility
- Reduced Complications: Minimizes the risk of graft-versus-host disease in bone marrow transplantation
- Personalized Treatment Planning: Provides essential information for customized treatment approaches
- Comprehensive Immune Assessment: Offers detailed insight into immune system genetics
- Early Risk Identification: Helps identify potential immune-related complications before they occur
Understanding Your HLA DNA High Resolution Typing Results
Interpreting HLA DNA High Resolution Typing results requires specialized medical expertise, but understanding the basic concepts can help patients engage more effectively with their healthcare team.
Result Interpretation Guidelines:
- HLA-C Allele Identification: Results will show specific HLA-C alleles identified through high-resolution typing
- Matching Assessment: For transplantation, results indicate the degree of HLA matching between donor and recipient
- Genetic Predisposition: Certain HLA-C alleles may indicate increased susceptibility to specific autoimmune conditions
- Clinical Correlation: Results must be interpreted in the context of your overall medical condition and treatment plan
- Follow-up Consultation: Always discuss results with your hematologist or transplant specialist for proper interpretation
Test Details and Pricing Information
| Test Parameter | Details |
|---|---|
| Test Name | HLA DNA High Resolution Typing C Locus Test |
| Discount Price | $200 USD |
| Regular Price | $300 USD |
| Turnaround Time | 10-12 days |
| Sample Type | 4 mL (3 mL min.) whole blood in 1 Lavender Top (EDTA) tube OR 6 mL (3 mL min.) whole blood in 1 Yellow Top (ACD) tube OR Buccal swab collected in a sterile container |
| Shipping Instructions | Ship refrigerated. DO NOT FREEZE |
| Preparation Required | No special preparation required |
| Testing Methodology | PCR and Sequencing |
Nationwide Testing Availability
We have branches across the United States, making advanced HLA DNA High Resolution Typing accessible to patients nationwide. Our testing facilities are conveniently located in major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities throughout the USA.
Take the Next Step Toward Better Health
Don’t let uncertainty about immune compatibility stand in the way of optimal medical care. The HLA DNA High Resolution Typing C Locus Test provides the critical genetic information needed for successful transplantation outcomes and comprehensive autoimmune disease management. Our experienced team is ready to assist you with this important genetic analysis.
Book your HLA DNA High Resolution Typing C Locus Test today by calling our dedicated healthcare line at +1(267) 388-9828 or schedule your appointment online. Take control of your health journey with precise genetic information from General Genetics Corporation.
