HLA A B DRB1 Low Resolution Test
Comprehensive Introduction to HLA Genetic Testing
The HLA A B DRB1 Low Resolution test represents a cornerstone in modern genetic diagnostics, focusing on the critical human leukocyte antigen (HLA) system that governs immune response and tissue compatibility. This sophisticated genetic analysis examines specific markers within the HLA complex, which plays a fundamental role in distinguishing self from non-self antigens and orchestrating immune defense mechanisms. The importance of HLA testing extends beyond basic genetic screening, serving as an essential tool for transplantation medicine, autoimmune disease management, and personalized healthcare strategies.
What Does the HLA A B DRB1 Test Measure?
This comprehensive genetic assessment specifically targets three crucial HLA gene loci:
- HLA-A Locus: Identifies class I antigens critical for immune surveillance and viral defense
- HLA-B Locus: Detects additional class I antigens involved in immune recognition
- HLA-DRB1 Locus: Analyzes class II antigens essential for immune regulation and autoimmune responses
The low-resolution methodology provides broad antigen identification, making it ideal for initial screening and compatibility assessment in various clinical scenarios.
Technical Specifications
- Methodology: End Point PCR (Polymerase Chain Reaction)
- Sample Type: Peripheral blood (EDTA Vacutainer 2ml) or Buccal swabs (6-8 specimens)
- Turnaround Time: 10-12 business days
- Test Components: Comprehensive analysis of HLA-A, HLA-B, and HLA-DRB1 loci
Who Should Consider HLA A B DRB1 Testing?
This genetic test is particularly valuable for individuals in the following circumstances:
Transplant Candidates and Donors
- Patients awaiting organ transplantation (kidney, bone marrow, stem cell)
- Potential living donors for family members or unrelated recipients
- Bone marrow registry participants
- Stem cell transplant candidates
Autoimmune and Inflammatory Conditions
- Patients with suspected autoimmune disorders
- Individuals with family history of autoimmune diseases
- Cases of unexplained inflammatory conditions
- Rheumatoid arthritis, lupus, or multiple sclerosis evaluation
Genetic Counseling and Family Planning
- Couples with recurrent pregnancy loss
- Families with genetic disease patterns
- Individuals with suspected genetic predispositions
Significant Benefits of HLA Testing
Enhanced Transplant Success
Accurate HLA matching significantly improves transplant outcomes by reducing rejection risks and optimizing donor-recipient compatibility, leading to better long-term organ function and patient survival rates.
Personalized Medical Insights
The test provides crucial genetic information that helps healthcare providers develop targeted treatment strategies, particularly for autoimmune conditions and immune-mediated disorders.
Proactive Health Management
Understanding your HLA profile enables proactive health monitoring and early intervention strategies for conditions with genetic predispositions.
Comprehensive Genetic Assessment
This test offers a broad overview of critical immune system markers, providing valuable data for multiple clinical applications beyond transplantation.
Understanding Your Test Results
Interpretation Guidelines
Your HLA A B DRB1 Low Resolution results will provide specific antigen identifications for each tested locus. These results are typically presented as:
- HLA-A: Two alleles (one inherited from each parent)
- HLA-B: Two alleles representing your genetic profile
- HLA-DRB1: Two alleles indicating immune regulation markers
Clinical Implications
Your healthcare provider will interpret these results in the context of your specific clinical situation:
- Transplant Matching: Higher match percentages indicate better compatibility
- Disease Association: Certain HLA types correlate with specific autoimmune conditions
- Genetic Counseling: Results inform family planning and genetic risk assessment
Next Steps After Testing
Always discuss your results with a qualified healthcare professional who can provide personalized interpretation and guide appropriate next steps based on your clinical needs and test findings.
Test Pricing and Availability
| Test Name | Regular Price | Discount Price |
|---|---|---|
| HLA A B DRB1 Low Resolution | $450 USD | $338 USD |
Pre-Test Requirements
Please note that HLA A B DRB1 Low Resolution testing typically requires a doctor’s prescription. However, prescription requirements do not apply for:
- Surgery preparation cases
- Pregnancy-related testing
- International travel medical requirements
Nationwide Testing Accessibility
GGC DNA maintains comprehensive testing facilities across the United States, ensuring convenient access to HLA A B DRB1 Low Resolution testing in all major metropolitan areas including:
- New York City and surrounding regions
- Los Angeles and Southern California
- Chicago and Midwest locations
- Houston and Texas facilities
- Miami, Atlanta, Phoenix, and other key cities
Take Action for Your Health Today
Understanding your genetic profile through HLA A B DRB1 Low Resolution testing provides invaluable insights for transplantation planning, autoimmune disease assessment, and comprehensive health management. Our advanced End Point PCR methodology ensures accurate, reliable results delivered within 10-12 days.
Ready to schedule your HLA genetic testing? Contact our dedicated healthcare team today to book your appointment or discuss your testing needs. Call or WhatsApp us at +1(267) 388-9828 to speak with our genetic testing specialists and take the first step toward comprehensive genetic understanding.
Don’t wait to gain crucial insights into your immune system genetics. Book your HLA A B DRB1 Low Resolution test today and benefit from our special pricing of $338 USD while advancing your healthcare journey with confidence and clarity.
