HLA A B C DRB1 DQB1 Low Resolution Test
Comprehensive Genetic Analysis for Immune System Compatibility
The HLA A B C DRB1 DQB1 Low Resolution test represents a sophisticated genetic examination that plays a pivotal role in modern medical diagnostics. This comprehensive analysis focuses on human leukocyte antigen (HLA) genes, which are fundamental components of the human immune system. Located on chromosome 6, these genes encode proteins that help the immune system distinguish between self and non-self cells, making them crucial for immune responses, organ transplantation success, and autoimmune disease susceptibility.
What Does This Test Measure?
This advanced genetic test specifically analyzes five critical HLA gene loci:
- HLA-A, HLA-B, HLA-C: Class I HLA genes that present intracellular antigens to cytotoxic T-cells
- HLA-DRB1, HLA-DQB1: Class II HLA genes involved in presenting extracellular antigens to helper T-cells
The “low resolution” methodology provides essential genetic information by identifying broad antigen groups rather than specific alleles, making it ideal for initial screening and compatibility assessments.
Who Should Consider This Test?
This HLA genetic screening is particularly recommended for:
- Transplant Candidates: Patients awaiting organ or bone marrow transplantation
- Autoimmune Disease Patients: Individuals with conditions like rheumatoid arthritis, type 1 diabetes, or celiac disease
- Family Members: Relatives of patients requiring organ donors
- Fertility Patients: Couples experiencing recurrent pregnancy loss
- Pharmacogenetic Screening: Patients requiring specific medication compatibility assessment
Key Benefits of HLA Testing
- Transplant Success Optimization: Significantly improves organ and tissue matching
- Disease Risk Assessment: Identifies genetic predispositions to autoimmune conditions
- Personalized Medicine: Enables tailored treatment approaches based on genetic profile
- Family Planning: Provides valuable information for genetic counseling
- Early Intervention: Facilitates proactive healthcare management
Understanding Your Test Results
Your HLA test results will provide detailed information about your genetic makeup at the five tested loci. The report typically includes:
- Specific HLA types identified for each gene locus
- Risk assessment for HLA-associated conditions
- Interpretive guidance from genetic specialists
>li>Compatibility scoring for transplant matching
It’s essential to discuss your results with a healthcare provider who can provide context-specific interpretation and recommend appropriate next steps based on your individual health circumstances.
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | HLA A B C DRB1 DQB1 Low Resolution |
| Discount Price | $450 USD |
| Regular Price | $600 USD |
| Turnaround Time | 10-12 days |
| Sample Type | Peripheral blood / Buccal swabs (6-8 no.) |
| Test Components | EDTA Vacutainer (2ml) |
| Testing Method | End Point PCR |
Pre-Test Instructions
The HLA A, B, C, DRB1, DQB1 Low Resolution test requires a Doctor’s prescription for most cases. However, prescription requirements do not apply for:
- Surgical preparation cases
- Pregnancy-related testing
- Individuals planning international travel
Nationwide Accessibility
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art laboratories ensure consistent, reliable results regardless of your location.
Take Control of Your Genetic Health Today
Understanding your HLA profile can provide invaluable insights into your immune system function and genetic predispositions. Whether you’re preparing for a medical procedure, managing an autoimmune condition, or simply seeking comprehensive genetic information, our HLA testing services offer the precision and reliability you deserve.
Ready to schedule your HLA A B C DRB1 DQB1 Low Resolution test? Contact our genetic specialists today at +1(267) 388-9828 or book your appointment online. Our team is available to answer your questions and guide you through the testing process with compassion and expertise.

