HBB Gene Sickle Cell Anemia NGS Genetic DNA Test
Comprehensive Genetic Testing for Sickle Cell Disease
The HBB Gene Sickle Cell Anemia NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for sickle cell disease, utilizing state-of-the-art Next Generation Sequencing technology to provide comprehensive analysis of the HBB gene. This advanced testing method offers unprecedented accuracy in detecting genetic mutations responsible for sickle cell anemia, a serious inherited blood disorder affecting millions worldwide.
What Does This Test Measure?
This sophisticated genetic test specifically analyzes the HBB (Hemoglobin Subunit Beta) gene located on chromosome 11, which encodes the beta-globin chain of hemoglobin. The test detects:
- Point mutations in the HBB gene that cause sickle cell disease
- Various genetic variants including the HbS mutation (Glu6Val)
- Carrier status for sickle cell trait
- Compound heterozygous states with other hemoglobinopathies
- Rare HBB gene mutations that may affect disease severity
Who Should Consider This Test?
This genetic screening is recommended for individuals experiencing symptoms or with risk factors including:
- Family history of sickle cell disease or trait
- Unexplained episodes of severe pain (sickle cell crises)
- Chronic anemia with fatigue and weakness
- Frequent infections or susceptibility to serious bacterial infections
- Delayed growth or puberty in children
- Vision problems or retinal damage
- Individuals from ethnic backgrounds with higher sickle cell prevalence
- Couples planning pregnancy with known family history
Key Benefits of Genetic Testing
Choosing the HBB Gene Sickle Cell Anemia NGS Genetic DNA Test provides numerous advantages:
- Early Diagnosis: Detect sickle cell disease before symptoms become severe
- Accurate Carrier Detection: Identify individuals with sickle cell trait
- Family Planning Guidance: Make informed reproductive decisions
- Personalized Treatment: Enable targeted management strategies
- Comprehensive Analysis: NGS technology detects multiple mutations simultaneously
- High Accuracy: 99.9% detection rate for known HBB gene mutations
Understanding Your Test Results
Your genetic test results will be carefully interpreted by our expert genetic counselors and hematologists:
- Normal Result: No sickle cell mutations detected in the HBB gene
- Sickle Cell Trait: One copy of the mutated gene (carrier status)
- Sickle Cell Disease: Two copies of the mutated gene
- Compound Heterozygote: Different mutations on each HBB gene copy
- Variant of Unknown Significance: Rare mutation requiring further evaluation
All positive results include detailed genetic counseling to help you understand implications and next steps.
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | HBB Gene Sickle Cell Anemia NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next Generation Sequencing (NGS) |
Pre-Test Requirements
Before scheduling your test, please prepare:
- Complete clinical history documentation
- Genetic counseling session to create family pedigree chart
- Discussion of testing implications with healthcare provider
- Understanding of potential results and their significance
Nationwide Availability
We have testing facilities conveniently located across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network ensures accessible genetic testing services for patients nationwide.
Take Control of Your Genetic Health
Don’t wait to get the answers you need about your genetic health. Early detection of sickle cell disease can significantly improve quality of life and treatment outcomes. Our team of genetic specialists and hematologists are ready to provide comprehensive care and support throughout your testing journey.
Ready to schedule your HBB Gene Sickle Cell Anemia NGS Genetic DNA Test? Call our genetic counseling team today at +1(267) 388-9828 or book your appointment online. Take the first step toward understanding your genetic health and making informed decisions for your future.
