GNA13 Gene Vascular System Defects Due to GNA13 Deficiency NGS Genetic DNA Test
Understanding GNA13 Gene Vascular System Defects
The GNA13 Gene Vascular System Defects NGS Genetic DNA Test represents a breakthrough in molecular diagnostics for vascular disorders. This sophisticated test specifically targets mutations in the GNA13 gene, which plays a critical role in regulating vascular development and function. GNA13 encodes a subunit of heterotrimeric G proteins that are essential for intracellular signaling pathways controlling blood vessel formation, maintenance, and repair.
When GNA13 gene function is compromised due to genetic mutations, it can lead to significant vascular system defects including abnormal blood vessel development, impaired vascular integrity, and increased susceptibility to vascular malformations. Early detection through this advanced genetic test enables proactive management and personalized treatment approaches for affected individuals.
What This Test Detects and Measures
Our comprehensive NGS-based genetic test provides detailed analysis of the GNA13 gene to identify:
- Pathogenic mutations causing GNA13 deficiency
- Single nucleotide variants (SNVs) affecting gene function
- Insertions and deletions (indels) disrupting protein structure
- Copy number variations impacting gene dosage
- Regulatory region mutations affecting gene expression
The test utilizes state-of-the-art Next-Generation Sequencing technology that provides complete coverage of the GNA13 gene coding regions, splice sites, and regulatory elements. This comprehensive approach ensures high detection sensitivity for various mutation types that could contribute to vascular system abnormalities.
Who Should Consider This Genetic Test
Clinical Indications and Symptoms
This test is particularly recommended for individuals presenting with:
- Unexplained vascular malformations or abnormalities
- Recurrent bleeding episodes without clear cause
- Family history of vascular disorders or genetic conditions
- Developmental vascular abnormalities detected in infancy or childhood
- Multiple vascular anomalies affecting different body systems
- Poor wound healing or abnormal scar formation
- Unexplained bruising or hematoma formation
At-Risk Populations
- Individuals with known family history of GNA13-related disorders
- Patients with syndromic features suggesting genetic vascular conditions
- Those with congenital vascular abnormalities requiring genetic diagnosis
- Families seeking preconception or prenatal genetic counseling
Significant Benefits of GNA13 Genetic Testing
Undergoing the GNA13 Gene Vascular System Defects DNA Test offers numerous advantages:
- Accurate Diagnosis: Provides definitive molecular diagnosis for vascular conditions
- Personalized Treatment: Enables targeted therapeutic approaches based on genetic findings
- Family Planning: Supports informed reproductive decisions and genetic counseling
- Early Intervention: Facilitates proactive management before severe complications develop
- Comprehensive Risk Assessment: Identifies associated health risks for comprehensive care planning
- Research Contribution: Advances understanding of vascular genetics and treatment options
Understanding Your Test Results
Interpretation Guidelines
Your genetic test results will be carefully analyzed and interpreted by our expert geneticists:
- Positive Result: Indicates presence of pathogenic GNA13 mutation(s) confirming diagnosis
- Negative Result: Suggests absence of detectable mutations in the GNA13 gene
- Variant of Uncertain Significance (VUS): Requires additional family studies and clinical correlation
- Carrier Status: Identifies individuals with single mutation copy who may pass condition to offspring
Post-Test Guidance
Following your test results, our genetic counseling team provides:
- Comprehensive explanation of genetic findings and clinical implications
- Personalized management recommendations based on mutation type
- Family testing guidance and cascade screening options
- Referrals to appropriate vascular specialists and multidisciplinary care
- Long-term monitoring and surveillance recommendations
Test Details and Pricing
| Test Parameter | Details |
|---|---|
| Test Name | GNA13 Gene Vascular System Defects Due to GNA13 Deficiency NGS Genetic DNA Test |
| Regular Price | $700 USD |
| Discount Price | $500 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
| Specialty | Genetics |
| Department | Genetics |
| Disease Type | Vascular Diseases |
Pre-Test Requirements and Preparation
To ensure optimal testing conditions, please note the following requirements:
- Complete clinical history documentation for the patient
- Genetic counseling session to create detailed family pedigree chart
- Identification of family members affected by vascular system defects
- Informed consent for genetic testing and potential implications
- Insurance pre-authorization if applicable
Nationwide Testing Availability
We proudly offer comprehensive genetic testing services across the United States with convenient locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Jacksonville, Fort Worth, Columbus, San Francisco, and many other cities. Our extensive network ensures accessible, high-quality genetic testing for patients nationwide.
Take Action for Your Vascular Health
Don’t let uncertainty about vascular health concerns affect your quality of life. Our GNA13 Gene Vascular System Defects DNA Test provides the clarity and answers you need for informed healthcare decisions. With our discounted price of $500 USD (regularly $700 USD), advanced NGS technology, and comprehensive genetic analysis, you can take control of your vascular health with confidence.
Ready to schedule your test? Contact our genetic specialists today at +1(267) 388-9828 or book your appointment online. Our team is available to answer your questions, discuss testing options, and guide you through the genetic testing process with compassion and expertise.
