Glomerular Basement Membrane GBM Antibody IgG Test
Understanding the GBM Antibody IgG Test
The Glomerular Basement Membrane (GBM) Antibody IgG Test is a sophisticated diagnostic examination that plays a vital role in identifying autoimmune disorders affecting kidney function. This specialized blood test detects the presence of IgG antibodies that specifically target the glomerular basement membrane – the critical filtering structure within the kidneys’ nephrons. When these antibodies attack the GBM, they trigger an inflammatory response that can rapidly damage kidney tissue and compromise renal function.
What Does This Test Measure?
This advanced immunopathology test specifically measures:
- IgG class antibodies directed against the alpha-3 chain of type IV collagen in the glomerular basement membrane
- Autoimmune activity targeting kidney filtration structures
- Evidence of anti-GBM disease, the hallmark of Goodpasture syndrome
- The severity of autoimmune kidney involvement through antibody levels
Who Should Consider This Test?
This test is particularly important for individuals experiencing:
- Unexplained hematuria (blood in urine) or proteinuria
- Rapidly progressive glomerulonephritis
- Unexplained kidney failure or declining renal function
- Respiratory symptoms combined with kidney issues
- Suspected autoimmune kidney disorders
- Family history of autoimmune kidney diseases
- Patients being evaluated by nephrologists for unexplained renal impairment
Clinical Benefits of GBM Antibody Testing
Early detection through GBM antibody testing provides numerous clinical advantages:
- Early Diagnosis: Identifies autoimmune kidney disease before irreversible damage occurs
- Treatment Guidance: Helps nephrologists develop targeted treatment plans
- Disease Monitoring: Tracks treatment effectiveness and disease progression
- Prevention of Complications: Early intervention can prevent end-stage renal disease
- Comprehensive Assessment: Provides crucial information for managing complex autoimmune conditions
Understanding Your Test Results
Your GBM Antibody IgG test results will fall into one of several categories:
Negative Result
A negative result indicates no detectable IgG antibodies against the glomerular basement membrane. This typically rules out anti-GBM disease as the cause of kidney symptoms, though your physician may recommend additional testing based on clinical presentation.
Positive Result
A positive result confirms the presence of anti-GBM antibodies and supports a diagnosis of Goodpasture syndrome or anti-GBM disease. The antibody level often correlates with disease activity and treatment response.
Borderline Result
Borderline results may require repeat testing or additional clinical correlation. Your nephrologist will interpret these results in the context of your symptoms and other laboratory findings.
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | Glomerular Basement Membrane GBM Antibody IgG Test |
| Regular Price | $126 USD |
| Discount Price | $88 USD |
| Turnaround Time | 1 Week |
| Sample Type | 2 mL (1 mL min.) serum from 1 SST |
| Sample Handling | Ship refrigerated or frozen |
| Preparation | No special preparation required |
| Testing Method | Enzyme Immunoassay |
Nationwide Testing Availability
We provide comprehensive GBM Antibody IgG testing services across the United States, with convenient locations in all major metropolitan areas including:
- New York City and surrounding areas
- Los Angeles and Southern California
- Chicago and the Midwest region
- Houston and Texas locations
- Phoenix and Arizona facilities
- Philadelphia and Pennsylvania centers
- San Antonio and additional Texas sites
- San Diego and California locations
- Dallas and North Texas facilities
- San Jose and Bay Area centers
Take Action for Your Kidney Health
Don’t wait for kidney symptoms to progress. Early detection of autoimmune kidney disorders through GBM antibody testing can make a significant difference in treatment outcomes and long-term kidney function. Our specialized immunopathology testing provides the accurate, reliable results that nephrologists need to make informed treatment decisions.
Ready to schedule your GBM Antibody IgG Test? Contact our dedicated healthcare team today to book your appointment or learn more about this essential diagnostic test.
Call or WhatsApp: +1(267) 388-9828
Take the first step toward understanding your kidney health with our advanced GBM Antibody IgG testing. With our discounted price of only $88 and convenient locations nationwide, comprehensive kidney diagnostics have never been more accessible.

