GJB3 Gene Deafness Autosomal Recessive NGS Genetic DNA Test
Understanding Hereditary Hearing Loss
Hearing loss affects millions of Americans, with genetic factors playing a significant role in many cases. The GJB3 Gene Deafness Autosomal Recessive NGS Genetic DNA Test represents a breakthrough in genetic diagnostics, specifically targeting mutations in the GJB3 gene that cause autosomal recessive nonsyndromic hearing loss. This advanced testing method provides families and healthcare providers with critical information for managing hereditary hearing conditions.
What Does This Test Measure?
Our comprehensive genetic screening focuses on detecting specific mutations in the GJB3 (Gap Junction Beta 3) gene, which encodes connexin 31 protein. This protein is essential for proper functioning of gap junctions in the inner ear, facilitating communication between cells and maintaining auditory function. The test identifies:
- Pathogenic variants in the GJB3 gene
- Autosomal recessive inheritance patterns
- Specific mutations associated with DFNB2 and DFNA2 hearing loss types
- Carrier status for family planning purposes
Who Should Consider This Test?
This genetic screening is recommended for individuals experiencing:
- Unexplained hearing loss in childhood or early adulthood
- Family history of hereditary hearing impairment
- Progressive hearing loss without clear environmental causes
- Planning pregnancy with known family history of genetic hearing disorders
- Suspected autosomal recessive inheritance patterns in hearing loss
Clinical Indications Include:
- Progressive sensorineural hearing loss
- Early-onset hearing impairment
- Family members with similar hearing patterns
- Consanguineous relationships with hearing loss history
Benefits of GJB3 Genetic Testing
Early detection through genetic testing provides numerous advantages:
- Early Intervention: Identify hearing loss risks before significant impairment occurs
- Family Planning: Make informed decisions about genetic risks to future children
- Personalized Management: Develop targeted hearing conservation strategies
- Peace of Mind: Understand your genetic predisposition to hearing conditions
- Comprehensive Analysis: Next Generation Sequencing provides thorough genetic assessment
Understanding Your Test Results
Your genetic test results will fall into one of several categories:
- Positive Result: Indicates presence of pathogenic GJB3 mutations associated with hearing loss risk
- Negative Result: No detected mutations in the analyzed GJB3 gene regions
- Variant of Uncertain Significance: Genetic changes with unclear clinical implications requiring further evaluation
- Carrier Status: Identification of single mutation copy indicating carrier status without disease manifestation
All results include comprehensive genetic counseling to help you understand the implications and next steps. Our team of genetic specialists will guide you through result interpretation and management recommendations.
Test Pricing and Details
| Test Component | Details |
|---|---|
| Test Name | GJB3 Gene Deafness Autosomal Recessive NGS Genetic DNA Test |
| Regular Price | $700 USD |
| Discount Price | $500 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next Generation Sequencing (NGS) Technology |
Nationwide Accessibility
We proudly serve patients across the United States with convenient testing locations in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified collection centers ensures easy access to this vital genetic testing service.
Take Control of Your Genetic Health
Don’t let uncertainty about hereditary hearing loss affect your quality of life. The GJB3 Gene Deafness Autosomal Recessive NGS Genetic DNA Test provides the clarity you need to make informed health decisions. Our team of ENT specialists and genetic counselors are ready to support you through every step of the testing process.
Ready to schedule your test? Call or WhatsApp us today at +1(267) 388-9828 to book your appointment or get more information about this life-changing genetic screening.
Take the first step toward understanding your genetic hearing health. Our compassionate team is here to provide the expert care and guidance you deserve.
