Gastrin Stimulation by Secretin Test
Understanding the Gastrin Stimulation by Secretin Test
The Gastrin Stimulation by Secretin Test represents a sophisticated diagnostic approach for evaluating gastrointestinal hormone function and detecting rare neuroendocrine tumors. This specialized procedure measures gastrin levels in response to secretin administration, providing crucial insights into pancreatic and duodenal function. Gastrin, a hormone produced by G-cells in the stomach and duodenum, plays a vital role in regulating gastric acid secretion and maintaining digestive health.
What Does This Test Measure?
The Gastrin Stimulation by Secretin Test specifically evaluates:
- Baseline gastrin levels before secretin administration
- Gastrin response patterns following secretin stimulation
- Abnormal gastrin secretion indicative of gastrinomas
- Hormonal dynamics in Zollinger-Ellison syndrome
- Pancreatic and duodenal endocrine function
Who Should Consider This Test?
This diagnostic test is particularly important for individuals experiencing:
- Persistent peptic ulcers resistant to conventional treatment
- Recurrent gastrointestinal bleeding or perforation
- Chronic diarrhea with malabsorption symptoms
- Unexplained abdominal pain and discomfort
- Symptoms suggestive of multiple endocrine neoplasia type 1 (MEN1)
- Family history of neuroendocrine tumors
- Elevated gastrin levels in previous blood tests
Clinical Indications and Symptoms
Patients presenting with the following clinical scenarios may benefit from this specialized testing:
- Severe gastroesophageal reflux disease (GERD) unresponsive to standard therapy
- Multiple peptic ulcers in unusual locations
- Complications from excessive gastric acid production
- Suspected pancreatic or duodenal neuroendocrine tumors
- Monitoring known gastrinoma patients during treatment
Benefits of Gastrin Stimulation Testing
Choosing the Gastrin Stimulation by Secretin Test offers numerous advantages:
- Early Detection: Identifies gastrin-producing tumors before they become symptomatic
- Accurate Diagnosis: Provides definitive confirmation of Zollinger-Ellison syndrome
- Treatment Guidance: Helps determine appropriate therapeutic approaches
- Monitoring Capability: Enables tracking of treatment effectiveness
- Comprehensive Assessment: Evaluates multiple aspects of gastrointestinal hormone function
- Rapid Results: Same-day reporting for timely clinical decisions
Test Procedure Details
The Gastrin Stimulation by Secretin Test follows a precise protocol:
- Preparation: Overnight fasting is mandatory before the test
- Baseline Sample: Initial blood draw to establish baseline gastrin levels
- Secretin Administration: Intravenous injection of secretin (2 U/kg body weight)
- Timed Specimens: Additional blood draws at 5, 10, 15, 20, 25, and 30 minutes post-injection
- Sample Handling: All specimens are shipped frozen and must not be thawed
- Documentation: Each container must be clearly marked with collection time
Understanding Your Test Results
Interpreting Gastrin Stimulation by Secretin Test results requires specialized medical expertise:
- Normal Response: Minimal or no increase in gastrin levels after secretin administration
- Positive for Gastrinoma: Significant rise in gastrin levels (typically >120 pg/mL increase)
- Borderline Results: May require additional testing or clinical correlation
- Pattern Analysis: The timing and magnitude of gastrin response provide diagnostic clues
- Clinical Context: Results must be interpreted alongside symptoms and imaging studies
Test Methodology and Technology
Our laboratory employs advanced Chemiluminescent Immunoassay technology for precise gastrin measurement. This state-of-the-art methodology ensures:
- High sensitivity and specificity for gastrin detection
- Accurate quantification across the entire measurement range
- Reliable and reproducible results
- Minimal interference from other substances
- Compliance with international quality standards
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $288 |
| Regular Price | $450 |
Nationwide Testing Availability
We proudly offer the Gastrin Stimulation by Secretin Test across our extensive network of testing centers throughout the United States. Our facilities are conveniently located in:
- New York City and surrounding metropolitan areas
- Los Angeles and Southern California regions
- Chicago and Illinois locations
- Houston, Dallas, and Texas centers
- Phoenix, Arizona testing facilities
- All other major metropolitan areas nationwide
Schedule Your Test Today
Take control of your gastrointestinal health with our comprehensive Gastrin Stimulation by Secretin Test. Our experienced medical team and state-of-the-art laboratory facilities ensure accurate results and personalized care. Contact us now to schedule your appointment:
Call or WhatsApp: +1(267) 388-9828
Our dedicated healthcare professionals are available to answer your questions, explain the testing process, and help you understand how this specialized diagnostic test can benefit your health journey. Don’t wait to address your gastrointestinal concerns – book your Gastrin Stimulation by Secretin Test today and take the first step toward accurate diagnosis and effective treatment.
