FISH t(8;21) or LSI ETO/AML1 Test
Comprehensive Genetic Testing for Leukemia Diagnosis
The FISH t(8;21) or LSI ETO/AML1 Test represents a cutting-edge molecular diagnostic approach for detecting specific chromosomal abnormalities associated with acute myeloid leukemia (AML). This sophisticated cytogenetic analysis plays a vital role in modern hematological diagnostics, providing clinicians with critical information for accurate disease classification and personalized treatment planning.
What This Test Measures and Detects
The FISH t(8;21) or LSI ETO/AML1 Test specifically identifies the translocation between chromosomes 8 and 21, which results in the formation of the ETO/AML1 fusion gene. This genetic abnormality is particularly significant because:
- Detects the t(8;21)(q22;q22) chromosomal translocation
- Identifies the ETO/AML1 fusion gene formation
- Provides highly sensitive detection of minimal residual disease
- Offers superior resolution compared to conventional karyotyping
- Enables precise monitoring of treatment response
Who Should Consider This Test
This specialized genetic test is recommended for individuals presenting with symptoms or clinical findings suggestive of acute myeloid leukemia, including:
- Patients with unexplained fatigue, weakness, or pallor
- Individuals experiencing frequent infections or fever
- Those with unusual bleeding or bruising tendencies
- Patients showing abnormal blood cell counts
- Individuals with bone pain or joint discomfort
- Patients with enlarged lymph nodes or spleen
- Those with a family history of hematological malignancies
Clinical Benefits of the FISH t(8;21) Test
Choosing the FISH t(8;21) or LSI ETO/AML1 Test provides numerous clinical advantages for both patients and healthcare providers:
- Accurate Diagnosis: Provides definitive identification of AML subtypes
- Prognostic Information: Helps predict disease course and treatment response
- Treatment Guidance: Informs targeted therapy selection
- Disease Monitoring: Enables sensitive detection of residual disease
- Early Detection: Identifies genetic abnormalities before clinical symptoms manifest
- Personalized Medicine: Supports development of individualized treatment plans
Understanding Your Test Results
Interpreting FISH t(8;21) test results requires specialized expertise from our certified cytogeneticists and hematologists:
- Positive Result: Indicates presence of the t(8;21) translocation, confirming AML diagnosis with specific genetic features
- Negative Result: Suggests absence of this specific translocation, though other genetic abnormalities may be present
- Quantitative Analysis: Provides percentage of cells carrying the abnormality, useful for monitoring treatment response
- Clinical Correlation: Results are interpreted in context of complete blood count, bone marrow findings, and clinical presentation
Test Pricing Information
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $150 |
| Regular Price | $188 |
Sample Requirements and Processing
Our laboratory maintains strict quality standards for sample collection and processing:
- Sample Type: 5 mL (3 mL minimum) whole blood OR 4 mL (2 mL minimum) bone marrow
- Collection Tubes: Two Green Top (Sodium Heparin) tubes required
- Shipping Conditions: Maintain temperature at 18-22°C during transport
- Important Note: DO NOT FREEZE samples under any circumstances
- Required Documentation: Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory
Turnaround Time and Reporting
We understand the urgency of genetic testing in leukemia diagnosis and provide efficient service:
- Sample Acceptance: Daily by 4:00 PM
- Report Delivery: 4 working days from sample receipt
- Expert Interpretation: All reports include detailed analysis by board-certified specialists
- Digital Access: Secure online portal for convenient result retrieval
Nationwide Accessibility
General Genetics Corporation maintains comprehensive testing facilities across the United States, with convenient locations in:
- New York City and surrounding metropolitan areas
- Los Angeles and Southern California regions
- Chicago and Midwest territories
- Houston and Texas medical centers
- Phoenix and Southwest facilities
- All other major US cities and medical hubs
Take Action for Your Health
Early and accurate genetic testing can significantly impact leukemia treatment outcomes. Our FISH t(8;21) or LSI ETO/AML1 Test provides the critical genetic information needed for optimal patient care. Don’t delay in obtaining this essential diagnostic information.
Book your FISH t(8;21) or LSI ETO/AML1 Test today by calling our dedicated healthcare line at +1(267) 388-9828 or schedule your appointment through our online booking system.
Our team of genetic specialists, oncologists, and hematologists is committed to providing you with accurate, timely, and comprehensive genetic testing services to support your healthcare journey.
